Detalhe da pesquisa
1.
Vpx requires active cellular dNTP biosynthesis to effectively counteract the anti-lentivirus activity of SAMHD1 in macrophages.
J Biol Chem
; 299(8): 104984, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37390988
2.
Biochemical functions and structure of Caenorhabditis elegans ZK177.8 protein: Aicardi-Goutières syndrome SAMHD1 dNTPase ortholog.
J Biol Chem
; 299(9): 105148, 2023 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-37567474
3.
Structural and functional characterization explains loss of dNTPase activity of the cancer-specific R366C/H mutant SAMHD1 proteins.
J Biol Chem
; 297(4): 101170, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34492268
4.
ATR kinase supports normal proliferation in the early S phase by preventing replication resource exhaustion.
Nat Commun
; 14(1): 3618, 2023 06 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37336885
5.
ATR kinase supports normal proliferation in the early S phase by preventing replication resource exhaustion.
bioRxiv
; 2023 May 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-37292881
6.
Mechanistic Interplay between HIV-1 Reverse Transcriptase Enzyme Kinetics and Host SAMHD1 Protein: Viral Myeloid-Cell Tropism and Genomic Mutagenesis.
Viruses
; 14(8)2022 07 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-35893688
7.
SAMHD1 deacetylation by SIRT1 promotes DNA end resection by facilitating DNA binding at double-strand breaks.
Nat Commun
; 13(1): 6707, 2022 11 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36344525
8.
In silico screening identifies a novel small molecule inhibitor that counteracts PARP inhibitor resistance in ovarian cancer.
Sci Rep
; 11(1): 8042, 2021 04 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-33850183
9.
Disproportionate presence of adenosine in mitochondrial and chloroplast DNA of Chlamydomonas reinhardtii.
iScience
; 24(1): 102005, 2021 Jan 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-33490913
10.
Ribonucleotide incorporation in yeast genomic DNA shows preference for cytosine and guanosine preceded by deoxyadenosine.
Nat Commun
; 11(1): 2447, 2020 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32415081