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1.
Turk J Med Sci ; 54(1): 121-127, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38812637

RESUMO

Background/aim: In open heart surgery, sternotomy causes inflammation in tissues, and inflammation causes postoperative pain. This study aims to examine the effects of bilateral erector spinae plane (ESP) blocks on postoperative extubation time and laboratory parameters in open heart surgery. Materials and methods: The study was managed using retrospective data from 85 patients who underwent open-heart surgery. Patients who received intravenous analgesia and were transferred to the intensive care unit with intubation were included in the study. Two groups were formed: those who received preoperative bilateral ESP block (ESB) and those nonblock (NB). Statistical significance was investigated between ESB and NB in terms of extubation time and laboratory parameters. Results: The postoperative extubation time for group NB was significantly longer at 360 (300-420) min compared to the observed 270 (240-390) min for ESB (p: 0.006). The length of stay in the intensive care unit was also longer for group NB at 4 (3-5) days compared to 3 (3-4) days for ESB (p: 0.001). Ejection fraction values, cardiopulmonary bypass, and aortic cross-clamp times were similar in both groups. Postoperative 24 h troponin I levels were higher for group NB at 0.94 (0.22-2.70) mcg/L compared to 0.16 (0.06-1.40) mcg/L for group ESB (p: 0.016). Conclusion: It would be useful for anesthesiologists to know that erector spinae plane blocks applied in the preoperative period in cardiac surgeries not only shorten the mechanical ventilation and hospitalization times but also provide lower troponin values in the postoperative period patient follow-ups.


Assuntos
Extubação , Procedimentos Cirúrgicos Cardíacos , Bloqueio Nervoso , Músculos Paraespinais , Humanos , Estudos Retrospectivos , Masculino , Feminino , Bloqueio Nervoso/métodos , Pessoa de Meia-Idade , Idoso , Músculos Paraespinais/inervação , Dor Pós-Operatória/prevenção & controle , Tempo de Internação/estatística & dados numéricos
2.
Vascular ; 30(3): 532-541, 2022 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-33977797

RESUMO

OBJECTIVES: Acupuncture is one of the oldest therapeutic interventions in the world for the treatment of pain, musculoskeletal diseases, and inflammation. This study aimed to investigate the effect of acupuncture on pain and IL-17 and IL-23 levels in the treatment of endovenous ablation. METHODS: The study was a randomized controlled trial. Patients were divided into group C (Control, n = 35) and group A (Acupuncture, n = 35). Group A patients were treated with acupuncture 24 h preoperatively. Follow-up checkups were conducted intraoperatively, postoperatively, and on the third day. RESULTS: There was no difference between men; there was a difference between women. Visual analog scale score was lower in group A at the intraoperative third and fifth minutes (0.00 vs. 1 and 0.00 vs. 0.5). Analgesic consumption was lower in group A at the end of third day (p = 0.024). Postoperative IL-17 levels were higher than preoperative levels in group A (23.58 vs. 19.33). Postoperative IL-23 levels were lower than preoperative levels in group A (13.66 vs. 29.51). Group C showed increased postoperative IL-23 levels (28.81 vs. 33.51). Preoperative IL-17 and postoperative IL-23 levels were lower in group A than in group C (19.33 vs. 27.69 and 13.66 vs. 33.51). Although no difference was observed between group A and group C in preoperative saphenous vein diameter, postoperative saphenous vein diameter was smaller in group A (p = 0.008). Saphenous vein diameter was smaller on day 3 in group A than in group C (p = 0.043). CONCLUSION: Acupuncture is effective on acute pain and level of IL-23 in the treatment of endovenous ablation using cyanoacrylate.


Assuntos
Terapia por Acupuntura , Terapia a Laser , Varizes , Insuficiência Venosa , Terapia por Acupuntura/efeitos adversos , Feminino , Humanos , Interleucina-17 , Interleucina-23 , Terapia a Laser/efeitos adversos , Masculino , Dor , Dor Pós-Operatória/diagnóstico , Dor Pós-Operatória/etiologia , Dor Pós-Operatória/prevenção & controle , Veia Safena/diagnóstico por imagem , Veia Safena/cirurgia , Resultado do Tratamento , Varizes/cirurgia , Insuficiência Venosa/terapia
3.
World J Surg ; 45(2): 507-514, 2021 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-33067685

