Detalhe da pesquisa
1.
Aberrant function of pathogenic STAT3 mutant proteins is linked to altered stability of monomers and homodimers.
Blood
; 141(12): 1411-1424, 2023 03 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36240433
2.
Targeting Janus Kinases and Signal Transducer and Activator of Transcription 3 to Treat Inflammation, Fibrosis, and Cancer: Rationale, Progress, and Caution.
Pharmacol Rev
; 72(2): 486-526, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32198236
3.
Novel STAT3 small-molecule inhibitors identified by structure-based virtual ligand screening incorporating SH2 domain flexibility.
Pharmacol Res
; 169: 105637, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33932608
4.
Impact of chronic hepatitis C virus infection on the survival of patients with oropharyngeal cancer.
Cancer
; 124(5): 960-965, 2018 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29149493
5.
Contribution of STAT3 to Inflammatory and Fibrotic Diseases and Prospects for its Targeting for Treatment.
Int J Mol Sci
; 19(8)2018 Aug 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30081609
6.
A novel role of microRNA146b in promoting mammary alveolar progenitor cell maintenance.
J Cell Sci
; 126(Pt 11): 2446-58, 2013 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23572509
7.
A novel lentiviral vector-based approach to generate chimeric antigen receptor T cells targeting Aspergillus fumigatus.
mBio
; 15(4): e0341323, 2024 Apr 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38415653
8.
Therapeutic Potential of a Small-Molecule STAT3 Inhibitor in a Mouse Model of Colitis.
Cancers (Basel)
; 15(11)2023 May 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-37296943
9.
Blockade of the PD-1/PD-L1 Immune Checkpoint Pathway Improves Infection Outcomes and Enhances Fungicidal Host Defense in a Murine Model of Invasive Pulmonary Mucormycosis.
Front Immunol
; 13: 838344, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35251033
10.
Mesothelin overexpression promotes autocrine IL-6/sIL-6R trans-signaling to stimulate pancreatic cancer cell proliferation.
Carcinogenesis
; 32(7): 1013-24, 2011 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-21515913
11.
Mesothelin confers pancreatic cancer cell resistance to TNF-α-induced apoptosis through Akt/PI3K/NF-κB activation and IL-6/Mcl-1 overexpression.
Mol Cancer
; 10: 106, 2011 Aug 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-21880146
12.
Soluble CD40 ligand induces endothelial dysfunction in human and porcine coronary artery endothelial cells.
Blood
; 112(8): 3205-16, 2008 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18658029
13.
Aberrant expression of zinc transporter ZIP4 (SLC39A4) significantly contributes to human pancreatic cancer pathogenesis and progression.
Proc Natl Acad Sci U S A
; 104(47): 18636-41, 2007 Nov 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-18003899
14.
Bempegaldesleukin selectively depletes intratumoral Tregs and potentiates T cell-mediated cancer therapy.
Nat Commun
; 11(1): 661, 2020 01 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-32005826
15.
Mesothelin-induced pancreatic cancer cell proliferation involves alteration of cyclin E via activation of signal transducer and activator of transcription protein 3.
Mol Cancer Res
; 6(11): 1755-65, 2008 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-19010822
16.
C-reactive protein inhibits cholesterol efflux from human macrophage-derived foam cells.
Arterioscler Thromb Vasc Biol
; 28(3): 519-26, 2008 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-18096828
17.
Elevated interleukin-6 and G-CSF in human pancreatic cancer cell conditioned medium suppress dendritic cell differentiation and activation.
Cancer Res
; 67(11): 5479-88, 2007 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17545630
18.
Mesothelin is a malignant factor and therapeutic vaccine target for pancreatic cancer.
Mol Cancer Ther
; 7(2): 286-96, 2008 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-18281514
19.
Correction: Small-molecule inhibition of STAT3 in radioresistant head and neck squamous cell carcinoma.
Oncotarget
; 10(16): 1603, 2019 02 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-30899429
20.
IL-6 stimulates Th2 type cytokine secretion and upregulates VEGF and NRP-1 expression in pancreatic cancer cells.
Cancer Biol Ther
; 6(7): 1096-100, 2007 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-17568185