[Immunologic study on patients with head and neck cancer treated with thymopentin associated with surgery, chemotherapy and radiotherapy]. / Studio immunologico di pazienti con neoplasie ORL trattati con timopentina con terapia adiuvante la chirurgia, la chemioterapia e la radioterapia.
Acta Otorhinolaryngol Ital
; 14(6): 611-25, 1994.
Article
en It
| MEDLINE
| ID: mdl-7740961
ABSTRACT
Patients with H&N tumours treated with surgery, chemo- and radiotherapy also underwent an immunologic therapy with timopentina to evaluate clinic and immunologic efficacy during a 1-year follow-up. Twenty-five patients were recorded in this study divided at random into two groups. In group A the patients were administered timopentina (50 mg/3 times per week/6 weeks) subcutaneously in 4 o 5 cycles during the year. Group B were not administered timopentina. The immunologic state was assessed through investigation of the following Evaluation of PBL and their T and B cell subpopulations Phagocytosis and blastigenesis Surface receptor and soluble receptor of IL2 NK activity IL1 production. The immunologic values of the two groups were correlated against a control group of twenty non-neoplastic patients. Our study revealed a better immunologic conditions at the end of follow-up in patients treated with timopentina compared to the other patients.
Buscar en Google
Base de datos:
MEDLINE
Asunto principal:
Orofaringe
/
Neoplasias Orofaríngeas
/
Neoplasias Laríngeas
/
Nasofaringe
/
Neoplasias Nasofaríngeas
/
Timopentina
/
Inmunoterapia
/
Laringe
Tipo de estudio:
Clinical_trials
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Humans
Idioma:
It
Revista:
Acta Otorhinolaryngol Ital
Año:
1994
Tipo del documento:
Article