RESUMO

BACKGROUND: It was aimed to evaluate the relationship between delta neutrophil index (DNI) and neutrophil-to-lymphocyte ratio (NLR) in the preoperative differentiation of nodular goiter and thyroid malignancy. METHODS: Patients over the age of 18 who underwent thyroid surgery between November 2014 and November 2019 were evaluated in this retrospective cohort study. Patients were divided into two groups according to their pathology results: malignant (Group M) and benign (Group B) thyroid disorders. White blood cell (WBC) count, neutrophil count, lymphocyte count, IG count and DNI were measured using an automated hematological analyzer from blood samples obtained at the preoperative period and postoperative 6th month of the follow-up. Neutrophil-to-lymphocyte ratio (NLR) values were manually calculated. Numerical data are expressed as means ± standard deviations (minimum-maximum values) or medians (minimum-maximum values) according to the normal distribution. Categorical values are expressed as percentages (%). RESULTS: A total of 243 patients (190 patients in Group B and 53 patients in Group M) who met the inclusion criteria were evaluated. The male/female ratio was 49/194. A statistically significant difference between Group M and Group B in terms of preoperative NLR, DNI and IG count was observed (p = 0.001, < 0.001 and < 0.001, respectively). No statistically significant difference was observed between the groups in terms of the control values performed in the postoperative period in terms of the NLR, DNI and IG count (p = 0.711, 0.333 and 0.714, respectively). A significant decrease was observed in the preoperative and postoperative DNIs, IG counts and NLRs in Group M (p = 0.009, < 0.001 and < 0.001, respectively). For the diagnosis of malignant thyroid diseases, the cut-off value of DNIs was ≥0.35%, and DNI sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) were 79.2%, 78.9%, 79.2% and 77.9%, respectively (area under the curve [AUC]: 0.847; confidence interval [CI]: 0.784-0.911). The cut-off value of the IG count was ≥25/mm3, and its sensitivity, specificity, PPV and NPV were 83%, 72.1%, 83%, and 72.1%, respectively (AUC: 0.847; CI: 0.784-0.911). CONCLUSION: DNI and IG counts are cheap and easily accessible tests that can be automatically calculated from automated systems without additional cost in differentiation of thyroid malignancies from benign disorders in the preoperative period.


Assuntos
Diferenciação Celular , Bócio Nodular/sangue , Linfócitos/patologia , Neutrófilos/patologia , Neoplasias da Glândula Tireoide/sangue , Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Bócio Nodular/patologia , Bócio Nodular/cirurgia , Humanos , Contagem de Leucócitos , Contagem de Linfócitos , Masculino , Pessoa de Meia-Idade , Estadiamento de Neoplasias , Prognóstico , Estudos Retrospectivos , Neoplasias da Glândula Tireoide/patologia , Neoplasias da Glândula Tireoide/cirurgia , Tireoidectomia , Carga Tumoral
4.
Childs Nerv Syst ; 36(12): 3053-3057, 2020 12.
Artigo em Inglês | MEDLINE | ID: mdl-32221655

RESUMO

Intraoperative neuromonitoring has become an increasingly commonly applied practice during surgical operations for preventing formation of neurological damage. Although it has been used on adults for a long time, the benefits and techniques of applying it in small children are not clear. We applied two different anesthesia protocols during meningomyelocele repair alongside motor-evoked potentials in a newborn and a small infant. We discussed our anesthesia management method and the effects of anesthesia on intraoperative neuromonitoring in our two very young cases in only one of which we obtained significant records.


Assuntos
Anestesia , Meningomielocele , Escoliose , Adulto , Criança , Potencial Evocado Motor , Potenciais Somatossensoriais Evocados , Humanos , Lactente , Recém-Nascido , Meningomielocele/cirurgia , Monitorização Intraoperatória , Escoliose/cirurgia
5.
J Clin Monit Comput ; 34(3): 607-614, 2020 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-32100161

RESUMO

Ultrasound-guided vascular access is a technique that can increase safety as well as technical and procedural success when performing invasive cardiovascular procedures. The aim of this study was to evaluate the effects of two cannulation techniques and vascular morphological properties on the success of femoral artery catheterisation in neonatal patients. We recruited 65 consecutive patients requiring femoral artery catheterisation and randomly divided them into two groups: Group 1, in-plane technique (n = 31) and Group 2, out-of-plane technique (n = 34). We compared the preparation duration, puncture duration, number of punctures, number of arterial punctures, number of unsuccessful interventions, hematoma incidence and vascular morphological characteristics between the groups. The mean age of Group 1 was 17.16 ± 7.04 days, and the mean age of Group 2 was 17.20 ± 7.40 days, with no difference observed between the groups (p > 0.05). Four patients in Group 1 and nine patients in Group 2 developed hematoma (p = 0.172). Hematoma was strongly correlated with the number of venous punctures (r = 0.632; p = 0.001) and the number of needle advancements (r = 0.415; p = 0.001). In terms of artery-vein position, patients whose artery overlapped the vein by > 50% required clearly longer artery cannulation durations than the other patients (p < 0.001). Although the in-plane technique has a steep learning curve, it was found superior in terms of procedure-related factors such as the number of trials, the incidence of hematoma and arterial puncture counts, as it offers advantages such as the ability to evaluate the lumen and a better control of the needle advancement direction.


