Detalhe da pesquisa
1.
Filling the gaps on stroke research: Focus on inflammation and immunity.
Brain Behav Immun
; 91: 649-667, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33017613
2.
Melatonin-sulforaphane hybrid ITH12674 attenuates glial response in vivo by blocking LPS binding to MD2 and receptor oligomerization.
Pharmacol Res
; 152: 104597, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31838078
3.
NOX4-dependent neuronal autotoxicity and BBB breakdown explain the superior sensitivity of the brain to ischemic damage.
Proc Natl Acad Sci U S A
; 114(46): 12315-12320, 2017 11 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-29087944
4.
Pharmacological doses of melatonin impede cognitive decline in tau-related Alzheimer models, once tauopathy is initiated, by restoring the autophagic flux.
J Pineal Res
; 67(1): e12578, 2019 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-30943316
5.
The APPswe/PS1A246E mutations in an astrocytic cell line leads to increased vulnerability to oxygen and glucose deprivation, Ca2+ dysregulation, and mitochondrial abnormalities.
J Neurochem
; 145(2): 170-182, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29315575
6.
Neuroprotective effect of melatonin against ischemia is partially mediated by alpha-7 nicotinic receptor modulation and HO-1 overexpression.
J Pineal Res
; 56(2): 204-12, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24350834
7.
Neddylation orchestrates the complex transcriptional and posttranscriptional program that drives Schwann cell myelination.
Sci Adv
; 10(15): eadm7600, 2024 Apr 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38608019
8.
Thrombolysis by PLAT/tPA increases serum free IGF1 leading to a decrease of deleterious autophagy following brain ischemia.
Autophagy
; 18(6): 1297-1317, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34520334
9.
Factor XII protects neurons from apoptosis by epidermal and hepatocyte growth factor receptor-dependent mechanisms.
J Thromb Haemost
; 19(9): 2235-2247, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34060720
10.
Immune Responses and Anti-inflammatory Strategies in a Clinically Relevant Model of Thromboembolic Ischemic Stroke with Reperfusion.
Transl Stroke Res
; 11(3): 481-495, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31522409
11.
Antioxidant, Anti-inflammatory and Neuroprotective Profiles of Novel 1,4-Dihydropyridine Derivatives for the Treatment of Alzheimer's Disease.
Antioxidants (Basel)
; 9(8)2020 Jul 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-32708053
12.
Deficiency in the transcription factor NRF2 worsens inflammatory parameters in a mouse model with combined tauopathy and amyloidopathy.
Redox Biol
; 18: 173-180, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30029164
13.
Apoε4 disrupts neurovascular regulation and undermines white matter integrity and cognitive function.
Nat Commun
; 9(1): 3816, 2018 09 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30232327
14.
Dietary salt promotes neurovascular and cognitive dysfunction through a gut-initiated TH17 response.
Nat Neurosci
; 21(2): 240-249, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29335605
15.
Novel Multitarget Hybrid Compounds for the Treatment of Alzheimer's Disease.
Curr Top Med Chem
; 17(9): 1027-1043, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-27697052
16.
Inclusion complex of ITH12674 with 2-hydroxypropyl-ß-cyclodextrin: Preparation, physical characterization and pharmacological effect.
Carbohydr Polym
; 157: 94-104, 2017 Feb 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27988012
17.
ITH14001, a CGP37157-Nimodipine Hybrid Designed to Regulate Calcium Homeostasis and Oxidative Stress, Exerts Neuroprotection in Cerebral Ischemia.
ACS Chem Neurosci
; 8(1): 67-81, 2017 01 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-27731633
18.
Heme-Oxygenase I and PCG-1α Regulate Mitochondrial Biogenesis via Microglial Activation of Alpha7 Nicotinic Acetylcholine Receptors Using PNU282987.
Antioxid Redox Signal
; 27(2): 93-105, 2017 07 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27554853
19.
Mitochondrial complex I deactivation is related to superoxide production in acute hypoxia.
Redox Biol
; 12: 1040-1051, 2017 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28511347
20.
Novel sulfoglycolipid IG20 causes neuroprotection by activating the phase II antioxidant response in rat hippocampal slices.
Neuropharmacology
; 116: 110-121, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28007500