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1.
Knee Surg Sports Traumatol Arthrosc ; 31(4): 1299-1306, 2023 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-34458941

RESUMO

PURPOSE: Knee arthrodesis is an established procedure for limb salvage in cases of recurrent infection, total knee arthroplasty soft tissue defect, poor bone stock or a deficient extensor mechanism. Surgical options include compression plate, external fixator and arthrodesis nail. Different types of nail exist: long fusion nail, short modular nail and bridging nail. This study presents the results on knee arthrodesis using different types of intramedullary nails. The aim is to assess if a specific type of nail has a better fusion rate, clinical outcome and lower complication rate. METHODS: A mono-centric retrospective study of 48 knees arthrodesis was performed between 2000 and 2018. 15 T2™ Arthrodesis Nail, 6 OsteoBridge® Knee Arthrodesis and 27 Wichita® fusion nail were used. The mean clinic and radiological follow-up was 9.8 ± 3.8 years (2.6-18 years). RESULTS: Fusion rate was 89.6%. Time to fusion was 6.9 months. Mean Parker score was 6.9/9 points. Visual Analogic Scale was 1.9. The Wichita® fusion nail showed better results in terms of fusion, time to fusion and clinical outcome measured by Parker score and VAS but without statistical significance. The early revision rate was 10.4% and 20.8% presented a late complication requiring a surgery, due to nonunion or infection. 93.3% of infection was cured. Two patients live with a fistula (4.2%) and 1 was amputated (2.1%). CONCLUSION: Although burdened by a big complication rate, knee arthrodesis with an intramedullary nail provides satisfactory results and is a good alternative to above-knee-amputation. The Wichita® fusion nail shows a tendency to better results compared to the two other nails. LEVEL OF EVIDENCE: Case series, level IV.


Assuntos
Artroplastia do Joelho , Infecções Relacionadas à Prótese , Humanos , Estudos Retrospectivos , Pinos Ortopédicos/efeitos adversos , Artroplastia do Joelho/efeitos adversos , Joelho/cirurgia , Reoperação/métodos , Artrodese/efeitos adversos , Artrodese/métodos , Resultado do Tratamento , Infecções Relacionadas à Prótese/cirurgia , Infecções Relacionadas à Prótese/etiologia
2.
Rev Med Suisse ; 17(763): 2194-2200, 2021 Dec 15.
Artigo em Francês | MEDLINE | ID: mdl-34910406

RESUMO

Chronic osteomyelitis is an inflammatory process of the bone caused by an infectious agent. This condition leads to altered bone vascularization and thus to bone destruction and formation of necrotic bone fragments (sequestrum). The treatment of chronic osteomyelitis is primarily based on surgical management, which includes debridement of the sequestrum and sampling of bone tissue for microbiological analysis in order to initiate a targeted antibiotic therapy. A multidisciplinary approach is essential, involving expertise in orthopedic surgery, musculoskeletal imaging and nuclear medicine, infectious diseases, as well as plastic or vascular surgery for complex cases with soft tissue and/or vascular defects.


L'ostéomyélite chronique est un processus inflammatoire osseux causé par un agent infectieux. Cette pathologie provoque une altération de la vascularisation intraosseuse et périostée donnant lieu à des fragments d'os nécrotiques (séquestres). Le traitement de l'ostéomyélite chronique repose sur une prise en charge chirurgicale permettant de débrider les séquestres et de réaliser des prélèvements osseux pour des analyses microbiologiques afin d'instaurer une antibiothérapie ciblée sur l'agent pathogène. Une approche multidisciplinaire doit impliquer une expertise en chirurgie orthopédique, en imagerie musculosquelettique et médecine nucléaire, en maladies infectieuses, ainsi qu'en chirurgie plastique ou vasculaire pour les cas avec perte des tissus mous ou défaut de vascularisation.


Assuntos
Osteomielite , Adulto , Antibacterianos/uso terapêutico , Osso e Ossos , Doença Crônica , Desbridamento , Humanos , Osteomielite/tratamento farmacológico , Osteomielite/terapia
3.
BMC Infect Dis ; 20(1): 767, 2020 Oct 17.
Artigo em Inglês | MEDLINE | ID: mdl-33069221