Assuntos
Cateterismo Venoso Central/métodos , Artéria Femoral/diagnóstico por imagem , Veia Femoral/diagnóstico por imagem , Agulhas , Punções/métodos , Ultrassonografia de Intervenção/métodos , Ultrassonografia/métodos , Cuidados Críticos , Feminino , Humanos , Recém-Nascido , Unidades de Terapia Intensiva , Terapia Intensiva Neonatal , Masculino , Período Pré-Operatório , Estudos Prospectivos
6.
J Clin Monit Comput ; 34(4): 821-825, 2020 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-31292832

RESUMO

The aim of this study was to take ultrasonographic measurements of the length of the ligamentum flavum (LF), the LF-skin distance and the interspinous distance, which are critical for the application of neuraxial anaesthesia, with volunteers in the sitting position and with lateral tilt of the operating table at different angles to evaluate whether the target structures in neuraxial anaesthesia can be better visualised with the lateral tilt position and to determine whether or not these measurements change at different angles. The study included 29 volunteers. For the measurements, the operation table was first set into the neutral position and the length of the LF, the skin-LF distance and the interlaminar distance were measured at between L1-S1 spaces with a paramedian oblique sagittal approach with a linear ultrasound probe. Then the table was moved into 5°, 10° and 15° lateral tilt positions and the LF, LF-skin distance and the interlaminar distance were measured at the L1-S1 interspaces and recorded. At L2-3, L3-4, L4-5 and L5-S1 intervertebral interspaces, as the lateral tilt angle increased, so the measured LF length and interlaminar distance was determined to increase, this increase was statistically significant. In the ultrasonographic measurements of the skin-LF distance, at L3-4 and L4-5 intervertebral interspaces, there was a statistically significant increase. With lateral tilt applied to the table, there was determined to be an increase in ultrasonographic measurements of the LF length in the lumbar intervertebral interspaces. Therefore, for neuraxial blocks applied in the sitting position, the procedure may be facilitated with lateral tilt of the operating table.


Assuntos
Anestesia/métodos , Ligamento Amarelo/diagnóstico por imagem , Vértebras Lombares/diagnóstico por imagem , Posicionamento do Paciente , Ultrassonografia/métodos , Feminino , Humanos , Masculino , Mesas Cirúrgicas , Resultado do Tratamento , Adulto Jovem
7.
J Relig Health ; 59(6): 2935-2950, 2020 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-31776818

RESUMO

In spite of the fact that brain death during pregnancy is not a common occurrence, it is an important ethical problem for all cultures and religions can have a significant influence on the donation decision after brain death. Therefore, this study aimed to present the case of a pregnant patient developing brain death which occurred in our intensive care unit and to compare the medical, ethical and legal problems relating to pregnant cases developing brain death with 24 cases in the literature. A 21-year-old 19-week pregnant case with gestational diabetes was monitored in the anesthesia intensive care unit and developed brain death due to intracranial mass and intraventricular hemorrhage. Though brain death is a situation well understood by organ transplant professionals, brain death developing in pregnant patients still involves many medical, ethical and legal problems.


Assuntos
Morte Encefálica/diagnóstico por imagem , Neoplasias Encefálicas/complicações , Hemorragia Cerebral Intraventricular/complicações , Islamismo , Transplante de Órgãos , Doadores de Tecidos/ética , Doadores de Tecidos/legislação & jurisprudência , Obtenção de Tecidos e Órgãos , Ásia , Neoplasias Encefálicas/diagnóstico por imagem , Hemorragia Cerebral Intraventricular/diagnóstico por imagem , Ética , Europa (Continente) , Feminino , Humanos , Transplante de Órgãos/ética , Transplante de Órgãos/legislação & jurisprudência , Pacientes , Gravidez , Complicações Neoplásicas na Gravidez , Ultrassonografia , Adulto Jovem
8.
Med Sci Monit ; 24: 3531-3539, 2018 May 27.
Artigo em Inglês | MEDLINE | ID: mdl-29804126

