Detalhe da pesquisa
1.
Phase 1 clinical trial of losmapimod in facioscapulohumeral dystrophy: Safety, tolerability, pharmacokinetics, and target engagement.
Br J Clin Pharmacol
; 87(12): 4658-4669, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33931884
2.
Driving Performance after Bedtime Administration of Daridorexant, Assessed in a Sensitive Simulator.
Clin Pharmacol Ther
; 111(6): 1334-1342, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35426136
3.
Pharmacological Interactions between the Dual Orexin Receptor Antagonist Daridorexant and Ethanol in a Double-Blind, Randomized, Placebo-Controlled, Double-Dummy, Four-Way Crossover Phase I Study in Healthy Subjects.
CNS Drugs
; 34(12): 1253-1266, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33205362
4.
Clinical pharmacology of the dual orexin receptor antagonist ACT-541468 in elderly subjects: Exploration of pharmacokinetics, pharmacodynamics and tolerability following single-dose morning and repeated-dose evening administration.
J Psychopharmacol
; 34(3): 326-335, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31642731
5.
Translational evaluation of novel selective orexin-1 receptor antagonist JNJ-61393215 in an experimental model for panic in rodents and humans.
Transl Psychiatry
; 10(1): 308, 2020 09 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32895369
6.
Multiple-dose clinical pharmacology of ACT-541468, a novel dual orexin receptor antagonist, following repeated-dose morning and evening administration.
Eur Neuropsychopharmacol
; 29(7): 847-857, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31221502
7.
The selective orexin-2 receptor antagonist seltorexant improves sleep: An exploratory double-blind, placebo controlled, crossover study in antidepressant-treated major depressive disorder patients with persistent insomnia.
J Psychopharmacol
; 33(2): 202-209, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30644312
8.
Light Fractionation Significantly Increases the Efficacy of Photodynamic Therapy Using BF-200 ALA in Normal Mouse Skin.
PLoS One
; 11(2): e0148850, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26872051
9.
Sources of variability in the quantification of tissue optical properties by multidiameter single-fiber reflectance and fluorescence spectroscopy.
J Biomed Opt
; 20(5): 57002, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25938208