RESUMO

BACKGROUND: Ureaplasma urealyticum is an intra-cellular bacterium frequently found colonizing the genital tract. Known complications include localized infections, which can result in premature deliveries. Septic arthritis due to U. urealyticum in healthy patients is exceptionally rare, although opportunistic septic arthritis in agammaglobulinemic patients have been reported. However, there are no reports of septic arthritis due to U. urealyticum following caesarean section or in the post-partum period. CASE PRESENTATION: A 38-year-old immunocompetent woman presented with severe right shoulder pain, 1 month following emergency caesarean section at 26 weeks of gestation for pre-eclampsia and spontaneous placental disruption with an uncomplicated post-operative recovery. Our suspicion of septic arthritis was confirmed with abundant pus following arthrotomy by a delto-pectoral approach. Awaiting culture results, empirical antibiotic treatment with intravenous amoxicilline and clavulanic acid was initiated. In spite of sterile cultures, clinical evolution was unfavorable with persistent pain, inflammation and purulent drainage, requiring two additional surgical débridement and lavage procedures. The 16S ribosomal RNA PCR of the purulent liquid was positive for U. urealyticum at 2.95 × 106 copies/ml, specific cultures inoculated a posteriori were positive for U. urealyticum. Levofloxacin and azithromycine antibiotherapy was initiated. Susceptibility testing showed an intermediate sensibility to ciprofloxacin and clarithromycin. The strain was susceptible to doxycycline. Following cessation of breastfeeding, we started antibiotic treatment with doxycycline for 4 weeks. The subsequent course was favorable with an excellent functional and biological outcome. CONCLUSIONS: We report the first case of septic arthritis due to U. urealyticum after caesarean section. We hypothesize that the breach of the genital mucosal barrier during the caesarean section led to hematogenous spread resulting in purulent septic arthritis. The initial beta-lactam based antibiotic treatment, initiated for a purulent arthritis, did not provide coverage for cell wall deficient organisms. Detection of 16S rRNA allowed for a correct microbiological diagnosis in a patient with an unexpected clinical course.


Assuntos
Artrite Infecciosa/microbiologia , Cesárea/efeitos adversos , Ombro/microbiologia , Infecções por Ureaplasma/diagnóstico , Ureaplasma urealyticum/genética , Adulto , Antibacterianos/uso terapêutico , Artrite Infecciosa/tratamento farmacológico , Doxiciclina/uso terapêutico , Feminino , Humanos , Testes de Sensibilidade Microbiana , Gravidez , Nascimento Prematuro , RNA Ribossômico 16S/genética , Resultado do Tratamento , Infecções por Ureaplasma/tratamento farmacológico , Infecções por Ureaplasma/microbiologia , Ureaplasma urealyticum/isolamento & purificação , Sistema Urogenital/microbiologia
4.
BMC Surg ; 20(1): 253, 2020 Oct 27.
Artigo em Inglês | MEDLINE | ID: mdl-33109131

RESUMO

BACKGROUND: Blunt abdominal traumas are often associated with intra-abdominal injuries and pelvic fractures. Traumatic abdominal wall hernias due to disruption of the abdominal wall muscles may be overlooked. Delayed diagnosis can lead to hernia related complications. CASE PRESENTATION: We present two cases of high kinetic trauma with pelvic fractures and acute traumatic abdominal wall herniation. Both of these cases suffered from a delayed diagnosis and needed surgery to treat the symptomatic herniation. CONCLUSION: Clinical reassessment and appropriate medical imaging are mandatory in patients with high kinetic abdominal blunt traumas and associated pelvic fracture, in order to prevent delayed diagnosis and possible complications.


Assuntos
Traumatismos Abdominais , Parede Abdominal , Fraturas Ósseas , Hérnia Abdominal , Ferimentos não Penetrantes , Traumatismos Abdominais/diagnóstico por imagem , Traumatismos Abdominais/etiologia , Parede Abdominal/diagnóstico por imagem , Parede Abdominal/cirurgia , Diagnóstico Tardio , Fraturas Ósseas/diagnóstico por imagem , Fraturas Ósseas/etiologia , Fraturas Cominutivas/diagnóstico por imagem , Fraturas Cominutivas/etiologia , Fraturas por Compressão/diagnóstico por imagem , Fraturas por Compressão/etiologia , Hérnia Abdominal/diagnóstico por imagem , Hérnia Abdominal/etiologia , Hérnia Abdominal/cirurgia , Herniorrafia , Humanos , Masculino , Pessoa de Meia-Idade , Traumatismo Múltiplo/diagnóstico , Ferimentos não Penetrantes/complicações , Ferimentos não Penetrantes/diagnóstico por imagem
5.
Int Orthop ; 44(10): 2131-2138, 2020 10.
Artigo em Inglês | MEDLINE | ID: mdl-32772320