RESUMO

BACKGROUND The aim of this study was to find a simple and easily accessible scoring system that could predict the development of sepsis in the preseptic period. MATERIAL AND METHODS The study included 161 patients with a basal sequential organ failure assessment (SOFA) value of 2 or more. The sepsis group (n=83) comprised patients with infection reported in culture results; the control group (n=78) comprised patients not showing evidence of infection in blood, urine, and phlegm cultures; samples were taken on three consecutive days. RESULTS The patients in both groups were divided into subgroups of non-survivor and survivor patients. The preseptic and septic SOFA score, neutrophil lymphocyte ratio (NLR), and procalcitonin (PRC) and lactate (Lac) values were determined to be statistically significantly higher in the sepsis group than in the control group. When the values related to sepsis were examined, a strong relationship was determined between sepsis and SOFA score, PRC values, and Lac values in the preseptic period and a weak relationship with NLR. In the model formed using multiple regression analysis with defined cutoff values for the preseptic and the septic periods, we found that in the septic period, a diagnosis of sepsis could be made with 83.8% accuracy. The diagnostic value of the same parameters evaluated in the preseptic period was 77.9%. CONCLUSIONS The diagnostic value of the combination of Lac, PRC, SOFA, and NLR were found to be similar in the preseptic period as the sepsis period; thus these combined values could safely be used for the early diagnosis of sepsis.


Assuntos
Biomarcadores/sangue , Progressão da Doença , Inflamação/sangue , Inflamação/complicações , Sepse/sangue , Sepse/complicações , Bactérias/crescimento & desenvolvimento , Líquido da Lavagem Broncoalveolar , Calcitonina/sangue , Estudos de Casos e Controles , Demografia , Humanos , Ácido Láctico/sangue , Modelos Logísticos , Contagem de Linfócitos , Linfócitos/patologia , Pessoa de Meia-Idade , Neutrófilos/patologia , Prognóstico , Curva ROC , Sepse/diagnóstico , Sepse/microbiologia , Urina/microbiologia
9.
Turk J Med Sci ; 47(5): 1583-1589, 2017 11 13.
Artigo em Inglês | MEDLINE | ID: mdl-29151336

RESUMO

Background/aim: This study was planned by considering that the use of bispectral index (BIS) monitoring ensures sufficient depth of anesthesia and avoids anesthetic awareness and patient movement in the oocyte pick-up (OPU) procedure.Materials and methods: Ninety-eight patients undergoing OPU were randomly divided into 2 groups as the control group (n = 48) and BIS group (n = 50). After propofol and remifentanil induction, the control group was given additional propofol according to reaction response, while the BIS group was given propofol at BIS values of 60 and above with the aim that BIS values be 40?60. Total procedure time, recovery time, patient movement, additional propofol consumption, total number of oocytes, and awareness during anesthesia were recorded. Results: Demographic data were similar in the two groups (P > 0.05 for all). The recovery time in the BIS group was significantly shorter compared to the control group (P < 0.001) while additional propofol consumption was found to be significantly lower (P < 0.001). Baseline BIS values fell compared to all other times after induction significantly (P < 0.001). No patient had anesthesia awareness.Conclusion: During the OPU procedure BIS monitoring is considered to prevent anesthesia awareness, intraoperative movement, and complications caused by insufficient anesthetic use as it ensures optimal doses of anesthetic agents used and early recovery.

10.
Asian Biomed (Res Rev News) ; 17(3): 136-143, 2023 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-37818162

RESUMO

Background: Postoperative pain management is an important aspect of anesthesia care and multimodal analgesic techniques are generally recommended. Objective: To compare the effect of spinal anesthesia + transversus abdominis plane (TAP) block application on postoperative analgesia quality and patient satisfaction with spinal anesthesia + intrathecal morphine (ITM) application. Methods: A total of 70 patients were randomly separated into 2 groups as spinal anesthesia + TAP block (TAP block group, n = 34) and spinal anesthesia + ITM group (ITM group, n = 36). The groups were compared in respect of age, body mass index values, and visual analog scale (VAS) values at 0 h, 2 h, 6 h, 12 h, and 18 h, and patient satisfaction was scored by Quality Improvement in Postoperative Pain Management at 24 h. Results: The mean age of the patients was 32.52 ± 6.50 years in the TAP block group and 30.11 ± 5.62 years in the ITM group, with no statistically significant difference determined. There was no statistically significant difference in terms of VAS values at 0 h, 2 h, 6 h, 12 h, and 18 h. When the factors affecting postoperative patient satisfaction were evaluated, feeling fatigue after the surgery (r = -0.811, P = 0.001) and postoperative complications such as nausea, vomiting, and itching (r = -0.831, P = 0.001) were found to have a negative effect on patient satisfaction. Conclusion: Due to low complication rates, TAP block is an effective application for postoperative analgesia management in varicocele operations that increases patient satisfaction postoperatively.

