Pesquisa | Portal de Pesquisa da BVS

1.

Hypophosphorylated pRb knock-in mice exhibit hallmarks of aging and vitamin C-preventable diabetes.

Jiang, Zhe; Li, Huiqin; Schroer, Stephanie A; Voisin, Veronique; Ju, YoungJun; Pacal, Marek; Erdmann, Natalie; Shi, Wei; Chung, Philip E D; Deng, Tao; Chen, Nien-Jung; Ciavarra, Giovanni; Datti, Alessandro; Mak, Tak W; Harrington, Lea; Dick, Frederick A; Bader, Gary D; Bremner, Rod; Woo, Minna; Zacksenhaus, Eldad.

EMBO J ; 41(4): e106825, 2022 02 15.

Artigo em Inglês | MEDLINE | ID: mdl-35023164

2.

Progenitor division and cell autonomous neurosecretion are required for rod photoreceptor sublaminar positioning.

Gurdita, Akshay; Pham Truong, Victor Q B; Dolati, Parnian; Juric, Matey; Tachibana, Nobuhiko; Liu, Zhongda C; Ortín-Martínez, Arturo; Ibrahimi, Mostafa; Pokrajac, Nenad T; Comanita, Lacrimioara; Pacal, Marek; Huang, Mengjia; Sugita, Shuzo; Bremner, Rod; Wallace, Valerie A.

Proc Natl Acad Sci U S A ; 120(42): e2308204120, 2023 10 17.

Artigo em Inglês | MEDLINE | ID: mdl-37812728

3.

Photoreceptor nanotubes mediate the in vivo exchange of intracellular material.

Ortin-Martinez, Arturo; Yan, Nicole E; Tsai, En Leh Samuel; Comanita, Lacrimioara; Gurdita, Akshay; Tachibana, Nobuhiko; Liu, Zhongda C; Lu, Suying; Dolati, Parnian; Pokrajac, Neno T; El-Sehemy, Ahmed; Nickerson, Philip E B; Schuurmans, Carol; Bremner, Rod; Wallace, Valerie A.

EMBO J ; 40(22): e107264, 2021 11 15.

Artigo em Inglês | MEDLINE | ID: mdl-34494680

4.

Retinoblastoma, an inside job.

Bremner, Rod.

Cell ; 137(6): 992-4, 2009 Jun 12.

Artigo em Inglês | MEDLINE | ID: mdl-19524501

5.

Pou2f1 and Pou2f2 cooperate to control the timing of cone photoreceptor production in the developing mouse retina.

Javed, Awais; Mattar, Pierre; Lu, Suying; Kruczek, Kamil; Kloc, Magdalena; Gonzalez-Cordero, Anai; Bremner, Rod; Ali, Robin R; Cayouette, Michel.

Development ; 147(18)2020 09 28.

Artigo em Inglês | MEDLINE | ID: mdl-32878923

6.

Extracellular phosphorylation drives the formation of neuronal circuitry.

Harada, Hidekiyo; Farhani, Nahal; Wang, Xue-Fan; Sugita, Shuzo; Charish, Jason; Attisano, Liliana; Moran, Michael; Cloutier, Jean-Francois; Reber, Michael; Bremner, Rod; Monnier, Philippe P.

Nat Chem Biol ; 15(11): 1035-1042, 2019 11.

Artigo em Inglês | MEDLINE | ID: mdl-31451763

7.

Comparison of SARS-CoV-2 indirect and direct RT-qPCR detection methods.

Pearson, Joel D; Trcka, Daniel; Lu, Suying; Hyduk, Sharon J; Jen, Mark; Aynaud, Marie-Ming; Hernández, J Javier; Peidis, Philippos; Barrios-Rodiles, Miriam; Chan, Kin; Woodgett, Jim; Mazzulli, Tony; Attisano, Liliana; Pelletier, Laurence; Cybulsky, Myron I; Wrana, Jeffrey L; Bremner, Rod.

Virol J ; 18(1): 99, 2021 05 17.

Artigo em Inglês | MEDLINE | ID: mdl-34001180

8.

The chromatin-remodeling enzyme BRG1 coordinates CIITA induction through many interdependent distal enhancers.

Ni, Zuyao; Abou El Hassan, Mohamed; Xu, Zhaodong; Yu, Tao; Bremner, Rod.

Nat Immunol ; 9(7): 785-93, 2008 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-18500344

9.

Frequent interferon regulatory factor 1 (IRF1) binding at remote elements without histone modification.