RESUMO

PURPOSES: Acetabular fractures are more and more common in the elderly. Open reduction and internal fixation (ORIF) may lead to poor outcomes and high revision rates. Primary total hip arthroplasty (THA) combined with internal fixation, also known as the combined hip procedure (CHP), associated with dual mobility cup (DM-CHP) could be an efficient procedure in selected elderly patients. The aim of this study is to compare functional and radiological outcomes between ORIF and DM-CHP. METHODS: Between 2007 and 2018, 51 patients older than 65 years were surgically treated for acetabular fractures. Twenty-six patients were treated by DM-CHP and 25 by ORIF. Each group was divided into two subgroups regarding a single or combined approach. Hospital stay, surgical time, intraoperative blood loss, and complications were documented. The Harris Hip Score (HHS) was used for measuring the functional outcome. Radiological analysis was used to assess the centre of rotation in the DM-CHP group. RESULTS: Median surgery time and intra-operative blood loss were higher in DM-CHP than those in ORIF. Early medical complication rate was higher for a combined approach as compared with a single posterior approach in DM-CHP (p = 0.003). Dislocation rate was 7.7% in DM-CHP. Revision rate was higher in ORIF (20% versus 7.7%). HHS was similar in both groups. CONCLUSIONS: DM-CHP leads to similar functional outcomes and less revision than ORIF. This study strengthens the practice of using only the posterior approach for primary THA in the elderly. Dual mobility is a valid therapeutic option for acetabular fractures in elderly patients.


Assuntos
Artroplastia de Quadril , Fraturas do Quadril , Prótese de Quadril , Acetábulo/cirurgia , Idoso , Artroplastia de Quadril/efeitos adversos , Fixação Interna de Fraturas/efeitos adversos , Fraturas do Quadril/diagnóstico por imagem , Fraturas do Quadril/epidemiologia , Fraturas do Quadril/cirurgia , Humanos , Reoperação , Estudos Retrospectivos
6.
Arch Orthop Trauma Surg ; 140(8): 1013-1027, 2020 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-31659475

RESUMO

Fracture-related infection (FRI) remains a challenging complication that creates a heavy burden for orthopaedic trauma patients, their families and treating physicians, as well as for healthcare systems. Standardization of the diagnosis of FRI has been poor, which made the undertaking and comparison of studies difficult. Recently, a consensus definition based on diagnostic criteria for FRI was published. As a well-established diagnosis is the first step in the treatment process of FRI, such a definition should not only improve the quality of published reports but also daily clinical practice. The FRI consensus group recently developed guidelines to standardize treatment pathways and outcome measures. At the center of these recommendations was the implementation of a multidisciplinary team (MDT) approach. If such a team is not available, it is recommended to refer complex cases to specialized centers where a MDT is available and physicians are experienced with the treatment of FRI. This should lead to appropriate use of antimicrobials and standardization of surgical strategies. Furthermore, an MDT could play an important role in host optimization. Overall two main surgical concepts are considered, based on the fact that fracture fixation devices primarily target fracture consolidation and can be removed after healing, in contrast to periprosthetic joint infection were the implant is permanent. The first concept consists of implant retention and the second consists of implant removal (healed fracture) or implant exchange (unhealed fracture). In both cases, deep tissue sampling for microbiological examination is mandatory. Key aspects of the surgical management of FRI are a thorough debridement, irrigation with normal saline, fracture stability, dead space management and adequate soft tissue coverage. The use of local antimicrobials needs to be strongly considered. In case of FRI, empiric broad-spectrum antibiotic therapy should be started after tissue sampling. Thereafter, this needs to be adapted according to culture results as soon as possible. Finally, a minimum follow-up of 12 months after cessation of therapy is recommended. Standardized patient outcome measures purely focusing on FRI are currently not available but the patient-reported outcomes measurement information system (PROMIS) seems to be the preferred tool to assess the patients' short and long-term outcome. This review summarizes the current general principles which should be considered during the whole treatment process of patients with FRI based on recommendations from the FRI Consensus Group.Level of evidence: Level V.