11.
Perspect Psychiatr Care ; 58(1): 61-70, 2022 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-33772802

RESUMO

PURPOSE: To determine the effect of the COVID-19 pandemic on antenatal depression in Turkish pregnant women. DESIGN AND METHODS: In this cross-sectional study, data were collected from 497 pregnant women between May and July 2020 using the Edinburgh Depression Scale (EDS) to determine the effect of obstetrics history, fear of hospitalization, concerns about the pandemic, birth, and the health of both mother and infant, on antenatal depression during the COVID-19 outbreak in Turkey. FINDINGS: The general EDS mean score of the total group was determined as mean 13.70 ± 6.22, which was higher than the critical cutoff point of 13. According to the multiple linear regression model applied in the study, the best predictive variables for the mean EDS score were determined to be concerned about completing a healthy pregnancy (r = -0.45), social media and news programs related to COVID-19 increasing levels of concern (r = -0.31), fear of hospitalization as the birth approaches (r = -0.45), having bad dreams during the COVID-19 pandemic (r = -0.41), the request for an elective cesarean delivery because of fear of catching COVID-19 (r = -0.40), fear of breastfeeding the infant (r = -0.45), and concerns that their own health would be negatively affected because of the pandemic (r = - 0.39), and these variables affected the mean EDS score negatively (total variance 40.5%, R = 0.642). PRACTICAL IMPLICATIONS: The COVID-19 pandemic has created an urgent need to implement specific antenatal programs to promote the psychological health of pregnant women and reduce antenatal depression during this or similar crises.


Assuntos
COVID-19 , Pandemias , Ansiedade , Estudos Transversais , Depressão , Feminino , Humanos , Parto , Gravidez , Gestantes , RNA Viral , SARS-CoV-2 , Estresse Psicológico , Inquéritos e Questionários , Turquia/epidemiologia
12.
Jpn J Nurs Sci ; 19(1): e12442, 2022 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-34288424

RESUMO

AIM: To determine the psychological resilience and perceived stress levels of healthcare workers in COVID-19 intensive care units. METHODS: The study was conducted with 418 physicians and nurses in Turkey between July and August 2020. The data were collected with an online survey consisting of a personal information form, the Brief Resilience Scale, and the Perceived Stress Scale. RESULTS: The study sample comprised 32.5% physicians and 67.5% nurses. Fear of transmission of COVID-19 from the patients in their care was stated by 92.6% of the physicians and 95.7% of the nurses. Almost all of the participants (99.3%) were afraid of transmitting COVID-19 to their families. The psychological resilience level of the physicians (18.42 ± 2.25) participating in the study was higher than that of the nurses (17.88 ± 2.00), and the perceived stress level was lower. It was determined that most physicians and nurses strengthened their team/work friendship bonds during the pandemic, but the motivation to work decreased. CONCLUSION: The study results suggest that frontline intensive care workers should be closely monitored as a high-risk group for psychological problems. The provision of better personal protective equipment, together with on-going monitoring and provision of psychological support, and strong family support will increase the resilience of frontline healthcare workers.


Assuntos
COVID-19 , Resiliência Psicológica , Estudos Transversais , Surtos de Doenças , Humanos , Mutação , Pandemias , SARS-CoV-2 , Estresse Psicológico/epidemiologia , Turquia
13.
Ulus Travma Acil Cerrahi Derg ; 28(7): 979-987, 2022 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-35775679

RESUMO

BACKGROUND: Although appendectomy is still a curative therapy for acute appendicitis, medical treatment has come to the fore in uncomplicated cases. This study aimed to determine the importance of immature granulocyte (IG) count and percentage for the role of medical treatment success in uncomplicated acute appendicitis. METHODS: Acute appendicitis cases were prospectively registered between July 2019 and April 2020. Using ball drawing, patients were divided into two groups as medical treatment (Group M) and undergo appendectomy (Group A). Group M was divided into two subgroups as those who responded to medical treatment medically responded (MR) and failed medical treatment (MF) within 24 h of follow-up. Changes in IG count and percentage, C-reactive protein levels, neutrophil-lymphocyte ratio, and white blood cell count between initial administration and 24th h of follow-up were examined. RESULTS: Sixty-four patients who met the inclusion criteria were followed as 31 patients in Group A and 33 in Group M. At Sub-group MF 11 patients and Subgroup MR 22 patients were followed up. At the 24th h of the follow-up, the IG count and percentage were higher in the Group MF (for IG count: Between Group A and MF, p=0.002; between Group A and Group MR, p=0.111; and between Group MR and MF, p<0.001) (for IG percentage: Between Group A and MF, p=0.001; between Group A and MR, p=0.809; and between Group MF and MR, p=0.001). This decrease in the IG count and percentage suggests that the response to medical treatment was effective [for IG count: F (148.862) = 61, p≤0.001, η2=0.707] [for IG percentage: F (10.157) = 0.252, p≤0.001, η2=0.504]. CONCLUSION: IG count and percentage are effective for evaluating the success of medical treatment of uncomplicated acute ap-pendicitis and they guide in the decision to continue medical treatment of uncomplicated acute appendicitis.


