Neuropeptide processing in pathophysiology.
Agents Actions Suppl
; 42: 211-26, 1993.
Article
en En
| MEDLINE
| ID: mdl-8356926
ABSTRACT
Neuropeptides (peptides synthesized and secreted by neurons) perform many functions in the central nervous system as neurotransmitters, neuromodulators and neurotrophic factors. Neuropeptides are important regulators of amine neurotransmitter release, and can be identified as playing important roles in several pathological states. Neuropeptides are synthesized as protein precursors that are processed enzymatically to yield the biologically active peptides. Many neuropeptides having defined roles are further processed enzymatically to yield fragments having totally different actions. Examples discussed are substance P, adrenocorticotrophic hormone, endorphins and vasopressin.
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Base de datos:
MEDLINE
Asunto principal:
Neuropéptidos
/
Enfermedades del Sistema Nervioso
Tipo de estudio:
Prognostic_studies
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Agents Actions Suppl
Año:
1993
Tipo del documento:
Article