Detalhe da pesquisa
1.
Effects of Strong Inhibition of Cytochrome P450 3A and UDP glucuronosyltransferase 1A9 and Strong Induction of Cytochrome P450 3A on the Pharmacokinetics, Safety, and Tolerability of Soticlestat: Two Drug-Drug Interaction Studies in Healthy Volunteers.
Drug Metab Dispos
; 52(3): 180-187, 2024 Feb 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38123352
2.
Comparative analytical performance of multiple plasma Aß42 and Aß40 assays and their ability to predict positron emission tomography amyloid positivity.
Alzheimers Dement
; 2022 Jul 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35820077
3.
2021 White Paper on Recent Issues in Bioanalysis: Mass Spec of Proteins, Extracellular Vesicles, CRISPR, Chiral Assays, Oligos; Nanomedicines Bioanalysis; ICH M10 Section 7.1; Non-Liquid & Rare Matrices; Regulatory Inputs (Part 1A - Recommendations on Endogenous Compounds, Small Molecules, Complex Methods, Regulated Mass Spec of Large Molecules, Small Molecule, PoC & Part 1B - Regulatory Agencies' Inputs on Bioanalysis, Biomarkers, Immunogenicity, Gene & Cell Therapy and Vaccine).
Bioanalysis
; 14(9): 505-580, 2022 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-35578993
4.
Evaluation of the Pharmacokinetics of Trazpiroben (TAK-906), a Peripherally Selective D2/D3 Dopamine Receptor Antagonist, in the Presence and Absence of Itraconazole, a Potent CYP 3A4 Inhibitor.
Clin Pharmacol
; 13: 145-155, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34285598
5.
Single-Dose Pharmacokinetics and Tolerability of the Oral Epidermal Growth Factor Receptor Inhibitor Mobocertinib (TAK-788) in Healthy Volunteers: Low-Fat Meal Effect and Relative Bioavailability of 2 Capsule Products.
Clin Pharmacol Drug Dev
; 10(9): 1028-1043, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34118178
6.
Assessment of Vedolizumab Disease-Drug-Drug Interaction Potential in Patients With Inflammatory Bowel Diseases.
Clin Pharmacol Drug Dev
; 10(7): 734-747, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33331142
7.
Identification of interspecies difference in efflux transporters of hepatocytes from dog, rat, monkey and human.
Eur J Pharm Sci
; 35(1-2): 114-26, 2008 Sep 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-18639632