Detalhe da pesquisa
1.
Peptidyl Acyloxymethyl Ketones as Activity-Based Probes for the Main Protease of SARS-CoV-2*.
Chembiochem
; 21(23): 3383-3388, 2020 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32717117
2.
Stable and Functional Rhomboid Proteases in Lipid Nanodiscs by Using Diisobutylene/Maleic Acid Copolymers.
J Am Chem Soc
; 140(44): 14557-14561, 2018 11 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30347979
3.
Benzoxazin-4-ones as novel, easily accessible inhibitors for rhomboid proteases.
Bioorg Med Chem Lett
; 28(8): 1423-1427, 2018 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29506958
4.
Towards a Novel Class of Multitarget-Directed Ligands: Dual P2X7-NMDA Receptor Antagonists.
Molecules
; 23(1)2018 Jan 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-29361735
5.
Short Total Synthesis of (±)-γ-Lycorane by a Sequential Intramolecular Acylal Cyclisation (IAC) and Intramolecular Heck Addition Reaction.
Chemistry
; 23(20): 4750-4755, 2017 Apr 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28217842
6.
Escape from adamantane: Scaffold optimization of novel P2X7 antagonists featuring complex polycycles.
Bioorg Med Chem Lett
; 27(4): 759-763, 2017 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28126517
7.
Activation pH and Gating Dynamics of Influenza A M2 Proton Channel Revealed by Single-Molecule Spectroscopy.
Angew Chem Int Ed Engl
; 56(19): 5283-5287, 2017 05 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28374543
8.
Antibacterial activity of novel benzopolycyclic amines.
Bioorg Med Chem
; 23(2): 290-6, 2015 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25515953
9.
Dimerization of pyramidalized 3,4,8,9-tetramethyltetracyclo [4.4.0.0(3,9).0(4,8)]dec-1(6)-ene to a hydrocarbon featuring four cyclohexane rings in boat conformations.
Angew Chem Int Ed Engl
; 53(31): 8195-9, 2014 Jul 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-24931126
10.
Clotrimazole-Based Modulators of the TRPM3 Ion Channel Reveal Narrow Structure-Activity Relationship.
ACS Chem Biol
; 18(3): 456-464, 2023 03 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-36762958
11.
Azapeptide activity-based probes for the SARS-CoV-2 main protease enable visualization of inhibition in infected cells.
Chem Sci
; 14(7): 1666-1672, 2023 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36819852
12.
Synthesis, In Vitro Profiling, and In Vivo Evaluation of Benzohomoadamantane-Based Ureas for Visceral Pain: A New Indication for Soluble Epoxide Hydrolase Inhibitors.
J Med Chem
; 65(20): 13660-13680, 2022 10 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-36222708
13.
Lipidomic and in-gel analysis of maleic acid co-polymer nanodiscs reveals differences in composition of solubilized membranes.
Commun Biol
; 4(1): 218, 2021 02 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33594255
14.
Isolation of intramembrane proteases in membrane-like environments.
Biochim Biophys Acta Biomembr
; 1862(4): 183193, 2020 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31945321
15.
Discovery of Cellular Roles of Intramembrane Proteases.
ACS Chem Biol
; 14(11): 2372-2388, 2019 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31287658
16.
A novel class of multitarget anti-Alzheimer benzohomoadamantaneâchlorotacrine hybrids modulating cholinesterases and glutamate NMDA receptors.
Eur J Med Chem
; 180: 613-626, 2019 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31351393
17.
Aniline-Based Inhibitors of Influenza H1N1 Virus Acting on Hemagglutinin-Mediated Fusion.
J Med Chem
; 61(1): 98-118, 2018 01 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-29220568
18.
Palladium-catalyzed cocyclotrimerization of arynes with a pyramidalized alkene.
Chem Commun (Camb)
; 54(47): 5996-5999, 2018 Jun 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29790509
19.
Slow but Steady Wins the Race: Dissimilarities among New Dual Inhibitors of the Wild-Type and the V27A Mutant M2 Channels of Influenza A Virus.
J Med Chem
; 60(9): 3727-3738, 2017 05 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28418242
20.
Heme-Regulated eIF2α Kinase Modulates Hepatic FGF21 and Is Activated by PPARß/δ Deficiency.
Diabetes
; 65(10): 3185-99, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27486236