Detalhe da pesquisa
1.
STING mediates neurodegeneration and neuroinflammation in nigrostriatal α-synucleinopathy.
Proc Natl Acad Sci U S A
; 119(15): e2118819119, 2022 04 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35394877
2.
Complement and Coagulation Cascades are Potentially Involved in Dopaminergic Neurodegeneration in α-Synuclein-Based Mouse Models of Parkinson's Disease.
J Proteome Res
; 20(7): 3428-3443, 2021 07 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34061533
3.
Parkin interacting substrate zinc finger protein 746 is a pathological mediator in Parkinson's disease.
Brain
; 142(8): 2380-2401, 2019 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31237944
4.
TRPV1 on astrocytes rescues nigral dopamine neurons in Parkinson's disease via CNTF.
Brain
; 138(Pt 12): 3610-22, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26490328
5.
Aplp1 interacts with Lag3 to facilitate transmission of pathologic α-synuclein.
Nat Commun
; 15(1): 4663, 2024 May 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-38821932
6.
The c-Abl inhibitor IkT-148009 suppresses neurodegeneration in mouse models of heritable and sporadic Parkinson's disease.
Sci Transl Med
; 15(679): eabp9352, 2023 01 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-36652533
7.
Enhanced mTORC1 signaling and protein synthesis in pathologic α-synuclein cellular and animal models of Parkinson's disease.
Sci Transl Med
; 15(724): eadd0499, 2023 11 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38019930
8.
Gender-specific expression of beta1 integrin of VLA-4 in myelin basic protein-primed T cells: implications for gender bias in multiple sclerosis.
J Immunol
; 184(11): 6103-13, 2010 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20483780
9.
Myelin basic protein priming reduces the expression of Foxp3 in T cells via nitric oxide.
J Immunol
; 184(4): 1799-809, 2010 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20083653
10.
Neuronal NLRP3 is a parkin substrate that drives neurodegeneration in Parkinson's disease.
Neuron
; 110(15): 2422-2437.e9, 2022 08 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35654037
11.
Suppression of regulatory T cells by IL-12p40 homodimer via nitric oxide.
J Immunol
; 183(3): 2045-58, 2009 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19587012
12.
Sodium benzoate, a metabolite of cinnamon and a food additive, reduces microglial and astroglial inflammatory responses.
J Immunol
; 183(9): 5917-27, 2009 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19812204
13.
Lymphocyte Activation Gene 3 (Lag3) Contributes to α-Synucleinopathy in α-Synuclein Transgenic Mice.
Front Cell Neurosci
; 15: 656426, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33776654
14.
Simvastatin inhibits the activation of p21ras and prevents the loss of dopaminergic neurons in a mouse model of Parkinson's disease.
J Neurosci
; 29(43): 13543-56, 2009 Oct 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-19864567
15.
Defects in Mitochondrial Biogenesis Drive Mitochondrial Alterations in PARKIN-Deficient Human Dopamine Neurons.
Stem Cell Reports
; 15(3): 629-645, 2020 09 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32795422
16.
Inhibition of calpain attenuates encephalitogenicity of MBP-specific T cells.
J Neurochem
; 110(6): 1895-907, 2009 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-19627443
17.
Poly(ADP-ribose) drives pathologic α-synuclein neurodegeneration in Parkinson's disease.
Science
; 362(6414)2018 11 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30385548
18.
Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson's disease.
Nat Med
; 24(7): 931-938, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29892066
19.
Induction of glial fibrillary acidic protein expression in astrocytes by nitric oxide.
J Neurosci
; 26(18): 4930-9, 2006 May 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-16672668
20.
c-Abl and Parkinson's Disease: Mechanisms and Therapeutic Potential.
J Parkinsons Dis
; 7(4): 589-601, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-29103051