Detalhe da pesquisa
1.
KRAS Allelic Imbalance Enhances Fitness and Modulates MAP Kinase Dependence in Cancer.
Cell
; 168(5): 817-829.e15, 2017 02 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-28215705
2.
Phase 1 study of anti-CD47 monoclonal antibody CC-90002 in patients with relapsed/refractory acute myeloid leukemia and high-risk myelodysplastic syndromes.
Ann Hematol
; 101(3): 557-569, 2022 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-34981142
3.
Gene dosage effect of CUX1 in a murine model disrupts HSC homeostasis and controls the severity and mortality of MDS.
Blood
; 131(24): 2682-2697, 2018 06 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-29592892
4.
MAGI-2 scaffold protein is critical for kidney barrier function.
Proc Natl Acad Sci U S A
; 111(41): 14876-81, 2014 Oct 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-25271328
5.
Preclinical efficacy of MEK inhibition in Nras-mutant AML.
Blood
; 124(26): 3947-55, 2014 Dec 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-25361812
6.
The creatine kinase pathway is a metabolic vulnerability in EVI1-positive acute myeloid leukemia.
Nat Med
; 23(3): 301-313, 2017 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-28191887
7.
Treating imatinib-resistant leukemia: the next generation targeted therapies.
ScientificWorldJournal
; 6: 918-30, 2006 Aug 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-16906325
8.
Functional evidence implicating chromosome 7q22 haploinsufficiency in myelodysplastic syndrome pathogenesis.
Elife
; 42015 Jul 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-26193121
9.
PLC-γ and PI3K link cytokines to ERK activation in hematopoietic cells with normal and oncogenic Kras.
Sci Signal
; 6(304): ra105, 2013 Dec 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-24300897
10.
Phosphorylation of the ATP-binding loop directs oncogenicity of drug-resistant BCR-ABL mutants.
Proc Natl Acad Sci U S A
; 103(51): 19466-71, 2006 Dec 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-17164333
11.
Comparative analysis of two clinically active BCR-ABL kinase inhibitors reveals the role of conformation-specific binding in resistance.
Proc Natl Acad Sci U S A
; 102(9): 3395-400, 2005 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15705718