Detalhe da pesquisa
1.
Expansion of T memory stem cells with superior anti-tumor immunity by Urolithin A-induced mitophagy.
Immunity
; 55(11): 2059-2073.e8, 2022 11 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36351375
2.
Systems genetics of metabolism: the use of the BXD murine reference panel for multiscalar integration of traits.
Cell
; 150(6): 1287-99, 2012 Sep 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-22939713
3.
MicroRNA-382 silencing induces a mitonuclear protein imbalance and activates the mitochondrial unfolded protein response in muscle cells.
J Cell Physiol
; 234(5): 6601-6610, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30417335
4.
An evolutionarily conserved role for the aryl hydrocarbon receptor in the regulation of movement.
PLoS Genet
; 10(9): e1004673, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-25255223
5.
Genetically altering organismal metabolism by leptin-deficiency benefits a mouse model of amyotrophic lateral sclerosis.
Hum Mol Genet
; 23(18): 4995-5008, 2014 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24833719
6.
Bioavailable copper modulates oxidative phosphorylation and growth of tumors.
Proc Natl Acad Sci U S A
; 110(48): 19507-12, 2013 Nov 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-24218578
7.
Direct supplementation with Urolithin A overcomes limitations of dietary exposure and gut microbiome variability in healthy adults to achieve consistent levels across the population.
Eur J Clin Nutr
; 76(2): 297-308, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34117375
8.
Urolithin A improves mitochondrial health, reduces cartilage degeneration, and alleviates pain in osteoarthritis.
Aging Cell
; 21(8): e13662, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35778837
9.
Urolithin A improves muscle strength, exercise performance, and biomarkers of mitochondrial health in a randomized trial in middle-aged adults.
Cell Rep Med
; 3(5): 100633, 2022 05 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35584623
10.
Impact of the Natural Compound Urolithin A on Health, Disease, and Aging.
Trends Mol Med
; 27(7): 687-699, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34030963
11.
Urolithin A improves muscle function by inducing mitophagy in muscular dystrophy.
Sci Transl Med
; 13(588)2021 04 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33827972
12.
ARDD 2020: from aging mechanisms to interventions.
Aging (Albany NY)
; 12(24): 24484-24503, 2020 12 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-33378272
13.
Publisher Correction: Mitochondrial function is impaired in the skeletal muscle of pre-frail elderly.
Sci Rep
; 9(1): 17821, 2019 Nov 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-31767924
14.
The mitophagy activator urolithin A is safe and induces a molecular signature of improved mitochondrial and cellular health in humans.
Nat Metab
; 1(6): 595-603, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32694802
15.
Mitochondrial function is impaired in the skeletal muscle of pre-frail elderly.
Sci Rep
; 8(1): 8548, 2018 06 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29867098
16.
Safety assessment of Urolithin A, a metabolite produced by the human gut microbiota upon dietary intake of plant derived ellagitannins and ellagic acid.
Food Chem Toxicol
; 108(Pt A): 289-297, 2017 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-28757461
17.
An unbiased silencing screen in muscle cells identifies miR-320a, miR-150, miR-196b, and miR-34c as regulators of skeletal muscle mitochondrial metabolism.
Mol Metab
; 6(11): 1429-1442, 2017 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-29107290
18.
Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents.
Nat Med
; 22(8): 879-88, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27400265
19.
A method to identify and validate mitochondrial modulators using mammalian cells and the worm C. elegans.
Sci Rep
; 4: 5285, 2014 Jun 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-24923838
20.
Pharmacological approaches to restore mitochondrial function.
Nat Rev Drug Discov
; 12(6): 465-83, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23666487