Detalhe da pesquisa
1.
Heparan Sulfate Proteoglycans Biosynthesis and Post Synthesis Mechanisms Combine Few Enzymes and Few Core Proteins to Generate Extensive Structural and Functional Diversity.
Molecules
; 25(18)2020 Sep 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32937952
2.
Discovery of Alternative Producers of the Enediyne Antitumor Antibiotic C-1027 with High Titers.
J Nat Prod
; 81(3): 594-599, 2018 03 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-29345939
3.
Characterization of Intersubunit Communication in the Virginiamycin trans-Acyl Transferase Polyketide Synthase.
J Am Chem Soc
; 138(12): 4155-67, 2016 Mar 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-26982529
4.
Evaluating Ketoreductase Exchanges as a Means of Rationally Altering Polyketide Stereochemistry.
Chembiochem
; 16(9): 1357-64, 2015 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25851784
5.
Functional Characterization of Cytochrome P450 Hydroxylase YpmL in Yangpumicin A Biosynthesis and Its Application for Anthraquinone-Fused Enediyne Structural Diversification.
Org Lett
; 24(5): 1219-1223, 2022 02 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35084871
6.
Antimicrobial Bombinin-like Peptide 3 Selectively Recognizes and Inserts into Bacterial Biomimetic Bilayers in Multiple Steps.
J Med Chem
; 64(8): 5185-5197, 2021 04 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-33851832
7.
Cytochrome P450 Hydroxylase TnmL Catalyzing Sequential Hydroxylation with an Additional Proofreading Activity in Tiancimycin Biosynthesis.
ACS Chem Biol
; 16(7): 1172-1178, 2021 07 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34138533
8.
Characterization of TnmH as an O-Methyltransferase Revealing Insights into Tiancimycin Biosynthesis and Enabling a Biocatalytic Strategy To Prepare Antibody-Tiancimycin Conjugates.
J Med Chem
; 63(15): 8432-8441, 2020 08 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-32658465
9.
ADAPTABLE: a comprehensive web platform of antimicrobial peptides tailored to the user's research.
Life Sci Alliance
; 2(6)2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31740563
10.
Comparative Studies of the Biosynthetic Gene Clusters for Anthraquinone-Fused Enediynes Shedding Light into the Tailoring Steps of Tiancimycin Biosynthesis.
Org Lett
; 20(18): 5918-5921, 2018 09 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-30212211
11.
Biochemical and Structural Characterization of TtnD, a Prenylated FMN-Dependent Decarboxylase from the Tautomycetin Biosynthetic Pathway.
ACS Chem Biol
; 13(9): 2728-2738, 2018 09 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-30152678
12.
Resistance to Enediyne Antitumor Antibiotics by Sequestration.
Cell Chem Biol
; 25(9): 1075-1085.e4, 2018 09 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29937405
13.
Crystal Structure of Thioesterase SgcE10 Supporting Common Polyene Intermediates in 9- and 10-Membered Enediyne Core Biosynthesis.
ACS Omega
; 2(8): 5159-5169, 2017 Aug 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-28884166