Detalhe da pesquisa
1.
Application of Accelerator Mass Spectrometry to Characterize the Mass Balance Recovery and Disposition of AZD4831, a Novel Myeloperoxidase Inhibitor, following Administration of an Oral Radiolabeled Microtracer Dose in Humans.
Drug Metab Dispos
; 51(4): 451-463, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36639243
2.
Functionality of primary hepatic non-parenchymal cells in a 3D spheroid model and contribution to acetaminophen hepatotoxicity.
Arch Toxicol
; 94(4): 1251-1263, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32112222
3.
Integrated in vitro models for hepatic safety and metabolism: evaluation of a human Liver-Chip and liver spheroid.
Arch Toxicol
; 93(4): 1021-1037, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30915487
4.
Multiple compound-related adverse properties contribute to liver injury caused by endothelin receptor antagonists.
J Pharmacol Exp Ther
; 352(2): 281-90, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25467130
5.
Reproducing human and cross-species drug toxicities using a Liver-Chip.
Sci Transl Med
; 11(517)2019 11 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31694927
6.
Critical differences in drug metabolic properties of human hepatic cellular models, including primary human hepatocytes, stem cell derived hepatocytes, and hepatoma cell lines.
Biochem Pharmacol
; 155: 124-140, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29953844