Detalhe da pesquisa
1.
CXCR1 and CXCR2 Chemokine Receptor Agonists Produced by Tumors Induce Neutrophil Extracellular Traps that Interfere with Immune Cytotoxicity.
Immunity
; 52(5): 856-871.e8, 2020 05 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-32289253
2.
Antitumor efficacy and reduced toxicity using an anti-CD137 Probody therapeutic.
Proc Natl Acad Sci U S A
; 118(26)2021 06 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-34172583
3.
Focusing and sustaining the antitumor CTL effector killer response by agonist anti-CD137 mAb.
Proc Natl Acad Sci U S A
; 112(24): 7551-6, 2015 Jun 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-26034288
4.
Deciphering CD137 (4-1BB) signaling in T-cell costimulation for translation into successful cancer immunotherapy.
Eur J Immunol
; 46(3): 513-22, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26773716
5.
T cell costimulation with anti-CD137 monoclonal antibodies is mediated by K63-polyubiquitin-dependent signals from endosomes.
J Immunol
; 190(12): 6694-706, 2013 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23690480
6.
Low-dose ionizing γ-radiation elicits the extrusion of neutrophil extracellular traps.
Clin Cancer Res
; 2024 Apr 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-38630754
7.
Intratumoral neoadjuvant immunotherapy based on the BO-112 viral RNA mimetic.
Oncoimmunology
; 12(1): 2197370, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37035637
8.
Synergistic effects of combined immunotherapy strategies in a model of multifocal hepatocellular carcinoma.
Cell Rep Med
; 4(4): 101009, 2023 04 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37040772
9.
CD137 (4-1BB) requires physically associated cIAPs for signal transduction and antitumor effects.
Sci Adv
; 9(33): eadf6692, 2023 08 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37595047
10.
Intratumoral immunotherapy with mRNAs encoding chimeric protein constructs encompassing IL-12, CD137 agonists, and TGF-ß antagonists.
Mol Ther Nucleic Acids
; 33: 668-682, 2023 Sep 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37650116
11.
Intratumoral Gene Transfer of mRNAs Encoding IL12 in Combination with Decoy-Resistant IL18 Improves Local and Systemic Antitumor Immunity.
Cancer Immunol Res
; 11(2): 184-198, 2023 02 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36478221
12.
Depletion of Conventional Type-1 Dendritic Cells in Established Tumors Suppresses Immunotherapy Efficacy.
Cancer Res
; 82(23): 4373-4385, 2022 12 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36130020
13.
Two cell line models to study multiorganic metastasis and immunotherapy in lung squamous cell carcinoma.
Dis Model Mech
; 15(1)2022 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34870316
14.
Soluble CD137 as a dynamic biomarker to monitor agonist CD137 immunotherapies.
J Immunother Cancer
; 10(3)2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35236742
15.
A Therapeutically Actionable Protumoral Axis of Cytokines Involving IL-8, TNFα, and IL-1ß.
Cancer Discov
; 12(9): 2140-2157, 2022 09 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35771565
16.
Intratumoral injection of interferon-α and systemic delivery of agonist anti-CD137 monoclonal antibodies synergize for immunotherapy.
Int J Cancer
; 128(1): 105-18, 2011 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20309938
17.
CD137 (4-1BB) costimulation of CD8+ T cells is more potent when provided in cis than in trans with respect to CD3-TCR stimulation.
Nat Commun
; 12(1): 7296, 2021 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34911975
18.
In vivo depletion of DC impairs the anti-tumor effect of agonistic anti-CD137 mAb.
Eur J Immunol
; 39(9): 2424-36, 2009 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-19662633
19.
Human CD8 T cells are susceptible to TNF-mediated activation-induced cell death.
Theranostics
; 10(10): 4481-4489, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32292509
20.
Repurposing the yellow fever vaccine for intratumoral immunotherapy.
EMBO Mol Med
; 12(1): e10375, 2020 01 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31746149