Detalhe da pesquisa
1.
Aberrant Activation of Notch1 Signaling in Glomerular Endothelium Induces Albuminuria.
Circ Res
; 128(5): 602-618, 2021 03 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33435713
2.
Integrating a phenotypic screening with a structural simplification strategy to identify 4-phenoxy-quinoline derivatives to potently disrupt the mitotic localization of Aurora kinase B.
Bioorg Med Chem
; 80: 117173, 2023 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36696874
3.
The Phytochemical Scoulerine Inhibits Aurora Kinase Activity to Induce Mitotic and Cytokinetic Defects.
J Nat Prod
; 84(8): 2312-2320, 2021 08 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-34406008
4.
The anti-apoptotic proteins Bcl-2 and Bcl-xL suppress Beclin 1/Atg6-mediated lethal autophagy in polyploid cells.
Exp Cell Res
; 394(1): 112112, 2020 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32473226
5.
Notch1 activates angiogenic regulator Netrin4 in endothelial cells.
J Cell Mol Med
; 23(5): 3762-3766, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30784178
6.
Metabolic reprogramming and Notch activity distinguish between non-small cell lung cancer subtypes.
Br J Cancer
; 121(1): 51-64, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31114017
7.
Dihydroartemisinin up-regulates VE-cadherin expression in human renal glomerular endothelial cells.
J Cell Mol Med
; 22(3): 2028-2032, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29193726
8.
Trichostatin A suppresses lung adenocarcinoma development in Grg1 overexpressing transgenic mice.
Biochem Biophys Res Commun
; 463(4): 1230-6, 2015 Aug 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-26086099
9.
Cadmium induces vascular permeability via activation of the p38 MAPK pathway.
Biochem Biophys Res Commun
; 450(1): 447-52, 2014 Jul 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-24909688
10.
In-vitro metabolism of LXY18, an orally available, potent blocker of AURKB relocation in mitosis.
J Pharm Biomed Anal
; 232: 115415, 2023 Aug 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37120975
11.
The Aurora kinase B relocation blocker LXY18 triggers mitotic catastrophe selectively in malignant cells.
PLoS One
; 18(10): e0293283, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37903144
12.
Orally Bioavailable 4-Phenoxy-quinoline Compound as a Potent Aurora Kinase B Relocation Blocker for Cancer Treatment.
ACS Pharmacol Transl Sci
; 6(8): 1155-1163, 2023 Aug 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37588758
13.
The phytochemical, corynoline, diminishes Aurora kinase B activity to induce mitotic defect and polyploidy.
Biomed Pharmacother
; 147: 112645, 2022 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-35051862
14.
A high-content screen identifies the vulnerability of MYC-overexpressing cells to dimethylfasudil.
PLoS One
; 16(3): e0248355, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33760847
15.
CD109 is specifically expressed in endothelial cells of cutaneous cavernous haemangioma.
Histopathology
; 67(1): 133-5, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25388101
16.
Dihydroartemisinin ameliorates sepsis-induced hyperpermeability of glomerular endothelium via up-regulation of occludin expression.
Biomed Pharmacother
; 99: 313-318, 2018 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-29353206
17.
GATA3-induced vWF upregulation in the lung adenocarcinoma vasculature.
Oncotarget
; 8(66): 110517-110529, 2017 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29299165
18.
Plasma von Willebrand factor level is transiently elevated in a rat model of acute myocardial infarction.
Exp Ther Med
; 10(5): 1743-1749, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26640545
19.
Postnatal Notch1 activation induces Tcell malignancy in conditional and inducible mouse models.
Int J Oncol
; 45(5): 1997-2004, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25175815
20.
Dihydroartemisinin inhibits vascular endothelial growth factor-induced endothelial cell migration by a p38 mitogen-activated protein kinase-independent pathway.
Exp Ther Med
; 8(6): 1707-1712, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25371719