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1.
Nat Commun ; 6: 6864, 2015 Apr 23.
Artigo em Inglês | MEDLINE | ID: mdl-25904309

RESUMO

Many complex systems can be represented as networks consisting of distinct types of interactions, which can be categorized as links belonging to different layers. For example, a good description of the full protein-protein interactome requires, for some organisms, up to seven distinct network layers, accounting for different genetic and physical interactions, each containing thousands of protein-protein relationships. A fundamental open question is then how many layers are indeed necessary to accurately represent the structure of a multilayered complex system. Here we introduce a method based on quantum theory to reduce the number of layers to a minimum while maximizing the distinguishability between the multilayer network and the corresponding aggregated graph. We validate our approach on synthetic benchmarks and we show that the number of informative layers in some real multilayer networks of protein-genetic interactions, social, economical and transportation systems can be reduced by up to 75%.


Assuntos
Modelos Teóricos , Mapas de Interação de Proteínas , Teoria Quântica , Redes Reguladoras de Genes , Humanos , Modelos Biológicos , Modelos Econômicos , Apoio Social , Meios de Transporte
2.
Proc Natl Acad Sci U S A ; 103(12): 4352-5, 2006 Mar 21.
Artigo em Inglês | MEDLINE | ID: mdl-16537375

RESUMO

We sample a velocity field that has an inertial spectrum and a skewness that matches experimental data. In particular, we compute a self-consistent correction to the Kolmogorov exponent and find that for our model it is zero. We find that the higher-order structure functions diverge for orders larger than a certain threshold, as theorized in some recent work. The significance of the results for the statistical theory of homogeneous turbulence is reviewed.

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