Detalhe da pesquisa
1.
Growing Glycans in Rosetta: Accurate de novo glycan modeling, density fitting, and rational sequon design.
PLoS Comput Biol
; 20(6): e1011895, 2024 Jun 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-38913746
2.
Massively parallel de novo protein design for targeted therapeutics.
Nature
; 550(7674): 74-79, 2017 10 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28953867
3.
Accurate de novo design of hyperstable constrained peptides.
Nature
; 538(7625): 329-335, 2016 Oct 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27626386
4.
Pseudomonas aeruginosa sabotages the generation of host proresolving lipid mediators.
Proc Natl Acad Sci U S A
; 114(1): 136-141, 2017 01 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-27980032
5.
Discovery and engineering of enhanced SUMO protease enzymes.
J Biol Chem
; 293(34): 13224-13233, 2018 08 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-29976752
6.
An epoxide hydrolase secreted by Pseudomonas aeruginosa decreases mucociliary transport and hinders bacterial clearance from the lung.
Am J Physiol Lung Cell Mol Physiol
; 314(1): L150-L156, 2018 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28982736
7.
Visualizing the Mechanism of Epoxide Hydrolysis by the Bacterial Virulence Enzyme Cif.
Biochemistry
; 55(5): 788-97, 2016 Feb 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-26752215
8.
Signature motifs identify an Acinetobacter Cif virulence factor with epoxide hydrolase activity.
J Biol Chem
; 289(11): 7460-9, 2014 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-24474692
9.
Inhibiting an Epoxide Hydrolase Virulence Factor from Pseudomonas aeruginosa Protects CFTR.
Angew Chem Int Ed Engl
; 54(34): 9881-5, 2015 Aug 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-26136396
10.
Stereochemical determinants of C-terminal specificity in PDZ peptide-binding domains: a novel contribution of the carboxylate-binding loop.
J Biol Chem
; 288(7): 5114-26, 2013 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23243314
11.
Molecular basis for the transcriptional regulation of an epoxide-based virulence circuit in Pseudomonas aeruginosa.
bioRxiv
; 2024 Jan 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38293063
12.
Simultaneous enhancement of multiple functional properties using evolution-informed protein design.
Nat Commun
; 15(1): 5141, 2024 Jun 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38902262
13.
Complete Combinatorial Mutational Enumeration of a protein functional site enables sequence-landscape mapping and identifies highly-mutated variants that retain activity.
Res Sq
; 2023 Sep 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36482980
14.
Simultaneous enhancement of multiple functional properties using evolution-informed protein design.
bioRxiv
; 2023 May 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37214973
15.
Epoxide-mediated CifR repression of cif gene expression utilizes two binding sites in Pseudomonas aeruginosa.
J Bacteriol
; 194(19): 5315-24, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22843844
16.
Analyses of the complex formation of staphylococcal enterotoxin A and the human gp130 cytokine receptor.
FEBS Lett
; 596(7): 910-923, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35060124
17.
IgG targeting distinct seasonal coronavirus- conserved SARS-CoV-2 spike subdomains correlates with differential COVID-19 disease outcomes.
Cell Rep
; 39(9): 110904, 2022 05 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-35617962
18.
Breakthroughs in computational design methods open up new frontiers for de novo protein engineering.
Protein Eng Des Sel
; 342021 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33884420
19.
Toward complete rational control over protein structure and function through computational design.
Curr Opin Struct Biol
; 66: 170-177, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33276237
20.
Biochemical and structural characterization of two cif-like epoxide hydrolases from Burkholderia cenocepacia.
Curr Res Struct Biol
; 3: 72-84, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34235487