Hepatic vein migration of a totally implantable venous access port-a-cath for chemotherapy in a breast carcinoma patient: case report.

A totally implantable venous access port (TIVAP) is used for chemotherapy administration. Venous port migration to the systemic circulation occurs in less than 1% of complications. The aim of this study is to describe a case of TIVAP migration to the hepatic vein. A 44-year-old female patient with breast cancer was prescribed neoadjuvant chemotherapy. A port-a-cath was surgically implanted for chemotherapy. During the port puncture procedure, blood returned normally when aspirated. When the port was first accessed and flushed with saline solution, swelling was observed at the port site and blood could no longer be aspirated. A chest radiography showed catheter embolization in the region of the hepatic vein. The catheter was retrieved using a snare technique (without complications) and the patient was discharged the next day. The care team should be alert to possible TIIVAP malfunction.

Evaluation of Spin Columns for Human Plasma Depletion to Facilitate MS-Based Proteomics Analysis of Plasma.

High abundant protein depletion is a common strategy applied to increase analytical depth in global plasma proteomics experiment setups. The standard strategies for depletion of the highest abundant proteins currently rely on multiple-use HPLC columns or multiple-use spin columns. Here we evaluate the performance of single-use spin columns for plasma depletion and show that the single-use spin reduces handling time by allowing parallelization and is easily adapted to a nonspecialized lab environment without reducing the high plasma proteome coverage and reproducibility. In addition, we evaluate the effect of viral heat inactivation on the plasma proteome, an additional step in the plasma preparation workflow that allows the sample preparation of SARS-Cov2-infected samples to be performed in a BSL3 laboratory, and report the advantage of performing the heat inactivation postdepletion. We further show the possibility of expanding the use of the depletion column cross-species to macaque plasma samples. In conclusion, we report that single-use spin columns for high abundant protein depletion meet the requirements for reproducibly in in-depth plasma proteomics and can be applied on a common animal model while also reducing the sample handling time.

Comprehensive proteomics and meta-analysis of COVID-19 host response.

COVID-19 is characterised by systemic immunological perturbations in the human body, which can lead to multi-organ damage. Many of these processes are considered to be mediated by the blood. Therefore, to better understand the systemic host response to SARS-CoV-2 infection, we performed systematic analyses of the circulating, soluble proteins in the blood through global proteomics by mass-spectrometry (MS) proteomics. Here, we show that a large part of the soluble blood proteome is altered in COVID-19, among them elevated levels of interferon-induced and proteasomal proteins. Some proteins that have alternating levels in human cells after a SARS-CoV-2 infection in vitro and in different organs of COVID-19 patients are deregulated in the blood, suggesting shared infection-related changes.The availability of different public proteomic resources on soluble blood proteome alterations leaves uncertainty about the change of a given protein during COVID-19. Hence, we performed a systematic review and meta-analysis of MS global proteomics studies of soluble blood proteomes, including up to 1706 individuals (1039 COVID-19 patients), to provide concluding estimates for the alteration of 1517 soluble blood proteins in COVID-19. Finally, based on the meta-analysis we developed CoViMAPP, an open-access resource for effect sizes of alterations and diagnostic potential of soluble blood proteins in COVID-19, which is publicly available for the research, clinical, and academic community.

Migração para veia hepática de cateter totalmente implantável para quimioterapia em paciente com carcinoma de mama: relato de caso / Hepatic vein migration of a totally implantable venous access port-a-cath for chemotherapy in a breast carcinoma patient: case report

Resumo O cateter totalmente implantável (CTI) é utilizado na administração da quimioterapia. Em menos de 1% dos casos de complicação, pode ocorrer migração do CTI para quimioterapia para a circulação sistêmica. O objetivo deste estudo foi descrever um caso de migração do CTI para a veia hepática. Uma paciente do sexo feminino, de 44 anos de idade, teve diagnóstico de câncer de mama com indicação de quimioterapia neoadjuvante. Realizou-se a implantação de cateter port-a-cath. Durante o procedimento de punção do cateter, houve retorno normal de sangue, e foi realizada infusão de soro fisiológico. Em seguida, houve um aumento de volume no local do port e não retorno de sangue à aspiração. A radiografia de tórax mostrou embolização do cateter em topografia hepática. Retirou-se o cateter pela técnica do laço (sem complicações), e a paciente recebeu alta no dia seguinte. Possíveis alterações no funcionamento do CTI devem chamar atenção da equipe responsável.

