Redistribution of myocardial perfusion during permanent dual chamber pacing in symptomatic non-obstructive hypertrophic cardiomyopathy: a quantitative positron emission tomography study.

ABSTRACT

Dual chamber pacing causes significant symptomatic improvement in many patients with hypertrophic cardiomyopathy. The mechanism behind this beneficial response is not fully understood. Positron emission tomography showed a redistribution of myocardial flow during pacing in a patient with non-obstructive hypertrophic cardiomyopathy. Early septal activation reduced septal fibre strain and blood flow and increased septal perfusion reserve.