Assuntos
Apendicite , Doença Aguda , Apendicite/tratamento farmacológico , Apendicite/cirurgia , Humanos , Contagem de Leucócitos , Neutrófilos , Estudos Prospectivos
14.
Health Sci Rep ; 5(5): e752, 2022 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-35949669

RESUMO

Background and Aims: In this study, we aimed to compare the transversus abdominis plan block (TAP) and quadratus lumborum block (QL) efficacy for postoperative analgesia in patients undergoing varicocelectomy under spinal anesthesia. Methods: American Society of Anesthesiologists (ASA) 1 and 2 patients, aged 18-45 years, who underwent varicocelectomy operation under elective conditions, were included. Eighty patients were divided into three groups as TAP group, QL group, and control group by prospective randomization. The patients were operated under spinal anesthesia. At the end of the operation, TAP was applied to the TAP group with a posterior approach using ultrasound (USG) in the supine position. To the QL group, the patient was placed in the lateral decubitus position and the lateral QL was applied via USG. No block type was applied to the control group. Patient-controlled analgesia (PCA) device containing tramadol was administered intravenously at the end of the surgery in all groups. Visual analogue scale (VAS) score was questioned at 0, 2, 4, 6, 8, 10, 12, 18, 24 h in the follow-up of the patients. Intravenous 1 g paracetamol was given over VAS 4. PCA usage time and usage amounts were recorded. Results: As a result of comparing the groups according to the VAS scores at all hours were significantly different between the three groups (p < 0.001). There was a significant difference between the groups when comparing the number of PCA bolus administrations (p < 0.001). TAP and QL blocks significantly reduced the number of PCA bolus when compared with the control group (p < 0.001) but the number of PCA bolus was found to be similar between TAP and QL blocks (p > 0.05). Conclusion: TAP and QL, which are administered to evaluate the effectiveness of postoperative analgesia in patients undergoing varicocelectomy under spinal anesthesia, are both effective in reducing pain scores and the amount of analgesia consumption.

15.
Braz J Anesthesiol ; 72(1): 69-76, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-34274366

RESUMO

BACKGROUND: Cardiopulmonary bypass (CPB) causes systemic oxidative stress response and endothelial damage in systemic organs. We investigated the effects of positive end-expiratory pressure (PEEP) and mechanical ventilation (MV) applications on oxidative stress in CPB. METHODS: Seventy-one patients were recruited and 60 completed the study. Randomized groups: MV off (Group 1); MV on, tidal volume (TV) at 3-4 mL.kg-1 (Group 2); MV on, TV at 3-4 mL.kg-1, PEEP at 5 cmH2O (Group 3), n = 20 in each group. As oxidative stress markers, we used glutathione peroxidase (GPx), total antioxidant status (TAS), total oxidant status (TOS), total and native thiol (TT, NT), malondialdehyde (MDA), and catalase. We also investigated the correlation between oxidative stress and postoperative intubation time. RESULTS: The postoperative GPx levels in Group 2 were higher than Group 3 (p = 0.017). In groups 2 and 3, TAS levels were higher postoperatively than intraoperatively (p = 0.001, p = 0.019, respectively). In Group 2, the TT levels were higher postoperatively than preoperatively and intraoperatively (p = 0.008). In Group 3, the postoperative MDA levels were higher than preoperatively (p = 0.001) and were higher than both postoperative levels of Group 1 and 2 (p = 0.043, p = 0.003). As the preoperative TAS (Group 2) decreased and the postoperative NT (Group 2) and catalase (Group 3) increased, the postoperative intubation time lengthened. CONCLUSION: MV ( 3-4 mL.kg-1) alone seems to be the most advantageous strategy. Prolonged postoperative intubation time was associated with both increased NT and catalase levels.