Abstract A totally implantable venous access port (TIVAP) is used for chemotherapy administration. Venous port migration to the systemic circulation occurs in less than 1% of complications. The aim of this study is to describe a case of TIVAP migration to the hepatic vein. A 44-year-old female patient with breast cancer was prescribed neoadjuvant chemotherapy. A port-a-cath was surgically implanted for chemotherapy. During the port puncture procedure, blood returned normally when aspirated. When the port was first accessed and flushed with saline solution, swelling was observed at the port site and blood could no longer be aspirated. A chest radiography showed catheter embolization in the region of the hepatic vein. The catheter was retrieved using a snare technique (without complications) and the patient was discharged the next day. The care team should be alert to possible TIIVAP malfunction.

Effect of surface treatment on the shear bond strength of a resin-based cement to porcelain.

The purpose of this in vitro study was to evaluate the effect of different surface treatments on the shear bond strength of a resin-based cement to porcelain. Sixty pairs of 50% aluminous porcelain discs were fabricated. In each pair, one disc measured 6 mm in diameter X 3 mm thickness (A) and the other measured 3 mm in diameter X 3mm thickness (B). The specimens were randomly assigned to 6 groups (n=10 pairs of discs), according to the surface treatment: etching with 10% hydrofluoric acid for 2 or 4 min (G1 and G2); 50-microm particle aluminum oxide sandblasting for 5 s (G3); sandblasting followed by etching for 2 or 4 min (G4 and G5) and control--no treatment (G6). A silane agent was applied to the treated surface of both discs of each pair. Bistite II DC dual-cure resin cement was applied and the B discs were bonded to their respective A discs. Specimens were stored in distilled water at 37 degrees C for 24 h and were tested in shear strength at a crosshead speed of 2 mm/min. Means in MPa were: G1: 14.21 +/- 4.68; G2: 8.92 +/- 3.02; G3: 10.04 +/- 2.37; G4: 12.74 +/- 5.15; G5: 10.99 +/- 3.35; G6: 6.09 +/- 1.84. Data were compared by one-way ANOVA and Tukey's test at 5% significance level. Bond strength recorded after 2-min acid etching was significantly higher than 4-min etching (p<0.05) and control (p<0.05), but did not differ significantly from sandblasting alone (p>0.05) or followed by etching for 2 or 4 min (p>0.05). Within the limitations of an in vitro study, it may be concluded that 2-min hydrofluoric acid etching produced a favorable micromechanical retention that enhanced resin cement bond strength to porcelain.

Classifying patients in peritoneal dialysis by mass spectrometry-based profiling.

Protein equalization with dithiothreitol, protein depletion with acetonitrile and the entire proteome were assessed in conjunction with matrix assisted laser desorption ionization time of flight mass spectrometry-based profiling for a fast and effective classification of patients with renal insufficiency. Two case groups were recruited as proof of concept, patients with chronic glomerulonephritis and diabetic nephropathy. Two key tools were used to develop this approach: protein concentration with centrifugal concentrator tubes with 10 KDa cut-off membranes and chemical assisted protein equalization with dithiothreitol or chemical assisted protein depletion with acetonitrile. In-house developed software was used to apply principal component analysis and hierarchical clustering to the profiles obtained. The results suggest that chemical assisted protein equalization with dithiothreitol is a methodology more robust than the other two ones, as the patients were well grouped by principal component analysis or by hierarchical clustering.

Could transformation mechanisms of acetylase-harboring pMdT1 plasmid be evaluated through proteomic tools in Escherichia coli?