Assuntos
Infecções Bacterianas , Fraturas Ósseas , Infecção da Ferida Cirúrgica , Antibacterianos/uso terapêutico , Consenso , Fixação Interna de Fraturas/efeitos adversos , Fraturas Ósseas/complicações , Fraturas Ósseas/cirurgia , Humanos , Guias de Prática Clínica como Assunto
7.
Eur J Orthop Surg Traumatol ; 30(5): 877-884, 2020 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-32140838

RESUMO

INTRODUCTION: Surgical stabilization of posterior pelvic ring fractures can be achieved by closed reduction and percutaneous fixation (CRPF) or by open reduction and internal fixation (ORIF). The aim of the present study is to compare the clinical results of both methods. MATERIAL AND METHODS: Medical records of 36 patients consecutively operated for unstable pelvic ring injuries were retrospectively reviewed. We compared 22 patients treated with CRPF versus 14 patients stabilized by using ORIF between 2007 and 2017. The Majeed and Pohlemann scores were used to evaluate postoperative functional outcomes. Complications like blood loss, infection rate, Neurological injury, the operative time and the length of hospital stay were analyzed. RESULTS: The median Majeed pelvic score was 87 points for the CRPF technique compared with 69 points for the ORIF technique. The median Pohlemann score, operative time and length of hospitalization were similar between the two groups. The median blood loss for the CRPF technique was 300 ml compared to 500 ml for the ORIF technique. CRPF and ORIF procedure had each one neurological lesion. There was one case of infection in the ORIF group and none in the CRPF group. No measurements except for the blood loss have reached the significance threshold. CONCLUSION: The CRPF technique shows a clear decrease in blood loss. There was no statistically significant difference in the functional results, infection rate, neurological injury, operative time and hospital stay between both techniques.


Assuntos
Redução Fechada , Fixação Interna de Fraturas/métodos , Fraturas Ósseas/cirurgia , Redução Aberta , Ossos Pélvicos/lesões , Adulto , Perda Sanguínea Cirúrgica , Parafusos Ósseos , Redução Fechada/efeitos adversos , Feminino , Fixação Interna de Fraturas/efeitos adversos , Fixação Interna de Fraturas/instrumentação , Fraturas Ósseas/diagnóstico por imagem , Humanos , Infecções/etiologia , Tempo de Internação , Masculino , Pessoa de Meia-Idade , Redução Aberta/efeitos adversos , Duração da Cirurgia , Ossos Pélvicos/diagnóstico por imagem , Traumatismos dos Nervos Periféricos/etiologia , Estudos Retrospectivos
8.
Eur J Nucl Med Mol Imaging ; 46(4): 957-970, 2019 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-30675635

RESUMO

INTRODUCTION: In adults with a suspicion of peripheral bone infection, evidence-based guidelines in choosing the most accurate diagnostic strategy are lacking. AIM AND METHODS: To provide an evidence-based, multidisciplinary consensus document on the diagnostic management of adult patients with PBIs, we performed a systematic review of relevant infectious, microbiological, orthopedic, radiological, and nuclear medicine literature. Delegates from four European societies (European Bone and Joint Infection Society, European Society of Microbiology and Infectious Diseases, European Society or Radiology, and European Association of Nuclear Medicine) defined clinical questions to be addressed, thoroughly reviewed the literature pertinent to each of the questions, and thereby evaluated the diagnostic accuracy of each diagnostic technique. Inclusion of the papers per statement was based on a PICO (Population/problem - Intervention/indicator - Comparator - Outcome) question following the strategy reported by the Oxford Centre for Evidence-based Medicine. For each statement, the level of evidence was graded according to the 2011 review of the Oxford Centre for Evidence-based Medicine. All approved statements were addressed taking into consideration the available diagnostic procedures, patient acceptance, tolerability, complications, and costs in Europe. Finally, a commonly agreed-upon diagnostic flowchart was developed.


Assuntos
Consenso , Documentação , Medicina Nuclear , Osteíte/diagnóstico por imagem , Osteomielite/diagnóstico por imagem , Sociedades Científicas , Adulto , Antibacterianos/uso terapêutico , Europa (Continente) , Medicina Baseada em Evidências , Humanos , Osteíte/tratamento farmacológico , Osteomielite/tratamento farmacológico
9.
Eur J Nucl Med Mol Imaging ; 46(4): 971-988, 2019 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-30683987

RESUMO

BACKGROUND: For the diagnosis of prosthetic joint infection, real evidence-based guidelines to aid clinicians in choosing the most accurate diagnostic strategy are lacking. AIM AND METHODS: To address this need, we performed a multidisciplinary systematic review of relevant nuclear medicine, radiological, orthopaedic, infectious, and microbiological literature to define the diagnostic accuracy of each diagnostic technique and to address and provide evidence-based answers on uniform statements for each topic that was found to be important to develop a commonly agreed upon diagnostic flowchart. RESULTS AND CONCLUSION: The approach used to prepare this set of multidisciplinary guidelines was to define statements of interest and follow the procedure indicated by the Oxford Centre for Evidence-based Medicine (OCEBM).


