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1.

DNA methylation signatures reveal that distinct combinations of transcription factors specify human immune cell epigenetic identity.

Roy, Roshni; Ramamoorthy, Senthilkumar; Shapiro, Benjamin D; Kaileh, Mary; Hernandez, Dena; Sarantopoulou, Dimitra; Arepalli, Sampath; Boller, Sören; Singh, Amit; Bektas, Arsun; Kim, Jaekwan; Moore, Ann Zenobia; Tanaka, Toshiko; McKelvey, Julia; Zukley, Linda; Nguyen, Cuong; Wallace, Tonya; Dunn, Christopher; Wersto, Robert; Wood, William; Piao, Yulan; Becker, Kevin G; Coletta, Christopher; De, Supriyo; Sen, Jyoti Misra; Battle, Alexis; Weng, Nan-Ping; Grosschedl, Rudolf; Ferrucci, Luigi; Sen, Ranjan.

Immunity ; 54(11): 2465-2480.e5, 2021 11 09.

Artigo em Inglês | MEDLINE | ID: mdl-34706222

2.

DNA methylation signatures reveal that distinct combinations of transcription factors specify human immune cell epigenetic identity.

Roy, Roshni; Ramamoorthy, Senthilkumar; Shapiro, Benjamin D; Kaileh, Mary; Hernandez, Dena; Sarantopoulou, Dimitra; Arepalli, Sampath; Boller, Sö Ren; Singh, Amit; Bektas, Arsun; Kim, Jaekwan; Moore, Ann Zenobia; Tanaka, Toshiko; McKelvey, Julia; Zukley, Linda; Nguyen, Cuong; Wallace, Tonya; Dunn, Christopher; Wersto, Robert; Wood, William; Piao, Yulan; Becker, Kevin G; Coletta, Christopher; De, Supriyo; Sen, Jyoti Misra; Battle, Alexis; Weng, Nan-Ping; Grosschedl, Rudolf; Ferrucci, Luigi; Sen, Ranjan.

Immunity ; 55(6): 1135, 2022 Jun 14.

Artigo em Inglês | MEDLINE | ID: mdl-35704994

3.

Transethnic associations among immune-mediated diseases and single-nucleotide polymorphisms of the aryl hydrocarbon response gene ARNT and the PTPN22 immune regulatory gene.

Schurman, Shepherd H; O'Hanlon, Terrance P; McGrath, John A; Gruzdev, Artiom; Bektas, Arsun; Xu, Hong; Garantziotis, Stavros; Zeldin, Darryl C; Miller, Frederick W.

J Autoimmun ; 107: 102363, 2020 02.

Artigo em Inglês | MEDLINE | ID: mdl-31759816

4.

A public health perspective of aging: do hyper-inflammatory syndromes such as COVID-19, SARS, ARDS, cytokine storm syndrome, and post-ICU syndrome accelerate short- and long-term inflammaging?

Bektas, Arsun; Schurman, Shepherd H; Franceschi, Claudio; Ferrucci, Luigi.

Immun Ageing ; 17: 23, 2020.

Artigo em Inglês | MEDLINE | ID: mdl-32849908

5.

Aging and Inflammation.

Singh, Amit; Schurman, Shepherd H; Bektas, Arsun; Kaileh, Mary; Roy, Roshni; Wilson, David M; Sen, Ranjan; Ferrucci, Luigi.

Cold Spring Harb Perspect Med ; 2023 Dec 05.

Artigo em Inglês | MEDLINE | ID: mdl-38052484

6.

Epigenetic signature of human immune aging in the GESTALT study.

Roy, Roshni; Kuo, Pei-Lun; Candia, Julián; Sarantopoulou, Dimitra; Ubaida-Mohien, Ceereena; Hernandez, Dena; Kaileh, Mary; Arepalli, Sampath; Singh, Amit; Bektas, Arsun; Kim, Jaekwan; Moore, Ann Z; Tanaka, Toshiko; McKelvey, Julia; Zukley, Linda; Nguyen, Cuong; Wallace, Tonya; Dunn, Christopher; Wood, William; Piao, Yulan; Coletta, Christopher; De, Supriyo; Sen, Jyoti; Weng, Nan-Ping; Sen, Ranjan; Ferrucci, Luigi.

Elife ; 122023 08 17.

Artigo em Inglês | MEDLINE | ID: mdl-37589453

7.

HiIDDD: a high-throughput imaging pipeline for the quantitative detection of DNA damage in primary human immune cells.