UNLABELLED: Escherichia coli is a commensal microorganism of the gastrointestinal tract of animals and humans and it is an excellent model organism for the study of antibiotic resistance mechanisms. The resistance transmission and other characteristics of bacteria are based on different types of gene transfer occurring throughout the bacterial evolution. One of which is horizontal gene transfer that allows us to understand the ability of bacteria to acquire new genes. One dimensional and two dimensional electrophoresis (2-DE) techniques were performed in order to identify and characterize the proteome of two E. coli strains: Electromax DH10B, a transformation-ready strain; and TF-Se20, the Electromax DH10B that contains the aac(6')-Ib-cr4-harboring pMdT1 plasmid. After 2-DE and subsequent analysis by matrix-assisted laser desorption/ionization-time of flight mass spectrometry (MALDI-TOF MS), it was possible to identify 76 distinct proteins on the TF-Se20 strain, whereas 71 had a known function. From Electromax DH10B strain, 72 different proteins were identified of which 71 were associated with a biological process. The protein of interest, aminoglycoside N-(6')-acetyltransferase type 1, was identified by MALDI-TOF MS. The liquid chromatography-tandem mass spectrometry (LC-MS/MS) technique was performed to determine its sequence. Seventy six percent of the acetylase sequence was reconstructed only in the TF-Se20 strain, representing the single protein associated to antibiotic resistance. MALDI-TOF MS and LC-MS/MS approaches allowed us to determine the total proteome of both strains, as well as the acetylase sequence. Both of them enhance the ability to obtain more accurate information about the mechanisms of antimicrobial resistance. The pMdT1 plasmid brings a new perspective in understanding the metabolic processes that lead to antibiotic resistance. BIOLOGICAL SIGNIFICANCE: This study highlights the importance of proteomics and bioinformatics in understanding mechanisms of gene transfer and antibiotic resistance. These two approaches allow to compare the protein expression in different samples, as well as different biological processes related to each protein.

Use of MALDI-TOF mass spectrometry fingerprinting to characterize Enterococcus spp. and Escherichia coli isolates.

Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) is a faster and more accurate method to identify intact bacteria than conventional microbiology and/or molecular biology methods. The MALDI-TOF MS method is potentially applicable in diagnostic laboratories to characterize commensal bacterial species, some of which are major pathogens, from human or animal gastrointestinal tracts. The aim of this study was to analyze at the cluster and statistical level the capacity of MALDI-TOF MS to distinguish between previously characterized enterococci and Escherichia coli isolated from wild birds of the Azores archipelago. Soluble proteins were extracted from intact cell cultures of 60 isolates of Enterococcus spp. and 60 isolates of E. coli by an expedient method. MALDI-TOF MS was used to obtain 1200 mass spectra that were statistically analyzed and compared. A total of 215 distinct mass-to-charge (m/z) peaks were obtained, including a peak at m/z 4428±3, which is exclusively found in spectra from Enterococcus isolates, and peaks at m/z 5379±3 and m/z 6253±3, which are only detected in spectra from E. coli isolates. By processing mass spectra and analyzing them statistically with MassUp software, including principal component analysis (PCA) and clustering, it was possible to correctly distinguish between isolates of Enterococcus and Escherichia genera. The results of the proteomic analysis confirm that these tools could be used to characterize whole bacterial cells. In the future, with an optimized protocol for obtaining plasmid-associated proteins and the further development of bioinformatics methods, it is likely that mass peak characteristic of antimicrobial resistance will be detected, increasing the potential usefulness of MALDI-TOF in routine clinical assays. BIOLOGICAL SIGNIFICANCE: This study highlights the importance of MALDI-TOF MS in the rapid and reliable identification of bacteria by whole-cell analysis. The mass spectrometry approach performed in this study further contributes for the microbial biomarker discovery culminating in a preferable bacteria identification and antimicrobial resistance tool for the future of clinical microbiology. This article is part of a Special Issue entitled: HUPO 2014.

Shear bond strength of a ceramic to Co-Cr alloys.