Assuntos
Consenso , Documentação , Medicina Nuclear , Infecções Relacionadas à Prótese/diagnóstico , Sociedades Científicas , Europa (Continente) , Medicina Baseada em Evidências , Humanos , Infecções Relacionadas à Prótese/diagnóstico por imagem
10.
Eur J Nucl Med Mol Imaging ; 46(5): 1203, 2019 May.
Artigo em Inglês | MEDLINE | ID: mdl-30737519

RESUMO

The authors regret to inform the readers that one of the author's name in the original publication of this article was spelled incorrectly as Victor Casar-Pullicino. The correct spelling is Victor N. Cassar-Pullicino and is now presented correctly in this article.

11.
Eur Radiol ; 29(12): 6425-6438, 2019 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-31250170

RESUMO

OBJECTIVES: Peripheral bone infection (PBI) and prosthetic joint infection (PJI) are two different infectious conditions of the musculoskeletal system. They have in common to be quite challenging to be diagnosed and no clear diagnostic flowchart has been established. Thus, a conjoined initiative on these two topics has been initiated by the European Society of Radiology (ESR), the European Association of Nuclear Medicine (EANM), the European Bone and Joint Infection Society (EBJIS), and the European Society of Clinical Microbiology and Infectious Diseases (ESCMID). The purpose of this work is to provide an overview on the two consensus documents on PBI and PJI that originated by the conjoined work of the ESR, EANM, and EBJIS (with ESCMID endorsement). METHODS AND RESULTS: After literature search, a list of 18 statements for PBI and 25 statements for PJI were drafted in consensus on the most debated diagnostic challenges on these two topics, with emphasis on imaging. CONCLUSIONS: Overall, white blood cell scintigraphy and magnetic resonance imaging have individually demonstrated the highest diagnostic performance over other imaging modalities for the diagnosis of PBI and PJI. However, the choice of which advanced diagnostic modality to use first depends on several factors, such as the benefit for the patient, local experience of imaging specialists, costs, and availability. Since robust, comparative studies among most tests do not exist, the proposed flowcharts are based not only on existing literature but also on the opinion of multiple experts involved on these topics. KEY POINTS: • For peripheral bone infection and prosthetic joint infection, white blood cell and magnetic resonance imaging have individually demonstrated the highest diagnostic performance over other imaging modalities. • Two evidence- and expert-based diagnostic flowcharts involving variable combination of laboratory tests, biopsy methods, and radiological and nuclear medicine imaging modalities are proposed by a multi-society expert panel. • Clinical application of these flowcharts depends on several factors, such as the benefit for the patient, local experience, costs, and availability.


Assuntos
Doenças Ósseas Infecciosas/diagnóstico por imagem , Imageamento por Ressonância Magnética/métodos , Infecções Relacionadas à Prótese/diagnóstico por imagem , Consenso , Europa (Continente) , Humanos , Cintilografia , Sociedades Médicas
12.
BMC Geriatr ; 19(1): 180, 2019 07 01.
Artigo em Inglês | MEDLINE | ID: mdl-31262265

RESUMO

BACKGROUND: Hip fracture causes moderate to severe pain and while fascia iliaca block has been reported to provide analgesic benefit, most previous trials were unblinded, with subsequent high risks of performance, selection and detection biases. In this randomized, control double-blind trial, we tested the hypothesis that a fascia iliaca block provides effective analgesia for patients suffering from hip fracture. METHODS: Thirty ASA I-III hip fracture patients over 70 years old, who received prehospital morphine, were randomized to receive either a fascia iliaca block using 30 ml of bupivacaine 0.5% with epinephrine 1:200,000 or a sham injection with normal saline. The fascia iliaca block was administered by emergency medicine physicians trained to perform an anatomic landmark-based technique. The primary outcome was the comparison between groups of the longitudinal pain score profiles at rest over the first 45 min following the procedure (numeric rating scale, 0-10). Secondary outcomes included the longitudinal pain score profiles on movement and the comparison over 4 h, 8 h, 12 h, and 24 h after the procedure, along with cumulative intravenous morphine consumption at 24 h. RESULTS: At baseline, the fascia iliaca group had a lower mean pain score than the sham injection group, both at rest (difference = - 0.9, 95%CI [- 2.4, 0.5]) and on movement (difference = - 0.9, 95%CI [- 2.7; 0.9]). These differences remained 45 min after the procedure and the two longitudinal pain score profiles were parallel both for patients at rest and on movement (test of parallelism for patients at rest p = 0.53 and on movement p = 0.45). The same parallel change in pain scores over time was observed over 24 h of follow-up (test of parallelism for patients at rest p = 0.82 and on movement p = 0.12). These results were confirmed after adjustment for gender, ASA score, and cumulative sums of intravenous morphine received pre-procedure and during-follow-up. In addition, there was no difference between the two groups in total cumulative intravenous morphine consumption at 24 h. CONCLUSION: Fascia iliaca block following anatomic landmarks may not provide supplementary analgesia for patients suffering from hip fracture, when low pain scores are reported after prehospital morphine. Additional larger trials will help reach definitive conclusion. TRIAL REGISTRATION NUMBER: Clinicaltrials.gov - NCT02433548 . The study was registered retrospectively.


