Iodine-131-metaiodobenzylguanidine uptake in metastatic carcinoid tumor to the orbit.
J Nucl Med
; 39(4): 647-50, 1998 Apr.
Article
en En
| MEDLINE
| ID: mdl-9544672
ABSTRACT
Metastatic tumor is one of several etiologies of space-occupying masses in the orbit that accounts for 1%-13% of all orbital masses (1). In the adult patient population, breast cancer is the most common tumor to metastasize to the orbit followed by metastases from the lung, prostate and gastrointestinal tract (2). It is rare for carcinoid tumors to metastasize to the eye or to the orbit. Carcinoid tumors arise from Kulchitsky cells that originate in the neural crest. Histologically, these tumors resemble, but are not as aggressive as, adenocarcinomas. Most carcinoids arise in the gastrointestinal tract or the lung. The most common site for carcinoid metastases is the liver. On anatomical imaging studies, such as CT and magnetic resonance imaging, metastatic orbital carcinoid tumors appear as nonspecific tumor masses. Carcinoid tumors have an affinity for uptake of the radiopharmaceutical 131I-metaiodobenzylguanidine (MIBG) (3). We report a case of a patient with a known carcinoid tumor who developed a left orbital mass that demonstrated abnormal uptake of 131I-MIBG indicative of metastatic carcinoid tumor to the orbit.
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Base de datos:
MEDLINE
Asunto principal:
Neoplasias Orbitales
/
Tumor Carcinoide
/
Radiofármacos
/
3-Yodobencilguanidina
/
Radioisótopos de Yodo
Tipo de estudio:
Diagnostic_studies
Límite:
Aged
/
Humans
/
Male
Idioma:
En
Revista:
J Nucl Med
Año:
1998
Tipo del documento:
Article
País de afiliación:
Estados Unidos