Abou El Hassan, Mohamed; Huang, Katherine; Xu, Zhaodong; Yu, Tao; Bremner, Rod.

J Biol Chem ; 293(26): 10353-10362, 2018 06 29.

Artigo em Inglês | MEDLINE | ID: mdl-29748386

10.

Properties of STAT1 and IRF1 enhancers and the influence of SNPs.

Abou El Hassan, Mohamed; Huang, Katherine; Eswara, Manoja B K; Xu, Zhaodong; Yu, Tao; Aubry, Arthur; Ni, Zuyao; Livne-Bar, Izzy; Sangwan, Monika; Ahmad, Mohamad; Bremner, Rod.

BMC Mol Biol ; 18(1): 6, 2017 03 09.

Artigo em Inglês | MEDLINE | ID: mdl-28274199

11.

Identification of the SLAM Adapter Molecule EAT-2 as a Lupus-Susceptibility Gene That Acts through Impaired Negative Regulation of Dendritic Cell Signaling.

Talaei, Nafiseh; Yu, Tao; Manion, Kieran; Bremner, Rod; Wither, Joan E.

J Immunol ; 195(10): 4623-31, 2015 Nov 15.

Artigo em Inglês | MEDLINE | ID: mdl-26432891

12.

Polycomb Repressive Complex 2 Confers BRG1 Dependency on the CIITA Locus.

Abou El Hassan, Mohamed; Yu, Tao; Song, Lan; Bremner, Rod.

J Immunol ; 194(10): 5007-13, 2015 May 15.

Artigo em Inglês | MEDLINE | ID: mdl-25862816

13.

Retinal degeneration depends on Bmi1 function and reactivation of cell cycle proteins.

Zencak, Dusan; Schouwey, Karine; Chen, Danian; Ekström, Per; Tanger, Ellen; Bremner, Rod; van Lohuizen, Maarten; Arsenijevic, Yvan.

Proc Natl Acad Sci U S A ; 110(7): E593-601, 2013 Feb 12.

Artigo em Inglês | MEDLINE | ID: mdl-23359713

14.

Cancer: The origin of human retinoblastoma.

Bremner, Rod; Sage, Julien.

Nature ; 514(7522): 312-3, 2014 Oct 16.

Artigo em Inglês | MEDLINE | ID: mdl-25252972

15.

Division and apoptosis of E2f-deficient retinal progenitors.

Chen, Danian; Pacal, Marek; Wenzel, Pamela; Knoepfler, Paul S; Leone, Gustavo; Bremner, Rod.

Nature ; 462(7275): 925-9, 2009 Dec 17.

Artigo em Inglês | MEDLINE | ID: mdl-20016601

16.

E2f1-3 switch from activators in progenitor cells to repressors in differentiating cells.

Chong, Jean-Leon; Wenzel, Pamela L; Sáenz-Robles, M Teresa; Nair, Vivek; Ferrey, Antoney; Hagan, John P; Gomez, Yorman M; Sharma, Nidhi; Chen, Hui-Zi; Ouseph, Madhu; Wang, Shu-Huei; Trikha, Prashant; Culp, Brian; Mezache, Louise; Winton, Douglas J; Sansom, Owen J; Chen, Danian; Bremner, Rod; Cantalupo, Paul G; Robinson, Michael L; Pipas, James M; Leone, Gustavo.

Nature ; 462(7275): 930-4, 2009 Dec 17.

Artigo em Inglês | MEDLINE | ID: mdl-20016602

17.

Induction of the ganglion cell differentiation program in human retinal progenitors before cell cycle exit.

Pacal, Marek; Bremner, Rod.

Dev Dyn ; 243(5): 712-29, 2014 May.

Artigo em Inglês | MEDLINE | ID: mdl-24339342

18.

The search for the retinoblastoma cell of origin.

Dyer, Michael A; Bremner, Rod.

Nat Rev Cancer ; 5(2): 91-101, 2005 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-15685194

19.

The double-stranded RNA-binding protein Staufen 2 regulates eye size.

Cockburn, Diane M; Charish, Jason; Tassew, Nardos G; Eubanks, James; Bremner, Rod; Macchi, Paolo; Monnier, Philippe P.

Mol Cell Neurosci ; 51(3-4): 101-11, 2012 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-22940085

20.

Mapping differentiation kinetics in the mouse retina reveals an extensive period of cell cycle protein expression in post-mitotic newborn neurons.