[An unusual case of subacute sclerosing panencephalitis].
Harefuah
; 128(5): 273-6, 336, 335, 1995 Mar 01.
Article
en He
| MEDLINE
| ID: mdl-7744346
ABSTRACT
A 25-year-old man was admitted following deterioration in behavior and onset of blindness. He soon became comatose and died 6 weeks later. Brain biopsy showed nuclear inclusion bodies resembling viral capsids, astrocytosis and perivascular lymphocytic cuffing but no demyelination. The diagnosis of subacute sclerosing panencephalitis was made on finding:
measles virus antigens in both serum and cerebrospinal fluid, the identification of measles RNA sequences in brain tissue by the polymerase chain reaction, and intense, oligoclonal, IgG-banding in the CSF. However, the relatively advanced age of the patient, the absence of myoclonus and the nondistinctive EEG profile lacking synchronous bursts of high-voltage slow and sharp waves, are unusual.
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Base de datos:
MEDLINE
Asunto principal:
Panencefalitis Esclerosante Subaguda
Tipo de estudio:
Diagnostic_studies
/
Prognostic_studies
Límite:
Adult
/
Humans
/
Male
Idioma:
He
Revista:
Harefuah
Año:
1995
Tipo del documento:
Article