Detalhe da pesquisa
1.
Recommendations on the Use of Multiple Labels in Human Mass Balance Studies.
Drug Metab Dispos
; 52(3): 153-158, 2024 Feb 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38216306
2.
Meeting report: DMDG peptide and oligonucleotide ADME workshop 2022.
Xenobiotica
; 53(4): 332-337, 2023 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-37309582
3.
Normal Neurodevelopment and Fertility in Juvenile Male Rats Exposed to Polyethylene Glycol Following Dosing With PEGylated rFIX (Nonacog Beta Pegol, N9-GP): Evidence from a 10-Week Repeat-Dose Toxicity Study.
Int J Toxicol
; 41(6): 455-475, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36036386
4.
Meeting report: 3rd workshop of the peptide ADME discussion group.
Xenobiotica
; 51(12): 1470-1474, 2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-34919491
5.
Meeting report: 2nd workshop of the peptide ADME discussion group.
Xenobiotica
; 51(1): 1-4, 2021 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-32571130
6.
Meeting report: 1st workshop of the peptide ADME discussion group.
Xenobiotica
; 51(1): 122-125, 2021 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-32048540
7.
Non-Labeled, Stable Labeled, or Radiolabelled Approaches for Provision of Intravenous Pharmacokinetics in Humans: A Discussion Piece.
Clin Pharmacol Ther
; 115(5): 931-938, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38018358
8.
New Long-Acting [89Zr]Zr-DFO GLP-1 PET Tracers with Increased Molar Activity and Reduced Kidney Accumulation.
J Med Chem
; 66(12): 7772-7784, 2023 06 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-36995126
9.
Considerations for Human ADME Strategy and Design Paradigm Shift(s) - An Industry White Paper.
Clin Pharmacol Ther
; 113(4): 775-781, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35733280
10.
Comparison of the Tissue Distribution of a Long-Circulating Glucagon-like Peptide-1 Agonist Determined by Positron Emission Tomography and Quantitative Whole-Body Autoradiography.
ACS Pharmacol Transl Sci
; 5(8): 616-624, 2022 Aug 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35990007
11.
Metabolism and excretion of the once-daily human glucagon-like peptide-1 analog liraglutide in healthy male subjects and its in vitro degradation by dipeptidyl peptidase IV and neutral endopeptidase.
Drug Metab Dispos
; 38(11): 1944-53, 2010 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-20709939
12.
Plasma Polyethylene Glycol (PEG) Levels Reach Steady State Following Repeated Treatment with N8-GP (Turoctocog Alfa Pegol; Esperoct®).
Drugs R D
; 20(2): 75-82, 2020 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-32152818
13.
Synthesis and evaluation of zirconium-89 labelled and long-lived GLP-1 receptor agonists for PET imaging.
Nucl Med Biol
; 82-83: 49-56, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32000047
14.
Investigation of a dual CD chiral CE system for separation of glitazone compounds.
Electrophoresis
; 30(16): 2853-61, 2009 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-19650045
15.
Steady-State Plasma Concentrations of Polyethylene Glycol (PEG) are Reached in Children and Adults During Once-Weekly Prophylactic Treatment with Nonacog Beta Pegol (N9-GP).
BioDrugs
; 33(6): 673-681, 2019 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-31549312
16.
Investigation of racemisation of the enantiomers of glitazone drug compounds at different pH using chiral HPLC and chiral CE.
J Pharm Biomed Anal
; 46(1): 82-7, 2008 Jan 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-17942259
17.
Absorption, metabolism and excretion of the GLP-1 analogue semaglutide in humans and nonclinical species.
Eur J Pharm Sci
; 104: 31-41, 2017 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28323117
18.
Pharmacokinetics, tissue distribution, excretion, and metabolite profiling of PEGylated rFIX (nonacog beta pegol, N9-GP) in rats.
Eur J Pharm Sci
; 92: 163-72, 2016 Sep 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27378188
19.
Pharmacokinetics, tissue distribution and excretion of 40kDa PEG and PEGylated rFVIII (N8-GP) in rats.
Eur J Pharm Sci
; 87: 58-68, 2016 May 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-26517963
20.
Chemical reactivity of the naproxen acyl glucuronide and the naproxen coenzyme A thioester towards bionucleophiles.
J Pharm Biomed Anal
; 29(1-2): 7-15, 2002 Jun 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-12062660