STATEMENT OF PROBLEM: Different combinations of Co-Cr alloys bonded to ceramic have been used in dentistry; however, the bond strength of ceramic to metal can vary because of different compositions of these alloys. PURPOSE: The purpose of this study was to evaluate the shear bond strength of a dental ceramic to 5 commercially available Co-Cr alloys. MATERIAL AND METHODS: Five Co-Cr alloys (IPS d.SIGN 20, IPS d.SIGN 30, Remanium 2000, Heranium P, and Wirobond C) were tested and compared to a control group of an Au-Pd alloy (Olympia). Specimen disks, 5 mm high and 4 mm in diameter, were fabricated with the lost-wax technique. Sixty specimens were prepared using opaque and dentin ceramics (VITA Omega 900), veneered, 4 mm high and 4 mm in diameter, over the metal specimens (n=10). The shear bond strength test was performed in a universal testing machine with a crosshead speed of 0.5 mm/min. After shear bond testing, fracture surfaces were evaluated in a stereomicroscope under x25 magnification. Ultimate shear bond strength (MPa) data were analyzed with 1-way ANOVA and the Tukey HSD test (alpha =.05). RESULTS: The mean (SD) bond strengths (MPa) were: 61.4 (7.8) for Olympia; 94.0 (18.9) for IPS 20; 96.8 (10.2) for IPS 30; 75.1 (12.4) for Remanium; 71.2 (14.3) for Heranium P; and 63.2 (10.9) for Wirobond C. Mean bond strengths for IPS 20 and IPS 30 were not significantly different, but were significantly (P<.001) higher than mean bond strengths for the other 4 alloys, which were not significantly different from each other. CONCLUSIONS: Bond strength of a dental ceramic to a Co-Cr alloy is dependent on the alloy composition.

Micromorfologia da interface da união sistema restaurador-dentina decídua em função do sistema adesivo e do instrumento cortante rotatório / Micromorphology of the restorative system-primary dentin adhesive interface as a function of the adhesive system and rotary cutting instrument

Objetivo: Avaliar, in vitro a micromorfologia da interface da união sistema restaurador-dentina decídua, em função do sistema adesivo e do instrumento cortante rotatório. Método: Foram utilizados 20 segundos molares decíduos divididos aleatoriamente em dois grupos (n=10). No grupo C, foi realizado desgaste, até atingir a dentina, com ponta carbide. No grupo D, foi feito o mesmo desgaste, porém com ponta diamantada. A superfície preparada de cada dente foi dividida ao meio, sendo que em uma metade foi aplicado um sistema adesivo convencional de duas etapas (Single-Bond - 3M) e na outra um sistema autocondicionante de etapa única (One Up Bond F - Tokuyama). Todos os dentes foram restaurados com a resina composta híbrida (Filtek Z250 - 3M). As amostras foram termocicladas, embutidas em resina, seccionadas para obtenção da interface de união e preparadas para observação ao MEV. Resultados: Os dois sistemas adesivos utilizados foram capazes de formar camada híbrida. O sistema adesivo convencional de duas etapas proporcionou melhor selamento da interface de união, quando comparada ao autocondicionante e o emprego da ponta diamantada com o adesivo autocondicionante, mostrou o pior selamento da interface de união, com os maiores valores de gap. Conclusão: O instrumento cortante rotatório (ponta diamantada) só apresentou influência negativa na qualidade da interface sistema restaurador-dentina decídua quando se empregou sistema adesivo autocondicionante de etapa única.

Purpose: To evaluate, in vitro, the micromorphology of therestorative system-primary dentin interface as a function of theadhesive system and rotary cutting instrument.Method: Twenty primary second molars were randomly assignedto two groups (n=10). In group C, the teeth were ground with acarbide bur until reaching the dentin. In group D, the same procedurewas done however using a diamond bur. The prepared surface ofeach tooth was bisected. In one half, a 2-step total-etch adhesivesystem (Single-Bond - 3M) was applied and in the other half, a 1-step self-etching adhesive system (One Up Bond F - Tokuyama)was applied. All teeth were restored with a hybrid composite resin(Filtek Z250 - 3M). The specimens were thermocycled, embeddedin resin, sectioned to obtain the adhesive interface and preparedfor SEM analysis.Results: Both adhesive systems were capable of forming a hybridlayer. The 2-step total-etch adhesive system provided a bettersealing of the adhesive interface, in comparison to the self-etchingadhesive system. The use of a diamond bur together with the selfetchingadhesive system yielded the worst sealing of the adhesiveinterface, with presence of larger gaps.Conclusions: The rotary cutting instrument (diamond bur) had anegative influence on the quality of the restorative system-primarydentin interface only when a 1-step self-etching adhesive systemwas used.