Assuntos
Procedimentos Cirúrgicos Cardíacos , Ponte Cardiopulmonar , Antioxidantes , Catalase , Humanos , Estresse Oxidativo , Respiração Artificial
16.
J Coll Physicians Surg Pak ; 32(2): 220-225, 2022 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-35108795

RESUMO

OBJECTIVE: To determine the diagnostic value of preoperative immature granulocyte (IG) count and delta neutrophil index (DNI) level before clinical detection of axillary lymph node metastasis. STUDY DESIGN: Cohort study. PLACE AND DURATION OF STUDY: Department of General Surgery, Kahramanmaras Sutcu Imam University, Onikisubat, Turkey from February 2015 to February 2020. METHODOLOGY: Patients older than 18 years and operated for breast pathologies in the study period were evaluated retrospectively. Patients without axillary or distant organ metastasis, and who did not receive neoadjuvant chemotherapy were examined by dividing them into two groups as pathologically non-metastatic axilla (Group NM) and metastatic axilla (Group M). They were retrospectively evaluated for DNI, IG, white blood cell count (WBC), neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR) and mean platelet volumes (MPV). RESULTS: All of the 83 patients, who met the inclusion criteria, were females (100%). Forty-six patients (55.42%) were in the Group-NM and 37 (44.58%) were in Group-M. Statistically significant difference was observed between the groups in terms of WBC, NLR, PLR, MPV, DNI and IG count (p<0.05), while there was no difference in age (p = 0.862). As a result of the univariate and multivariate analysis, WBC, NLR, PLR, MPV, DNI and IG count were determined as predictive factors. The discriminatory power of the DNI for diagnosing clinically negative pathologically positive axillary metastasis of breast cancer at the cut-off value ≥0.35% (ARUC:0.903; 95% confidence interval [CI]: 0.84-0.967) showed 86.5% sensitivity, 80.4% specificity, positive predictive value (PPV) 86.5%, negative predictive value (NPV) 80.4%. The discriminatory power of the IG count for diagnosing clinically negative pathologically positive axillary metastasis of breast cancer, at the cut-off value ≥25/mm3 (ARUC:0.976; 95% CI:0.953-1.000) showed 100% sensitivity, 82.6% specificity, 100% PPV, and 82.6% NPV. CONCLUSION: DNI and IG count may be new predictive factors with high sensitivity and specificity in detecting axillary metastasis of breast cancer. Key Words: Delta neutrophil index, Immature granulocyte count, Neutrophil lymphocyte ratio, Breast cancer, Axillary metastasis.


Assuntos
Neoplasias da Mama , Neutrófilos , Estudos de Coortes , Feminino , Humanos , Contagem de Leucócitos , Metástase Linfática , Estudos Retrospectivos
17.
Ulus Travma Acil Cerrahi Derg ; 28(1): 48-56, 2022 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-34967423

RESUMO

BACKGROUND: This study aims to examine the factors affecting the selection of anaesthesia method in Fournier's gangrene. METHODS: A retrospective evaluation was made of 113 patients operated on because of Fournier's gangrene between January-May 2019. The operations were performed under spinal anaesthesia in 78 cases (Group S) and under general anaesthesia in 35 cases (Group G). The patients were evaluated regarding age, gender, the anaesthesia method used (spinal, general) anaesthetic agent applied, presence of sepsis, and biochemical, hematological and inflammatory parameters. RESULTS: When the patients were evaluated regarding the Fournier Gangrene Severity Index (FGSI), patients in Group S had lower scores (p=0.001). Examination of the tomography images revealed that in 13 (37.1%) patients, air values were seen in the right or left gluteal area, or both, extending to the subcutaneous tissue. In the evaluation of the factors affecting the selection of general anaesthesia, a positive correlation was determined between an increase in FGSI (r=0.482, p=0.001) and the presence of sepsis (r=0.485, p=0.001) and gluteal region involvement (r=0.628, p<0.001). CONCLUSION: The selection of anaesthesia method in Fournier gangrene patients is a complex process affected by factors, such as the patients' general condition, sepsis, and whether or not there is bleeding diathesis. The risk -benefit balance in the selection of anaesthesia method should be evaluated individually for patients.


Assuntos
Anestésicos , Fasciite Necrosante , Gangrena de Fournier , Gangrena de Fournier/cirurgia , Humanos , Estudos Retrospectivos , Índice de Gravidade de Doença
18.
Arch Iran Med ; 24(6): 447-452, 2021 06 01.
Artigo em Inglês | MEDLINE | ID: mdl-34488306

