Detalhe da pesquisa
1.
Immunotherapy targeting the C-terminal domain of TDP-43 decreases neuropathology and confers neuroprotection in mouse models of ALS/FTD.
Neurobiol Dis
; 179: 106050, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36809847
2.
An effector-reduced anti-ß-amyloid (Aß) antibody with unique aß binding properties promotes neuroprotection and glial engulfment of Aß.
J Neurosci
; 32(28): 9677-89, 2012 Jul 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-22787053
3.
Discovery and structure activity relationship of small molecule inhibitors of toxic ß-amyloid-42 fibril formation.
J Biol Chem
; 287(41): 34786-800, 2012 Oct 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-22891248
4.
Targeting amyotrophic lateral sclerosis by neutralizing seeding-competent TDP-43 in CSF.
Brain Commun
; 5(6): fcad306, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-38025276
5.
Abeta42 neurotoxicity is mediated by ongoing nucleated polymerization process rather than by discrete Abeta42 species.
J Biol Chem
; 286(10): 8585-8596, 2011 Mar 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-21156804
6.
Antibody semorinemab reduces tau pathology in a transgenic mouse model and engages tau in patients with Alzheimer's disease.
Sci Transl Med
; 13(593)2021 05 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33980574
7.
TREM-1 expression is increased in the synovium of rheumatoid arthritis patients and induces the expression of pro-inflammatory cytokines.
Rheumatology (Oxford)
; 48(11): 1352-8, 2009 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-19713442
8.
Calpain-mediated tau fragmentation is altered in Alzheimer's disease progression.
Sci Rep
; 8(1): 16725, 2018 11 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-30425303
9.
Novel Phospho-Tau Monoclonal Antibody Generated Using a Liposomal Vaccine, with Enhanced Recognition of a Conformational Tauopathy Epitope.
J Alzheimers Dis
; 56(2): 585-599, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28035925
10.
Anti-inflammatory effects of bifidobacteria by inhibition of LPS-induced NF-kappaB activation.
World J Gastroenterol
; 12(23): 3729-35, 2006 Jun 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-16773690
11.
Structure of Crenezumab Complex with Aß Shows Loss of ß-Hairpin.
Sci Rep
; 6: 39374, 2016 12 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27996029
12.
Antibody-Mediated Targeting of Tau In Vivo Does Not Require Effector Function and Microglial Engagement.
Cell Rep
; 16(6): 1690-1700, 2016 08 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27475227
13.
Yogurt and gut function.
Am J Clin Nutr
; 80(2): 245-56, 2004 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-15277142
14.
Vitamin E and gene expression in immune cells.
Ann N Y Acad Sci
; 1031: 96-101, 2004 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-15753137
15.
Increased efflux of amyloid-ß peptides through the blood-brain barrier by muscarinic acetylcholine receptor inhibition reduces pathological phenotypes in mouse models of brain amyloidosis.
J Alzheimers Dis
; 38(4): 767-86, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24072071
16.
Efficacy and safety of a liposome-based vaccine against protein Tau, assessed in tau.P301L mice that model tauopathy.
PLoS One
; 8(8): e72301, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23977276
17.
Bifidobacterium lactis attenuates onset of inflammation in a murine model of colitis.
World J Gastroenterol
; 17(4): 459-69, 2011 Jan 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-21274375
18.
Nutrition and the aging immune response.
Nestle Nutr Workshop Ser Clin Perform Programme
; 6: 207-20; discussion 220-1, 2002.
Artigo
em Inglês
| MEDLINE | ID: mdl-16969976
19.
N(epsilon)-carboxymethyllysine-modified proteins are unable to bind to RAGE and activate an inflammatory response.
Mol Nutr Food Res
; 52(3): 370-8, 2008 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-18320574
20.
Age and vitamin E-induced changes in gene expression profiles of T cells.
J Immunol
; 177(9): 6052-61, 2006 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17056531