Gallant, Kelsey; Bektas, Arsun; Kaileh, Mary; Lustig, Ana; Ferrucci, Luigi; Pegoraro, Gianluca; Misteli, Tom.

Sci Rep ; 12(1): 6335, 2022 04 15.

Artigo em Inglês | MEDLINE | ID: mdl-35428779

8.

Does a bit of alcohol turn off inflammation and improve health?

Bektas, Arsun; Sen, Ranjan; Ferrucci, Luigi.

Age Ageing ; 45(6): 747-748, 2016 11.

Artigo em Inglês | MEDLINE | ID: mdl-27555047

9.

Age-associated changes in human CD4⁺ T cells point to mitochondrial dysfunction consequent to impaired autophagy.

Bektas, Arsun; Schurman, Shepherd H; Gonzalez-Freire, Marta; Dunn, Christopher A; Singh, Amit K; Macian, Fernando; Cuervo, Ana Maria; Sen, Ranjan; Ferrucci, Luigi.

Aging (Albany NY) ; 11(21): 9234-9263, 2019 11 09.

Artigo em Inglês | MEDLINE | ID: mdl-31707363

10.

Aging, inflammation and the environment.

Bektas, Arsun; Schurman, Shepherd H; Sen, Ranjan; Ferrucci, Luigi.

Exp Gerontol ; 105: 10-18, 2018 05.

Artigo em Inglês | MEDLINE | ID: mdl-29275161

11.

Human T cell immunosenescence and inflammation in aging.

Bektas, Arsun; Schurman, Shepherd H; Sen, Ranjan; Ferrucci, Luigi.

J Leukoc Biol ; 102(4): 977-988, 2017 10.

Artigo em Inglês | MEDLINE | ID: mdl-28733462

12.

Age-associated changes in basal NF-κB function in human CD4+ T lymphocytes via dysregulation of PI3 kinase.

Bektas, Arsun; Zhang, Yongqing; Lehmann, Elin; Wood, William H; Becker, Kevin G; Madara, Karen; Ferrucci, Luigi; Sen, Ranjan.

Aging (Albany NY) ; 6(11): 957-74, 2014 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-25553802

13.

Age-associated alterations in inducible gene transcription in human CD4+ T lymphocytes.

Bektas, Arsun; Zhang, Yongqing; Wood, William H; Becker, Kevin G; Madara, Karen; Ferrucci, Luigi; Sen, Ranjan.

Aging (Albany NY) ; 5(1): 18-36, 2013 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-23385138

14.

Marfan's syndrome.

Ho, Nicola C Y; Tran, Joseph R; Bektas, Arsun.

Lancet ; 366(9501): 1978-81, 2005 Dec 03.

Artigo em Inglês | MEDLINE | ID: mdl-16325702

15.

Klotho gene variation and expression in 20 inbred mouse strains.

Bektas, Arsun; Schurman, Shepherd H; Sharov, Alexei A; Carter, Mark G; Dietz, Harry C; Francomano, Clair A.

Mamm Genome ; 15(10): 759-67, 2004 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-15520879

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DNA methylation signatures reveal that distinct combinations of transcription factors specify human immune cell epigenetic identity.

DNA methylation signatures reveal that distinct combinations of transcription factors specify human immune cell epigenetic identity.

Transethnic associations among immune-mediated diseases and single-nucleotide polymorphisms of the aryl hydrocarbon response gene ARNT and the PTPN22 immune regulatory gene.

A public health perspective of aging: do hyper-inflammatory syndromes such as COVID-19, SARS, ARDS, cytokine storm syndrome, and post-ICU syndrome accelerate short- and long-term inflammaging?

Aging and Inflammation.

Epigenetic signature of human immune aging in the GESTALT study.

HiIDDD: a high-throughput imaging pipeline for the quantitative detection of DNA damage in primary human immune cells.

Does a bit of alcohol turn off inflammation and improve health?

Age-associated changes in human CD4⁺ T cells point to mitochondrial dysfunction consequent to impaired autophagy.

Aging, inflammation and the environment.

Human T cell immunosenescence and inflammation in aging.

Age-associated changes in basal NF-κB function in human CD4+ T lymphocytes via dysregulation of PI3 kinase.

Age-associated alterations in inducible gene transcription in human CD4+ T lymphocytes.

Marfan's syndrome.

Klotho gene variation and expression in 20 inbred mouse strains.