Effect of surface treatment on the shear bond strength of a resin-based cement to porcelain

The purpose of this in vitro study was to evaluate the effect of different surface treatments on the shear bond strength of a resin-based cement to porcelain. Sixty pairs of 50 percent aluminous porcelain discs were fabricated. In each pair, one disc measured 6 mm in diameter X 3 mm thickness (A) and the other measured 3 mm in diameter X 3mm thickness (B). The specimens were randomly assigned to 6 groups (n=10 pairs of discs), according to the surface treatment: etching with 10 percent hydrofluoric acid for 2 or 4min (G1 and G2); 50-æm particle aluminum oxide sandblasting for 5 s (G3); sandblasting followed by etching for 2 or 4min (G4 and G5) and control - no treatment (G6). A silane agent was applied to the treated surface of both discs of each pair. Bistite II DC dual-cure resin cement was applied and the B discs were bonded to their respective A discs. Specimens were stored in distilled water at 37°C for 24 h and were tested in shear strength at a crosshead speed of 2 mm/min. Means in MPa were: G1: 14.21 ± 4.68; G2: 8.92 ± 3.02; G3: 10.04 ± 2.37; G4: 12.74 ± 5.15; G5: 10.99 ± 3.35; G6: 6.09 ± 1.84. Data were compared by one-way ANOVA and Tukey's test at 5 percent significance level. Bond strength recorded after 2-min acid etching was significantly higher than 4-min etching (p<0.05) and control (p<0.05), but did not differ significantlyfrom sandblasting alone (p>0.05) or followed by etching for 2 or 4 min (p>0.05). Within the limitations of an in vitro study, it may be concluded that 2-min hydrofluoric acid etching produced a favorable micromechanical retention that enhanced resin cement bond strength to porcelain.

O objetivo deste estudo in vitro foi avaliar o efeito de diferentes tratamentos de superfície na resistência ao cisalhamento da união entre porcelana e cimento resinoso. Foram confeccionados sessenta pares de discos de porcelana aluminizada a 50 por cento, de 6 mm de diâmetro por 3 mm de espessura (A) e 3 mm de diâmetro por 3 mm de espessura (B). Os espécimes foram divididos aleatoriamente em 6 grupos (n=10 pares), de acordo com os tratamentos de superfície: condicionamento com ácido fluorídrico por 2 e 4 min (G1 e G2), jateamento com óxido de alumínio (50 æm) por 5 s (G3), jateamento seguido de ácido fluorídrico por 2 e 4 min (G4 e G5) e controle (G6). Em seguida, foi aplicado silano na superfície tratada de ambos os discos, e os discos B foram cimentados sobre os respectivos discos A, utilizando o cimento resinoso dual Bistite II DC. Os espécimes foram armazenados em água destilada a 37°C por 24 h, para posterior teste de cisalhamento em máquina de ensaio universal. As médias em MPa foram: G1: 14,21 ± 4,68; G2: 8,92 ± 3,02; G3: 10,04 ± 2.37; G4: 12,74 ± 5,15; G5: 10,99 ± 3,35; G6: 6,09 ± 1,84. Os dados foram submetidos à análise de variância a um critério e teste de Tukey (p<0,05). O condicionamento ácido por 2 min apresentou resultados significantemente superiores ao condicionamento por 4 min (p<0,05) e ao grupo controle (p<0,05), porém não diferiu estatisticamente do jateamento, associado ou não ao ácido fluorídrico por 2 ou 4 min (p>0,05). Dentro das limitações de um estudo in vitro, conclui-se que o condicionamento com ácido fluorídrico por 2 min produziu uma retenção micromecânica favorável, que aumentou a resistência de união entre o cimento resinoso e a porcelana.