Assuntos
Bloqueio Nervoso Autônomo/métodos , Serviço Hospitalar de Emergência , Fraturas do Quadril/diagnóstico , Fraturas do Quadril/tratamento farmacológico , Manejo da Dor/métodos , Medição da Dor/métodos , Idoso , Idoso de 80 Anos ou mais , Analgesia/métodos , Método Duplo-Cego , Feminino , Humanos , Estudos Longitudinais , Masculino , Medição da Dor/efeitos dos fármacos , Estudos Retrospectivos
13.
Rev Med Suisse ; 14(631): 2243-2247, 2018 Dec 12.
Artigo em Francês | MEDLINE | ID: mdl-30550019

RESUMO

So-called metal allergy is a new interesting subject in orthopedics. Two different ways of thinking prevail in the literature. In the German orthopaedic literature, the diagnosis of metal allergy is often described and considered a real pathology, while we can find a more skeptical approach to this entity in Anglo-Saxons literature. Being an exclusion diagnostic, without any universal consensus on how to diagnose or on the treatment, the aim of this article is to clarify what we know about metal allergy today.


La notion d'allergie aux métaux, en réalité une hypersensibilité retardée (type IV), est un sujet émergent dans la littérature orthopédique. Nos collègues allemands s'y intéressent particulièrement, contrairement aux Anglais qui restent plus réservés. Restant un diagnostic d'exclusion, sans aucune ligne de conduite universelle, tant sur le plan diagnostique que thérapeutique, il nous paraît essentiel de faire le point sur cette entité.


Assuntos
Hipersensibilidade , Metais , Ortopedia , Humanos , Metais/efeitos adversos
14.
Rev Med Suisse ; 14(631): 2264-2267, 2018 Dec 12.
Artigo em Francês | MEDLINE | ID: mdl-30550023

RESUMO

Olecranon fractures represent 5 % of all adult fractures. Management is most often surgical. Conservative treatment is recommended for non-displaced fractures or patients who would be poor surgical candidates. Prolonged immobilization of the elbow may cause joint stiffness, whereas surgical treatment can be complicated by loss of reduction or wound issues with secondary infection of the material. In this article, we discuss the pathology and the principles of treatment based on the literature, to allow the general practitioner to guide the patient towards the most suitable treatment.


Les fractures de l'olécrâne représentent 5 % de l'ensemble des fractures. Leur prise en charge est le plus souvent chirurgicale et le traitement conservateur est réservé aux fractures non déplacées ou à des patients qui seraient de mauvais candidats à la chirurgie. L'immobilisation prolongée du coude peut être responsable d'une raideur articulaire, alors qu'un traitement chirurgical peut entraîner des complications comme le démontage de l'ostéosynthèse ou des problèmes de cicatrisation avec infection précoce du matériel. Dans cet article, nous voulons rappeler les connaissances anatomopathologiques ainsi que les principes du traitement, basés sur la littérature, afin de permettre au médecin d'orienter son patient vers le traitement le plus adapté.


Assuntos
Articulação do Cotovelo , Olécrano , Fraturas da Ulna , Adulto , Articulação do Cotovelo/cirurgia , Fixação Interna de Fraturas , Humanos , Olécrano/lesões , Resultado do Tratamento , Fraturas da Ulna/cirurgia
15.
Adv Exp Med Biol ; 971: 101-111, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-27757937

RESUMO

Total Joint Arthroplasty (TJA) continues to gain acceptance as the standard of care for the treatment of severe degenerative joint disease, and is considered one of the most successful surgical interventions in the history of medicine. A devastating complication after TJA is infection. Periprosthetic joint infection (PJI), represents one of the major causes of failure and remains a significant challenge facing orthopaedics today. PJI usually requires additional surgery including revision of the implants, fusion or amputations causing tremendous patient suffering but also a heavy health economics burden. PJI is at the origin of around 20-25 % of total knee arthroplasty (Bozic et al. 2010; de Gorter et al. 2015; Sundberg et al. 2015) and 12-15 % of total hip arthroplasty (Bozic et al. 2009; Garellick et al. 2014; de Gorter et al. 2015) failures.


