Incomplete hemolytic-uremic syndrome in Argentinean children with bloody diarrhea.
J Pediatr
; 127(3): 364-7, 1995 Sep.
Article
en En
| MEDLINE
| ID: mdl-7658263
ABSTRACT
Argentina has an exceptionally high frequency of hemolytic-uremic syndrome (HUS). We sought to define prospectively the role of verocytotoxins (Shiga-like toxins [SLTs]) in 254 Argentinean children with grossly bloody diarrhea during spring and summer. Free fecal SLTs (I/II) and/or DNA probe-positive isolates were found in 99 (39%) of the children. During the follow-up period, HUS developed in 6 patients (4 with evidence of recent SLT infection based on stool studies); another 14 patients had some, but not all, of the abnormalities seen in typical HUS. The development of HUS or incomplete HUS in these children was significantly associated with recent SLT-Escherichia coli infection (p = 0.024). The high incidence of SLT-associated bloody diarrhea in Argentina explains, at least partially, the unusually high frequency of HUS. Our data indicate that incomplete forms of HUS may be common in patients with SLT-associated bloody diarrhea.
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Base de datos:
MEDLINE
Asunto principal:
Diarrea
/
Diarrea Infantil
/
Síndrome Hemolítico-Urémico
Tipo de estudio:
Diagnostic_studies
/
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
País/Región como asunto:
America do sul
/
Argentina
Idioma:
En
Revista:
J Pediatr
Año:
1995
Tipo del documento:
Article
País de afiliación:
Argentina