Quantitative in vivo iontophoretic studies.
J Pharm Sci
; 83(1): 12-7, 1994 Jan.
Article
en En
| MEDLINE
| ID: mdl-8138902
ABSTRACT
An experimental methodology was developed to evaluate the physicochemical basis for in vitro-in vivo correlations in iontophoretic delivery situations. This experimental methodology can be used to quantitatively evaluate the extent of interaction between chemical permeation enhancers and iontophoresis for drug delivery. The inherent advantages of using Ag/AgCl electrodes are fully exploited to control pH and minimize depletion of permeant during prolonged periods of iontophoresis.
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Base de datos:
MEDLINE
Asunto principal:
Piel
/
Iontoforesis
Límite:
Animals
Idioma:
En
Revista:
J Pharm Sci
Año:
1994
Tipo del documento:
Article