Resistencia adhesiva al cizallamiento de la aleación Ag-Pd a dentina de bovino / Shear bond strenght between Ag-Pd alloy and bovine dentin

El objetivo de este estudio fue evaluar el comportamiento del cemento resinoso Bistite II DC, y de los agentes de adhesión al metal MetalTite y Alloy Primer para la unión entre la aleación de Ag-Pd a dentina de bovino. Se utilizaron 30 dientes de bovinos, incluidos en una resina químicamente activada y desgastados en la superficie vestibular hasta exponer un área suficiente de dentina para realizar la cementación. Se confeccionaron cilindros a partir de la aleación Palliag M, de 3 mm de altura, 5 mm de diámetro y un alivio interno de 3 mm de diámetro con una profundidad de 40 µm. Los cilindros fueron arenados con óxido de aluminio con particulas de 50 µm, luego fueron cementados y divididos en tres grupos. En el grupo control (C) no se realizó ningun tratamiento químico sobre la superficie metálica de los cilindros. En el grupo Alloy Primer (AP) y Metal Tite (MT) el tratamiento químico de la superficie fue realizado conforme a las indicaciones de los fabricantes. Durante la cementación se aplicó una carga estática de 5 kg. Los especimenes fueron almacenados en atmósfera de 100 por ciento de humedad durante 24 horas. La prueba mecánica fue realizado en una maquina universal de ensayos mecánicos DL-1000 (EMIC-Brasil) con una célula de carga de 1000 kg a una velocidad de 1mm/minuto. Se realizó el test de Kruskal-Wallis (á?0,05), los resultados mostraron que los grupos C, MT y AP se comportaron de manera semejante al evaluar la resistencia al cizallamiento y el tipo de fractura que presentaron.

Técnica do amálgama adesivo: vantagens e desvantagens - uma revisão da literatura / Tecnic of adhesive amalgam: advantages and disadvantages - a literature review

Atualmente, a evolução dos materiais de uso odontológico e suas técnicas de utilização acontecem rapidamente. Apesar disso, por suas características, as restaurações de amálgama são ainda muito utilizadas na clínica odontológica. Com o intuito de melhorar as características dessas restaurações e ampliar seu uso na odontologia, surgiu a filosofia de Restauração de Amálgama Adesivo. O objetivo desse artigo é, por meio de uma revisão da literatura, correlacionar as vantagens e desvantagens do uso dessa técnica

Resistência à tração, de cápsulas cimentadas sobre troqueis metálicos, em função de alívio e retenção para o cimento / Tensile strength of capsules cemented on metallic dies, in function of relief and retention for the cement

O objetivo desta pesquisa foi estudar resistência à tração de cápsulas cimentadas a troqueis metálicos, com cimento fosfato de zinco, variando o alívio interno nas cápsulas e sulcos horizontais nas cápsulas e nos troqueis. Foram usinados em torno computadorizado (CNC), 288 cilindros, em aço inoxidável, simulando preparos para coroas totais (144) e respectivas coroas (144). Foram estabelecidas quarenta e oito condições experimentais, replicadas três vezes. Ajuste técnico de 2um foi feito em todas as cápsulas para permitir assentamento. As cápsulas foram divididas em três grupos iguais em função do alívio. O grupo A não foi aliviado, os grupos B e C receberam 30um e 60um respectivamente. A quantidade de sulcos variou entre zero e três, tanto nas cápsulas como nos troqueis. A profundidade dos sulcos foi de 200um. Os corpos-de-prova obtidos das cimentações com cimento fosfato de zinco foram submetidos a ensaio de tração em máquina universal de ensaios (Emic-Itaquaquecetuba-SP), no Departamento de Materiais e Tecnologia da Faculdade de Engenharia de Guaratinguetá, UNESP. Os resultados numéricos foram submetidos a tratamento estatístico (Análise de Variância e teste de Tukey). Os resultados mostraram diferença estatística significante (5 por cento), individualmente e na interação das variáveis, alívio e quantidade de sulcos nas cápsulas. Não houve diferença estatística quanto à quantidade de sulcos nos troqueis. A análise dos resultados permitiu concluir que a resistência à tração: aumentou com o aumento do alívio e com a quantidade de sulcos na cápsulas; permaneceu inalteradas com os sulcos nos troqueis; parece ser limitada pelas variáveiis estabelecidas para o troquel.