RESUMO

BACKGROUND: Sclerosing encapsulating peritonitis (SEP) is a rare cause of acute abdomen and can be easily misdiagnosed. Preoperative diagnosis of the SEP can be performed with preoperative imaging studies. We aimed to evaluate the clinical features of ileus cases who were diagnosed with primary or secondary SEP in the last five years. METHODS: This retrospective cohort study evaluated the patients who were admitted with ileus or acute abdomen symptoms to the Emergency Department of Elazig Training and Research Hospital and underwent surgery by the same surgical team of General Surgery Department between January 2014 and January 2019. Patients who were diagnosed with primary or secondary SEP were included. The demographic data, clinical presentation, whether the disease was primary or secondary, the treatment options performed and mortality rates were evaluated. RESULTS: SEP was observed in 11 of the patients. Ten patients underwent surgery (90.9%), and one patient (9.1%) was treated conservatively. Of the patients, six had secondary SEP (54.5%) and five had primary SEP (45.5%). In total, five patients were female (45.5%) and six were male (54.5%). The median age of the patients was 35 years (24-69). The median age of the patients with primary disease was 48 (29-69) years, while the median age of patients with secondary disease was 34.5 (24-64) years. One patient expired in the postoperative 8th hour. CONCLUSION: SEP should be considered in the case of recurrent abdominal pain attacks, especially in patients undergoing peritoneal dialysis, and it should be known that the mortality rate is high when misdiagnosed.


Assuntos
Abdome Agudo , Obstrução Intestinal , Peritonite , Abdome Agudo/etiologia , Dor Abdominal , Adulto , Idoso , Feminino , Humanos , Obstrução Intestinal/etiologia , Masculino , Pessoa de Meia-Idade , Peritonite/diagnóstico , Peritonite/etiologia , Estudos Retrospectivos , Adulto Jovem
19.
J Matern Fetal Neonatal Med ; 34(6): 960-965, 2021 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-33256477

RESUMO

OBJECTIVE: The standard treatment for patients with placenta percreta is cesarean hysterectomy that can cause severe bleeding. New-generation vessel sealing systems like LigaSure can cut and seal vascular structures and tissues. The aim of this study was to retrospectively compare hysterectomies performed with traditional instruments and those performed with LigaSure instruments to determine the possible advantages with the latter. MATERIALS AND METHODS: Patients with placenta percreta who underwent elective cesarean hysterectomy by the same surgeon were divided into two groups based on the type of instruments used. Group 1, the standard conventional hysterectomy group, operated with conventional instruments for cutting and tying; and Group 2, the LigaSure hysterectomy group, operated with the new-generation bipolar sealing and cutting instruments. The groups were retrospectively compared for bleeding, operating time, and complications. RESULTS: In Group 2, the operating time, intraoperative and total transfused erythrocyte suspension units, total fluid in the drain, and total hospital stay were lower than in Group 1 (p < .05), as was the need for internal iliac artery ligation (p = .013). The complication rates were similar between the two groups (p > .05). CONCLUSION: The use of LigaSure open instruments in cesarean hysterectomies in patients with placenta percreta may reduce operating times and the amount of bleeding.


Assuntos
Placenta Acreta , Cesárea/efeitos adversos , Feminino , Humanos , Histerectomia/efeitos adversos , Ligadura , Placenta Acreta/cirurgia , Gravidez , Estudos Retrospectivos
20.
Geriatr Gerontol Int ; 20(3): 201-205, 2020 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-31943654

RESUMO

AIM: To compare the applicability, technical difficulties and postoperative complications of surgical tracheostomy and percutaneous dilatational tracheostomy with the flexible lightwand + ultrasonography method applied because of prolonged intubation to geriatric patients in the intensive care unit. METHODS: A retrospective evaluation was made of 76 patients who received surgical tracheostomy (group 1) and 78 patients who received percutaneous dilatational tracheostomy (group 2). The patients were evaluated in respect of demographic data, duration of intubation, length of stay in the intensive care unit and discharge status, and after the intervention, the development of tube-related complications, early stage local complications and late-stage complications. RESULTS: The time from intubation to tracheostomy was determined as 22.73 ± 15.23 days in group 1 and 12.65 ± 7.64 days in group 2. The mortality rate of patients in group 1 was determined to be statistically significantly higher than that of group 2 (P = 0.048). When evaluated in respect to early and late complications, nine early- and seven late-stage complications developed in group 1, and three early- and three late-stage complications developed in group 2 (P = 0.05). In the evaluation of factors related to mortality, the time from intubation to tracheostomy (r = 0.249, P = 0.01) and the presence of a comorbidity (r = 0.325, P = 0.004) were determined to have a positive correlation with the development of mortality. CONCLUSION: Percutaneous dilatational tracheostomy with the flexible lightwand + ultrasonography technique is a safe, rapid and effective method with the advantage of management in respect to early complications, such as bleeding, and can be used safely in the geriatric patient population in intensive care conditions. Geriatr Gerontol Int 2020; ••: ••-••.


Assuntos
Intubação Intratraqueal/efeitos adversos , Complicações Pós-Operatórias/etiologia , Traqueostomia/métodos , Idoso , Idoso de 80 Anos ou mais , Cuidados Críticos , Feminino , Humanos , Unidades de Terapia Intensiva , Masculino , Estudos Retrospectivos , Turquia , Ultrassonografia
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