Detalhe da pesquisa
1.
Exploring chromone sulfonamides and sulfonylhydrazones as highly selective ectonucleotidase inhibitors: Synthesis, biological evaluation and in silico study.
Bioorg Chem
; 134: 106450, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36924652
2.
Deep eutectic solvent mediated synthesis of 3,4-dihydropyrimidin-2(1H)-ones and evaluation of biological activities targeting neurodegenerative disorders.
Bioorg Chem
; 118: 105457, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34798458
3.
Synthesis, In-vitro evaluation and molecular docking studies of oxoindolin phenylhydrazine carboxamides as potent and selective inhibitors of ectonucleoside triphosphate diphosphohydrolase (NTPDase).
Bioorg Chem
; 112: 104957, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34020240
4.
Synthesis of imidazole-pyrazole conjugates bearing aryl spacer and exploring their enzyme inhibition potentials.
Bioorg Chem
; 108: 104686, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33581666
5.
Identification of NSAIDs as lipoxygenase inhibitors through highly sensitive chemiluminescence method, expression analysis in mononuclear cells and computational studies.
Bioorg Chem
; 110: 104818, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33784531
6.
Probing phenylcarbamoylazinane-1,2,4-triazole amides derivatives as lipoxygenase inhibitors along with cytotoxic, ADME and molecular docking studies.
Bioorg Chem
; 107: 104525, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33317840
7.
Synthesis of benzimidazole based hydrazones as non-sugar based α-glucosidase inhibitors: Structure activity relation and molecular docking.
Drug Dev Res
; 82(7): 1033-1043, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33665884
8.
Probing 2-acetylbenzofuran hydrazones and their metal complexes as α-glucosidase inhibitors.
Bioorg Chem
; 102: 104082, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32717690
9.
4-Oxycoumarinyl linked acetohydrazide Schiff bases as potent urease inhibitors.
Bioorg Chem
; 105: 104365, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33091669
10.
Synthesis of new indazole based dual inhibitors of α-glucosidase and α-amylase enzymes, their in vitro, in silico and kinetics studies.
Bioorg Chem
; 94: 103195, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31451297
11.
Evaluation of sulfonate and sulfamate derivatives possessing benzofuran or benzothiophene nucleus as inhibitors of nucleotide pyrophosphatases/phosphodiesterases and anticancer agents.
Bioorg Chem
; 104: 104305, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33017718
12.
Sulfonylhydrazones: Design, synthesis and investigation of ectonucleotidase (ALP & e5'NT) inhibition activities.
Bioorg Chem
; 100: 103827, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32402802
13.
A Novel Sulfonamide, 4-FS, Reduces Ethanol Drinking and Physical Withdrawal Associated With Ethanol Dependence.
Int J Mol Sci
; 21(12)2020 Jun 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32575871
14.
Acridine-based (thio)semicarbazones and hydrazones: Synthesis, in vitro urease inhibition, molecular docking and in-silico ADME evaluation.
Bioorg Chem
; 82: 6-16, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30267972
15.
Imidazole-pyrazole hybrids: Synthesis, characterization and in-vitro bioevaluation against α-glucosidase enzyme with molecular docking studies.
Bioorg Chem
; 82: 267-273, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30396060
16.
Exploring antidiabetic potential of adamantyl-thiosemicarbazones via aldose reductase (ALR2) inhibition.
Bioorg Chem
; 92: 103244, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31541804
17.
Benzoxazinone-thiosemicarbazones as antidiabetic leads via aldose reductase inhibition: Synthesis, biological screening and molecular docking study.
Bioorg Chem
; 87: 857-866, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30551808
18.
Evaluation of α-glucosidase inhibiting potentials with docking calculations of synthesized arylidene-pyrazolones.
Bioorg Chem
; 77: 507-514, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29454828
19.
Semicarbazone derivatives as urease inhibitors: Synthesis, biological evaluation, molecular docking studies and in-silico ADME evaluation.
Bioorg Chem
; 79: 19-26, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29709568
20.
Green synthesis, inhibition studies of yeast α-glucosidase and molecular docking of pyrazolylpyridazine amines.
Bioorg Chem
; 71: 170-180, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28259376