Detalhe da pesquisa
1.
Circulating hematopoietic stem/progenitor cell subsets contribute to human hematopoietic homeostasis.
Blood
; 143(19): 1937-1952, 2024 May 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38446574
2.
ISAnalytics enables longitudinal and high-throughput clonal tracking studies in hematopoietic stem cell gene therapy applications.
Brief Bioinform
; 24(1)2023 01 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-36545803
3.
Intrathymic AAV delivery results in therapeutic site-specific integration at TCR loci in mice.
Blood
; 141(19): 2316-2329, 2023 05 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36790505
4.
Removal of innate immune barriers allows efficient transduction of quiescent human hematopoietic stem cells.
Mol Ther
; 32(1): 124-139, 2024 Jan 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37990494
5.
Hematopoietic Tumors in a Mouse Model of X-linked Chronic Granulomatous Disease after Lentiviral Vector-Mediated Gene Therapy.
Mol Ther
; 29(1): 86-102, 2021 01 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33010230
6.
γ-TRIS: a graph-algorithm for comprehensive identification of vector genomic insertion sites.
Bioinformatics
; 36(5): 1622-1624, 2020 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31589304
7.
Intrathymic adeno-associated virus gene transfer rapidly restores thymic function and long-term persistence of gene-corrected T cells.
J Allergy Clin Immunol
; 145(2): 679-697.e5, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31513879
8.
Lentiviral haemopoietic stem-cell gene therapy in early-onset metachromatic leukodystrophy: an ad-hoc analysis of a non-randomised, open-label, phase 1/2 trial.
Lancet
; 388(10043): 476-87, 2016 Jul 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-27289174
9.
Safe and Efficient Gene Therapy for Pyruvate Kinase Deficiency.
Mol Ther
; 24(7): 1187-98, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27138040
10.
Therapeutic benefit of lentiviral-mediated neonatal intracerebral gene therapy in a mouse model of globoid cell leukodystrophy.
Hum Mol Genet
; 23(12): 3250-68, 2014 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24463623
11.
Lentiviral vector-based insertional mutagenesis identifies genes associated with liver cancer.
Nat Methods
; 10(2): 155-61, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23314173
12.
adLIMS: a customized open source software that allows bridging clinical and basic molecular research studies.
BMC Bioinformatics
; 16 Suppl 9: S5, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26051409
13.
Lentiviral vector-based insertional mutagenesis identifies genes involved in the resistance to targeted anticancer therapies.
Mol Ther
; 22(12): 2056-2068, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25195596
14.
Uncovering and dissecting the genotoxicity of self-inactivating lentiviral vectors in vivo.
Mol Ther
; 22(4): 774-85, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24441399
15.
Preclinical safety and efficacy of human CD34(+) cells transduced with lentiviral vector for the treatment of Wiskott-Aldrich syndrome.
Mol Ther
; 21(1): 175-84, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-22371846
16.
A case of T-cell acute lymphoblastic leukemia in retroviral gene therapy for ADA-SCID.
Nat Commun
; 15(1): 3662, 2024 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-38688902
17.
Lentiviral vector common integration sites in preclinical models and a clinical trial reflect a benign integration bias and not oncogenic selection.
Blood
; 117(20): 5332-9, 2011 May 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-21403130
18.
InCliniGene enables high-throughput and comprehensive in vivo clonal tracking toward clinical genomics data integration.
Database (Oxford)
; 20232023 11 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37935583
19.
Hematopoietic reconstitution dynamics of mobilized- and bone marrow-derived human hematopoietic stem cells after gene therapy.
Nat Commun
; 14(1): 3068, 2023 05 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-37244942
20.
Retrieval of vector integration sites from cell-free DNA.
Nat Med
; 27(8): 1458-1470, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34140705