Materiais elásticos para moldagem de incrustaçöes metálicas fundidas / Elastic materials for the impression of cast metalic restaurations

Este estudo analisa os materiais de moldagem quanto à composiçäo, propriedades e técnicas com o intuito de favorecer a seleçäo de um material que atenda às necessidades clínicas

Estudo clínico comparativo entre próteses totais montadas em articuladores totalmente ajustáveis (T.T.), regulados com base na curva de compensaçäo individual e pela técnica de Hanau / Comparative clinical study between bimaxillary prosthesis mounted in fully adjustable articulators programmed either by the individual compensation curve by Hanau's technique

Foi realizada uma pesquisa clínica entre 20 próteses bimaxilares confeccionadas com base na curva individual estabelecida pelo desgaste de Paterson (A) e pela técnica das guias de mordida proposta por Hanau (B), verificando-se o número de contatos nas posiçöes de oclusäo central, trabalho, balanceio e protrusäo. Concluímos que as próteses obtidas pela técnica A apresentaram uma articulaçäo balanceada, com maior número, em todas as posiçöes mandibulares

Planejamento e desenho das próteses parciais removíveis de classe IV de Kennedy / Planning and design of the partial denture prosthesis of Kennedy's class IV

Os autores fazem consideraçöes a respeito do planejamento e desenho das próteses parciais removíveis em geral enfatizando que o correto planejamento depende da observaçäo constante, treinamento disciplinado e racional e que pela sistematizaçäo dos procedimentos pode-se chegar aos objetivos desejados. Säo apresentados e discutidos quatro planejamentos e desenhos de P.P.R. de classe IV de Kennedy segundo concepçäo clássica bem como quatros outros planejamentos para casos especiais de adolescentes

Desgaste de Paterson: análise da curva de compensação com variações na região anterior / Paterson's chew: compensating curve analysis with mandibular anterior wax occlusion modification

Neste trabalho foram avaliadas as curvas de compensação obtidas pela introdução de variáveis nos planos de cera. Para tanto, foram selecionados 10 pacientes do sexo feminino, raça branca, idade 24 a 52 anos, nos quais procedeu-se as moldagens anatômicas e funcionais, realização dos planos de cera superior e inferior ("a"), e montagem em articulador totalmente ajustável T.T. A partir destes, duas réplicas b e c foram confeccionadas e nestes realizou-se variações na região anterior do plano de cera. Nos planos de cera "a", "b" e "c" foram feitas canaletas e preenchidas com abrasivo para execução do desgaste de Paterson, para individualização das curvas de compensação. Através de uma metodologia, desenvolvida para este trabalho, foram mensuradas as variações entre as curvas de compensação.

Alginato armazenamento em cuba umificadora e tratamento de superfície / Irreversible hydrocolloids: storage time and surface treatment, concerning dimensional stability

O propósito desta investigação foi de saber entre três marcas de hidrocolóide irreversível qual delas apresentava a menor alteração dimensional tendo como variáveis o tratamento de superfície e o tempo de armazenagem

Avaliaçäo psicológica de pacientes atendidos no Centro de Oclusäo e Articulaçäo Temporo-mandibular / Psychology evaluation of patients with T.M.J. pain dysfunction syndrome attended in Occlusion Center - Säo José dos Campos, SP, Brazil

Foi realizada uma avaliaçäo psicológica de pacientes portadores de dor e disfunçäo da articulaçäo temporo-mandibular através de um trabalho integrado entre odontólogo-psicólogo, observando-se a alta freqüência de conflitos emocionais associados à disfunçäo de ATM