Detalhe da pesquisa
1.
Predicting the in vivo developmental toxicity of fenarimol from in vitro toxicity data using PBTK modelling-facilitated reverse dosimetry approach.
Toxicol Appl Pharmacol
; 484: 116879, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38431230
2.
Plasma protein binding, metabolism, reaction phenotyping and toxicokinetic studies of fenarimol after oral and intravenous administration in rats.
Xenobiotica
; 51(1): 72-81, 2021 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-32660295
3.
In vitro effects of standardized extract of Bacopa monniera and its five individual active constituents on human P-glycoprotein activity.
Xenobiotica
; 45(8): 741-9, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25869246
4.
In vitro evaluation of Bacopa monniera extract and individual constituents on human recombinant monoamine oxidase enzymes.
Phytother Res
; 28(9): 1419-22, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24449518
5.
Identification of potential chemical biomarkers of hexaconazole using in vitro metabolite profiling in rat and human liver microsomes and in vivo confirmation through urinary excretion study in rats.
Chemosphere
; 358: 142123, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38677618
6.
Detection of bisphenols in Indian surface water, tap water, and packaged drinking water using dispersive liquid-liquid microextraction: exposure assessment for health risk.
Environ Sci Pollut Res Int
; 30(7): 17776-17790, 2023 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-36201081
7.
Cytochrome P450 isoforms contribution, plasma protein binding, toxicokinetics of enniatin A in rats and in vivo clearance prediction in humans.
Food Chem Toxicol
; 164: 112988, 2022 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-35398446
8.
Co-occurrence of mycotoxins: A review on bioanalytical methods for simultaneous analysis in human biological samples, mixture toxicity and risk assessment strategies.
Toxicon
; 218: 25-39, 2022 Oct 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-36049662
9.
Determination of Bisphenol Analogues in Infant Formula Products from India and Evaluating the Health Risk in Infants Asssociated with Their Exposure.
J Agric Food Chem
; 69(13): 3932-3941, 2021 Apr 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33761244
10.
Investigating the glucuronidation and sulfation pathways contribution and disposition kinetics of Bisphenol S and its metabolites using LC-MS/MS-based nonenzymatic hydrolysis method.
Chemosphere
; 273: 129624, 2021 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-33515962
11.
Insight into stereoselective disposition of enantiomers of a potent antithrombotic agent, S002-333 following administration of the racemic compound to mice.
Eur J Pharm Sci
; 101: 107-114, 2017 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28189817
12.
16-Dehydropregnenolone lowers serum cholesterol by up-regulation of CYP7A1 in hyperlipidemic male hamsters.
J Steroid Biochem Mol Biol
; 168: 110-117, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28232149
13.
Pharmacokinetic-pharmacodynamic modeling of the antihypertensive interaction between azilsartan medoxomil and chlorthalidone in spontaneously hypertensive rats.
Naunyn Schmiedebergs Arch Pharmacol
; 390(5): 457-470, 2017 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-28190245
14.
Evaluation of the impact of 16-dehydropregnenolone on the activity and expression of rat hepatic cytochrome P450 enzymes.
J Steroid Biochem Mol Biol
; 163: 183-92, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27224941
15.
Plasma pharmacokinetics, bioavailability and tissue distribution of agnuside following peroral and intravenous administration in mice using liquid chromatography tandem mass spectrometry.
J Pharm Biomed Anal
; 125: 154-64, 2016 Jun 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27018507
16.
Analysis of bacopaside I in biomatrices using liquid chromatography-tandem mass spectrometry: Pharmacokinetics and brain distribution in Swiss-albino mice.
J Pharm Biomed Anal
; 125: 101-9, 2016 Jun 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27017568
17.
Enantioselective inhibition of Cytochrome P450-mediated drug metabolism by a novel antithrombotic agent, S002-333: Major effect on CYP2B6.
Chem Biol Interact
; 256: 257-65, 2016 Aug 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-27387538
18.
A liquid chromatography-tandem mass spectrometry method for the quantitation of actarit in rabbit plasma: application to pharmacokinetics and metabolic stability.
J Mass Spectrom
; 51(1): 69-78, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26757074
19.
Pre-clinical investigation of plasma pharmacokinetics and biodistribution of a novel antithrombotic agent S002-333 in mice using LC-MS/MS.
J Chromatogr B Analyt Technol Biomed Life Sci
; 1031: 154-162, 2016 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27491065
20.
Development of an LC-MS/MS method for simultaneous determination of memantine and donepezil in rat plasma and its application to pharmacokinetic study.
J Chromatogr B Analyt Technol Biomed Life Sci
; 1001: 131-9, 2015 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26280281