A study of Toxoplasma and Cytomegalovirus serology in tuberculosis and in HIV-infected patients in Burkina Faso.
Acta Trop
; 59(2): 149-54, 1995 May.
Article
en En
| MEDLINE
| ID: mdl-7676906
ABSTRACT
Seroreactivity to Toxoplasma gondii (Tg) and to Cytomegalovirus (Cmv) was compared between symptomatic HIV-infected patients (40 with pulmonary tuberculosis and 38 with AIDS) and HIV-seronegative patients (40 tuberculosis patients and 30 healthy patients), in an urban area of Burkina Faso. Prevalence of IgG antibodies to Tg antigens (> 50.0%) did not differ amongst the four groups, but tuberculosis HIV+ patients and AIDS patients showed more higher titers of Tg antibodies more often than healthy patients (p < 0.05 and p < 0.005, respectively). Prevalence of specific IgG to Cmv was higher in tuberculosis HIV-seronegative patients (97.5%) and in AIDS patients (100%) than in healthy patients (82%; p < 0.03 and p < 0.001, respectively). Higher Cmv antibodies titers were found in relation to AIDS but also to tuberculosis. Tuberculosis HIV+ as tuberculosis HIV-patients showed higher Cmv antibodies titers than healthy patients (p < 0.002 and < 0.02 respectively). These data emphasize the need for taking into account the risk of Tg reactivation during the follow-up of HIV infected patients in Burkina Faso and suggest possible relationships between Cmv and tuberculosis reactivations.
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Base de datos:
MEDLINE
Asunto principal:
Toxoplasma
/
Tuberculosis Pulmonar
/
Anticuerpos Antiprotozoarios
/
Infecciones Oportunistas Relacionadas con el SIDA
/
Citomegalovirus
/
Anticuerpos Antivirales
Tipo de estudio:
Risk_factors_studies
Límite:
Adult
/
Animals
/
Female
/
Humans
/
Male
/
Middle aged
País/Región como asunto:
Africa
Idioma:
En
Revista:
Acta Trop
Año:
1995
Tipo del documento:
Article
País de afiliación:
Burquina Faso