HLA-A, -B, -DR and -DQ antigens in black patients with infective endocarditis.
S Afr Med J
; 88 Suppl 1: C10-2, 1998 Feb.
Article
en En
| MEDLINE
| ID: mdl-9542489
ABSTRACT
In order to determine if genetically determined immune response factors could play a role in the pathogenesis of infective endocarditis in black patients, we performed HLA-A and HLA-B typing in 38 patients with this disease and HLA-DR and HLA-DQ typing in 33 and 27 of these individuals, respectively. HLA typing was also carried out in a control group of normal black adults. The HLA typing was done by means of a standard microlymphocytotoxicity test. No difference in HLA-A, HLA-B, HLA-DR and HLA-DQ antigen frequencies between patients and controls were noted. This study did not provide any evidence that genetic factors could contribute to a disposition to infective endocarditis.
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Base de datos:
MEDLINE
Asunto principal:
Población Negra
/
Endocarditis Bacteriana
/
Antígenos HLA
Tipo de estudio:
Observational_studies
Límite:
Adolescent
/
Adult
/
Child
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
S Afr Med J
Año:
1998
Tipo del documento:
Article