Detalhe da pesquisa
1.
LRRK2 dynamics analysis identifies allosteric control of the crosstalk between its catalytic domains.
PLoS Biol
; 20(2): e3001427, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35192607
2.
Calculation of centralities in protein kinase A.
Proc Natl Acad Sci U S A
; 119(47): e2215420119, 2022 11 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-36375071
3.
Conformation and dynamics of the kinase domain drive subcellular location and activation of LRRK2.
Proc Natl Acad Sci U S A
; 118(23)2021 06 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34088839
4.
Germline and Mosaic Variants in PRKACA and PRKACB Cause a Multiple Congenital Malformation Syndrome.
Am J Hum Genet
; 107(5): 977-988, 2020 11 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33058759
5.
Structural analyses of the PKA RIIß holoenzyme containing the oncogenic DnaJB1-PKAc fusion protein reveal protomer asymmetry and fusion-induced allosteric perturbations in fibrolamellar hepatocellular carcinoma.
PLoS Biol
; 18(12): e3001018, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33370777
6.
Structure and mechanism of monoclonal antibody binding to the junctional epitope of Plasmodium falciparum circumsporozoite protein.
PLoS Pathog
; 16(3): e1008373, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32150583
7.
Dynamic allostery-based molecular workings of kinase:peptide complexes.
Proc Natl Acad Sci U S A
; 116(30): 15052-15061, 2019 07 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-31285328
8.
Two PKA RIα holoenzyme states define ATP as an isoform-specific orthosteric inhibitor that competes with the allosteric activator, cAMP.
Proc Natl Acad Sci U S A
; 116(33): 16347-16356, 2019 08 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-31363049
9.
A Dynamic Switch in Inactive p38γ Leads to an Excited State on the Pathway to an Active Kinase.
Biochemistry
; 58(51): 5160-5172, 2019 12 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-31794659
10.
Defining the Structural Basis for Allosteric Product Release from E. coli Dihydrofolate Reductase Using NMR Relaxation Dispersion.
J Am Chem Soc
; 139(32): 11233-11240, 2017 08 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-28737940
11.
Probing the non-native H helix translocation in apomyoglobin folding intermediates.
Biochemistry
; 53(23): 3767-80, 2014 Jun 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-24857522
12.
Molecular-dynamics simulation methods for macromolecular crystallography.
Acta Crystallogr D Struct Biol
; 79(Pt 1): 50-65, 2023 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36601807
13.
Biarsenical-tetracysteine motif as a fluorescent tag for detection in capillary electrophoresis.
Anal Chem
; 80(14): 5358-66, 2008 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18522433
14.
NMR Characterization of Information Flow and Allosteric Communities in the MAP Kinase p38γ.
Sci Rep
; 6: 28655, 2016 06 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-27353957
15.
X-ray diffraction analysis of a crystal of HscA from Escherichia coli.
Acta Crystallogr Sect F Struct Biol Cryst Commun
; 61(Pt 7): 715-7, 2005 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16511138
16.
Accurate scoring of non-uniform sampling schemes for quantitative NMR.
J Magn Reson
; 246: 31-5, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-25063954
17.
Broadening cell selection criteria with micropallet arrays of adherent cells.
Cytometry A
; 71(10): 866-74, 2007 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-17559133