Assuntos
Artrocentese/efeitos adversos , Artropatias/diagnóstico , Procedimentos Ortopédicos/efeitos adversos , Infecções Relacionadas à Prótese/diagnóstico , Algoritmos , Humanos , Artropatias/etiologia , Artropatias/microbiologia
16.
BMC Surg ; 17(1): 104, 2017 Nov 09.
Artigo em Inglês | MEDLINE | ID: mdl-29121893

RESUMO

BACKGROUND: Pelvic fractures are severe injuries with frequently associated multi-system trauma and a high mortality rate. The value of the pelvic fracture pattern for predicting transfusion requirements and mortality is not entirely clear. To address hemorrhage from pelvic injuries, the early application of pelvic binders is now recommended and arterial angio-embolization is widely used for controlling arterial bleeding. Our aim was to assess the association of the pelvic fracture pattern according to the Tile classification system with transfusion requirements and mortality rates, and to evaluate the correlation between the use of pelvic binders and arterial angio-embolization and the mortality of patients with pelvic fractures. METHODS: Single-center retrospective cohort study including all consecutive patients with a pelvic fracture from January 2008 to June 2015. All radiological fracture patterns were independently reviewed and grouped according to the Tile classification system. Data on patient demographics, use of pelvic binders and arterial angio-embolization, transfusion requirements and mortality were extracted from the institutional trauma registry and analyzed. RESULTS: The present study included 228 patients. Median patient age was 43.5 years and 68.9% were male. The two independent observers identified 105 Tile C (46.1%), 71 Tile B (31.1%) and 52 Tile A (22.8%) fractures, with substantial to almost perfect interobserver agreement (Kappa 0.70-0.83). Tile C fractures were associated with a higher mortality rate (p = 0.001) and higher transfusion requirements (p < 0.0001) than Tile A or B fractures. Arterial angio-embolization for pelvic bleeding (p = 0.05) and prehospital pelvic binder placement (p = 0.5) were not associated with differences in mortality rates. CONCLUSIONS: Tile C pelvic fractures are associated with higher transfusion requirements and a higher mortality rate than Tile A or B fractures. No association between the use of pelvic binders or arterial angio-embolization and survival was observed in this cohort of patients with pelvic fractures.


Assuntos
Transfusão de Sangue , Embolização Terapêutica , Fraturas Ósseas/epidemiologia , Ossos Pélvicos/lesões , Adulto , Feminino , Hemorragia/epidemiologia , Humanos , Masculino , Pessoa de Meia-Idade , Pelve , Estudos Retrospectivos
17.
BMC Musculoskelet Disord ; 17: 156, 2016 Apr 12.
Artigo em Inglês | MEDLINE | ID: mdl-27067804

RESUMO

BACKGROUND: Granulicatella and Abiotrophia spp. are difficult to detect due to their complex nutritional requirements. Infections with these organisms are associated with high treatment failure rates. We report the first implant-associated infection caused by Granulicatella para-adiacens, which was cured with anti-microbial treatment consisting of anti-biofilm-active rifampin and debridement, exchange of mobile parts and retention of the prosthesis. CASE PRESENTATION: Patient with a history of left hip arthroplasty presented with acute onset of fever, pain and limited range of motion of the left hip. Arthrocentesis of the affected joint yielded purulent fluid and exchange of mobile parts of the prosthesis, but retention of fixed components was performed. Granulicatella para-adiacens grew from preoperative and intraoperative cultures, including sonication fluid of the removed implant. The transesophageal echocardiography showed a vegetation on the mitral valve; the orthopantogram demonstrated a periapical dental abscess. The patient was treated with intravenous penicillin G and gentamicin for 4 weeks, followed by levofloxacin and rifampin for additional 2 months. At discharge and at follow-up 1, 2 and 5 years later, the patient was noted to have a functional, pain-free, and radiologically stable hip prosthesis and the serum C-reactive protein was normal. CONCLUSIONS: Although considered a difficult-to-treat organism, we report a successful treatment of the Granulicatella hip prosthesis infection with prosthesis retention and a prolonged antibiofilm therapy including rifampin. The periapical dental abscess is considered the primary focus of hematogenously infected hip prosthesis, underlining the importance treatment of periodontitis prior to arthroplasty and of proper oral hygiene for prevention of hematogenous infection after arthroplasty.


