Detalhe da pesquisa
1.
Saracatinib, a Selective Src Kinase Inhibitor, Blocks Fibrotic Responses in Preclinical Models of Pulmonary Fibrosis.
Am J Respir Crit Care Med
; 206(12): 1463-1479, 2022 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35998281
2.
Discovery of Clinical Candidate AZD5462, a Selective Oral Allosteric RXFP1 Agonist for Treatment of Heart Failure.
J Med Chem
; 67(6): 4419-4441, 2024 Mar 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38502782
3.
The Common H202D Variant in GDF-15 Does Not Affect Its Bioactivity but Can Significantly Interfere with Measurement of Its Circulating Levels.
J Appl Lab Med
; 7(6): 1388-1400, 2022 Oct 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-35796717
4.
High-resolution x-ray structure of human aquaporin 5.
Proc Natl Acad Sci U S A
; 105(36): 13327-32, 2008 Sep 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-18768791
5.
Repositioning of a novel GABA-B receptor agonist, AZD3355 (Lesogaberan), for the treatment of non-alcoholic steatohepatitis.
Sci Rep
; 11(1): 20827, 2021 10 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-34675338
6.
Insight into factors directing high production of eukaryotic membrane proteins; production of 13 human AQPs in Pichia pastoris.
Mol Membr Biol
; 26(4): 215-27, 2009 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-19384754
7.
Affinity tags can reduce merohedral twinning of membrane protein crystals.
Acta Crystallogr D Biol Crystallogr
; 64(Pt 11): 1183-6, 2008 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-19020358
8.
Application of High-Throughput Flow Cytometry in Early Drug Discovery: An AstraZeneca Perspective.
SLAS Discov
; 23(7): 719-731, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29787326