Detalhe da pesquisa
1.
Alternative boronic acids in the detection of Mycolactone A/B using the thin layer chromatography (f-TLC) method for diagnosis of Buruli ulcer.
BMC Infect Dis
; 23(1): 495, 2023 Jul 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-37501134
2.
Synthesis and profiling of benzylmorpholine 1,2,4,5-tetraoxane analogue N205: Towards tetraoxane scaffolds with potential for single dose cure of malaria.
Bioorg Med Chem
; 26(11): 2996-3005, 2018 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29779669
3.
Generation of quinolone antimalarials targeting the Plasmodium falciparum mitochondrial respiratory chain for the treatment and prophylaxis of malaria.
Proc Natl Acad Sci U S A
; 109(21): 8298-303, 2012 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-22566611
4.
Synthesis and evaluation of the antimalarial, anticancer, and caspase 3 activities of tetraoxane dimers.
Bioorg Med Chem
; 21(23): 7392-7, 2013 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24148834
5.
Inhibiting Leishmania donovani Sterol Methyltransferase to Identify Lead Compounds Using Molecular Modelling.
Pharmaceuticals (Basel)
; 16(3)2023 Feb 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36986430
6.
Correction: Antischistosomal, antionchocercal and antitrypanosomal potentials of some Ghanaian traditional medicines and their constituents.
PLoS Negl Trop Dis
; 17(1): e0011044, 2023 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-36598927
7.
Evaluation of the fluorescent-thin layer chromatography (f-TLC) for the diagnosis of Buruli ulcer disease in Ghana.
PLoS One
; 17(8): e0270235, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35917367
8.
Homology Modeling, de Novo Design of Ligands, and Molecular Docking Identify Potential Inhibitors of Leishmania donovani 24-Sterol Methyltransferase.
Front Cell Infect Microbiol
; 12: 859981, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35719359
9.
Targeting the Ubiquinol-Reduction (Qi) Site of the Mitochondrial Cytochrome bc1 Complex for the Development of Next Generation Quinolone Antimalarials.
Biology (Basel)
; 11(8)2022 Jul 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35892964
10.
Unravelling the myth surrounding sterol biosynthesis as plausible target for drug design against leishmaniasis.
J Parasit Dis
; 45(4): 1152-1171, 2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-34790000
11.
The Search for Putative Hits in Combating Leishmaniasis: The Contributions of Natural Products Over the Last Decade.
Nat Prod Bioprospect
; 11(5): 489-544, 2021 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-34260050
12.
Antischistosomal, antionchocercal and antitrypanosomal potentials of some Ghanaian traditional medicines and their constituents.
PLoS Negl Trop Dis
; 14(12): e0008919, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33382717
13.
Setting Our Sights on Infectious Diseases.
ACS Infect Dis
; 6(1): 3-13, 2020 01 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31808676
14.
A tetraoxane-based antimalarial drug candidate that overcomes PfK13-C580Y dependent artemisinin resistance.
Nat Commun
; 8: 15159, 2017 05 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-28537265
15.
Identification of a 1,2,4,5-tetraoxane antimalarial drug-development candidate (RKA 182) with superior properties to the semisynthetic artemisinins.
Angew Chem Int Ed Engl
; 49(33): 5693-7, 2010 Aug 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-20629058
16.
An endoperoxide-based hybrid approach to deliver falcipain inhibitors inside malaria parasites.
ChemMedChem
; 8(9): 1528-36, 2013 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-23853126
17.
Identification of novel antimalarial chemotypes via chemoinformatic compound selection methods for a high-throughput screening program against the novel malarial target, PfNDH2: increasing hit rate via virtual screening methods.
J Med Chem
; 55(7): 3144-54, 2012 Apr 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-22380711
18.
Comparison of the reactivity of antimalarial 1,2,4,5-tetraoxanes with 1,2,4-trioxolanes in the presence of ferrous iron salts, heme, and ferrous iron salts/phosphatidylcholine.
J Med Chem
; 54(19): 6443-55, 2011 Oct 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-21888440
19.
Endoperoxide carbonyl falcipain 2/3 inhibitor hybrids: toward combination chemotherapy of malaria through a single chemical entity.
J Med Chem
; 53(22): 8202-6, 2010 Nov 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-20979352
20.
Antimalarial mannoxanes: hybrid antimalarial drugs with outstanding oral activity profiles and a potential dual mechanism of action.
ChemMedChem
; 6(8): 1357-61, 2011 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21692184