Assuntos
Artroplastia de Quadril/efeitos adversos , Infecções por Bactérias Gram-Positivas/diagnóstico por imagem , Infecções por Bactérias Gram-Positivas/terapia , Retenção da Prótese , Infecções Relacionadas à Prótese/diagnóstico por imagem , Infecções Relacionadas à Prótese/terapia , Abiotrophia , Idoso , Antibacterianos/uso terapêutico , Desbridamento/métodos , Humanos , Masculino , Retenção da Prótese/métodos , Resultado do Tratamento
18.
Eur J Orthop Surg Traumatol ; 26(4): 429-34, 2016 May.
Artigo em Inglês | MEDLINE | ID: mdl-27017334

RESUMO

BACKGROUND: With improved diagnostic methods and longer prosthesis indwelling time, the frequency of diagnosed Propionibacterium prosthetic joint infections (PJI) is increasing. Data on clinical, microbiological, radiological and surgical treatment are limited, and importance of this organism in PJI is probably underestimated. MATERIALS AND METHODS: We retrospectively analyzed patients with PJI caused by Propionibacterium spp. diagnosed at our institution between 2000 and 2012. Patient data were retrieved through chart review, and the outcome was evaluated at patient follow-up visits. RESULTS: Of 15 included patients (median age 65 years, range 44-87), 8 hip, 4 shoulder, 2 knee and 1 ankle PJI were recorded. The median time from implantation to diagnosis of PJI was 44.2 months (range 2-180 months). Most PJI (8 patients, 53 %) were diagnosed late (>24 months after arthroplasty). Persistent pain was present in 13, local joint symptoms in 8, fever in 4 and sinus tract in 3 patients. Radiological signs of loosening were present in 11 patients (73 %). Organisms were detected in intraoperative biopsy (n = 5), sonication (n = 4) or preoperative joint puncture (n = 4). In three cases coinfection with a coagulase-negative staphylococcus was diagnosed. Revision surgery was performed in all cases. After a mean follow-up of 16 months after revision surgery (range 4-37 months), 14 patients (93 %) showed no signs or symptoms of infection and had a functional prosthesis; one patient experienced a new infection with another organism (Staphylococcus epidermidis). CONCLUSION: Patients with persistent postoperative pain and/or loosening of implants should be screened for PJI with low-virulent organisms such as Propionibacterium, including.


Assuntos
Artroplastia de Substituição/efeitos adversos , Infecções por Bactérias Gram-Positivas/cirurgia , Prótese Articular/efeitos adversos , Propionibacterium acnes , Infecções Relacionadas à Prótese/cirurgia , Adulto , Idoso , Feminino , Infecções por Bactérias Gram-Positivas/diagnóstico , Humanos , Masculino , Pessoa de Meia-Idade , Reoperação , Estudos Retrospectivos
19.
Rev Med Suisse ; 12(543): 2164-2167, 2016 Dec 14.
Artigo em Francês | MEDLINE | ID: mdl-28707831

RESUMO

Total joint replacement comes with a high success rate and has been shown to have a very positive impact on our patients suffering from arthritis. Against all efforts about 2 % of our patients will suffer an implant related infection. As the treatment of infected arthroplasties is difficult and expensive the knowledge of risk factors is becoming more and more important for the treatment team in order to improve our preventive measures. Prevention must be performed pre-, intra- and postoperatively. Preoperative optimization of blood sugar levels, nutritional status and correction of general anaemia for example are paramount and the general practitioner as well as the surgeon should be aware of these and other modifiable risk factors in order to operate on the patient in the best possible conditions.


La chirurgie prothétique est une chirurgie dont l'impact est extrêmement favorable pour nos patients souffrant d'une arthrose. Malgré des progrès considérables pour diminuer le taux d'infections postopératoires, cette complication grave survient dans encore environ 2 % des cas. La prévention joue un rôle très important pour diminuer l'incidence de ces infections, à la fois en pré, péri et postopératoire. Le chirurgien et le médecin traitant doivent connaître, rechercher et prendre en charge les facteurs de risque connus d'infection avant toute chirurgie orthopédique. Les principaux facteurs de risque souvent modifiables comme les hyperglycémies, les anémies et la dénutrition seront discutés dans cet article.


Assuntos
Artroplastia de Substituição/métodos , Clínicos Gerais/organização & administração , Infecções Relacionadas à Prótese/prevenção & controle , Anemia/terapia , Artroplastia de Substituição/efeitos adversos , Humanos , Procedimentos Ortopédicos/efeitos adversos , Procedimentos Ortopédicos/métodos , Papel do Médico , Infecções Relacionadas à Prótese/etiologia , Fatores de Risco
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