Detalhe da pesquisa
1.
Beneficial effects of simultaneously targeting calorie intake and calorie efficiency in diet-induced obese mice.
Clin Sci (Lond)
; 138(4): 173-187, 2024 02 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38315575
2.
Trained innate immunity, long-lasting epigenetic modulation, and skewed myelopoiesis by heme.
Proc Natl Acad Sci U S A
; 118(42)2021 10 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-34663697
3.
Immp2l Enhances the Structure and Function of Mitochondrial Gpd2 Dehydrogenase.
Int J Mol Sci
; 25(2)2024 Jan 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38256063
4.
Investigating the Expression and Function of the Glucose Transporter GLUT6 in Obesity.
Int J Mol Sci
; 23(17)2022 Aug 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-36077188
5.
Head-to-head comparison of BAM15, semaglutide, rosiglitazone, NEN, and calorie restriction on metabolic physiology in female db/db mice.
Biochim Biophys Acta Mol Basis Dis
; 1870(1): 166908, 2024 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37793464
6.
Liver-Selective Imidazolopyrazine Mitochondrial Uncoupler SHD865 Reverses Adiposity and Glucose Intolerance in Mice.
Diabetes
; 73(3): 374-384, 2024 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37870907
7.
Oxadiazolopyridine Derivatives as Efficacious Mitochondrial Uncouplers in the Prevention of Diet-Induced Obesity.
J Med Chem
; 66(6): 3876-3895, 2023 03 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36882080
8.
Targeting negative energy balance with calorie restriction and mitochondrial uncoupling in db/db mice.
Mol Metab
; 69: 101684, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36731653
9.
Targeted delivery of a phosphoinositide 3-kinase γ inhibitor to restore organ function in sepsis.
EMBO Mol Med
; 13(10): e14436, 2021 10 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34472699
10.
Breast cancer growth and proliferation is suppressed by the mitochondrial targeted furazano[3,4-b]pyrazine BAM15.
Cancer Metab
; 9(1): 36, 2021 Oct 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34627389
11.
Mitochondrial uncoupler SHC517 reverses obesity in mice without affecting food intake.
Metabolism
; 117: 154724, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33548253
12.
Ether lipid and sphingolipid expression patterns are estrogen receptor-dependently altered in breast cancer cells.
Int J Biochem Cell Biol
; 127: 105834, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32827762
13.
Reduced Mrp2 surface availability as PI3Kγ-mediated hepatocytic dysfunction reflecting a hallmark of cholestasis in sepsis.
Sci Rep
; 10(1): 13110, 2020 08 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32753644
14.
6-Amino[1,2,5]oxadiazolo[3,4-b]pyrazin-5-ol Derivatives as Efficacious Mitochondrial Uncouplers in STAM Mouse Model of Nonalcoholic Steatohepatitis.
J Med Chem
; 63(11): 6203-6224, 2020 06 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32392051
15.
Mitochondrial uncoupler BAM15 reverses diet-induced obesity and insulin resistance in mice.
Nat Commun
; 11(1): 2397, 2020 05 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32409697
16.
PI3K signaling in the pathogenesis of obesity: The cause and the cure.
Adv Biol Regul
; 58: 1-15, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25512233
17.
Combined inhibition of PI3Kß and PI3Kγ reduces fat mass by enhancing α-MSH-dependent sympathetic drive.
Sci Signal
; 7(352): ra110, 2014 Nov 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-25406378