Detalhe da pesquisa
1.
Gene expression profiles of multiple brain regions in rats differ between developmental and postpubertal exposure to valproic acid.
J Appl Toxicol
; 42(5): 864-882, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34779009
2.
Downregulation of low-density lipoprotein receptor class A domain-containing protein 4 (Ldlrad4) in the liver of rats treated with nongenotoxic hepatocarcinogen to induce transforming growth factor ß signaling promoting cell proliferation and suppressing apoptosis in early hepatocarcinogenesis.
J Appl Toxicol
; 40(11): 1467-1479, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32596862
3.
Genetic toxicology in silico protocol.
Regul Toxicol Pharmacol
; 107: 104403, 2019 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-31195068
4.
Differential responses on energy metabolic pathway reprogramming between genotoxic and non-genotoxic hepatocarcinogens in rat liver cells.
J Toxicol Pathol
; 32(4): 261-274, 2019 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-31719753
5.
In silico toxicology protocols.
Regul Toxicol Pharmacol
; 96: 1-17, 2018 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-29678766
6.
Developmental cuprizone exposure impairs oligodendrocyte lineages differentially in cortical and white matter tissues and suppresses glutamatergic neurogenesis signals and synaptic plasticity in the hippocampal dentate gyrus of rats.
Toxicol Appl Pharmacol
; 290: 10-20, 2016 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26577399
7.
Global gene expression profiles in brain regions reflecting abnormal neuronal and glial functions targeting myelin sheaths after 28-day exposure to cuprizone in rats.
Toxicol Appl Pharmacol
; 310: 20-31, 2016 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27523638
8.
Gene expression profiling of the hippocampal dentate gyrus in an adult toxicity study captures a variety of neurodevelopmental dysfunctions in rat models of hypothyroidism.
J Appl Toxicol
; 36(1): 24-34, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25825206
9.
Cuprizone decreases intermediate and late-stage progenitor cells in hippocampal neurogenesis of rats in a framework of 28-day oral dose toxicity study.
Toxicol Appl Pharmacol
; 287(3): 210-21, 2015 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26057786
10.
Gene expression profile of brain regions reflecting aberrations in nervous system development targeting the process of neurite extension of rat offspring exposed developmentally to glycidol.
J Appl Toxicol
; 34(12): 1389-99, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24395379
11.
[Transcriptomics-driven Evaluation on Liver Toxicity Using Adverse Outcome Pathways (AOP)].
Yakugaku Zasshi
; 140(4): 491-498, 2020.
Artigo
em Japonês
| MEDLINE | ID: mdl-32238630
12.
Twenty-eight-day repeated oral doses of sodium valproic acid increases neural stem cells and suppresses differentiation of granule cell lineages in adult hippocampal neurogenesis of postpubertal rats.
Toxicol Lett
; 312: 195-203, 2019 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31085223
13.
Expression Characteristics of Genes Hypermethylated and Downregulated in Rat Liver Specific to Nongenotoxic Hepatocarcinogens.
Toxicol Sci
; 169(1): 122-136, 2019 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30690589
14.
Relationship between the results of in vitro receptor binding assay to human estrogen receptor alpha and in vivo uterotrophic assay: comparative study with 65 selected chemicals.
Toxicol In Vitro
; 22(1): 225-31, 2008 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-17904329
15.
Erratum to: The OECD validation program of the H295R steroidogenesis assay: Phase 3. Final inter-laboratory validation study.
Environ Sci Pollut Res Int
; 25(15): 15265-15267, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29079977
16.
Differential effects between developmental and postpubertal exposure to N-methyl-N-nitrosourea on progenitor cell proliferation of rat hippocampal neurogenesis in relation to COX2 expression in granule cells.
Toxicology
; 389: 55-66, 2017 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28688903
17.
Maternal Exposure to Valproic Acid Primarily Targets Interneurons Followed by Late Effects on Neurogenesis in the Hippocampal Dentate Gyrus in Rat Offspring.
Neurotox Res
; 31(1): 46-62, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27566479
18.
Simpler alternative to CARCINOscreen(®) based on quantitative PCR (qPCR).
J Toxicol Sci
; 41(3): 383-90, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27193730
19.
Immunohistochemistry of aberrant neuronal development induced by 6-propyl-2-thiouracil in rats.
Toxicol Lett
; 261: 59-71, 2016 Nov 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27553673
20.
Developmental exposure to cuprizone reduces intermediate-stage progenitor cells and cholinergic signals in the hippocampal neurogenesis in rat offspring.
Toxicol Lett
; 234(3): 180-93, 2015 May 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-25704630