Detalhe da pesquisa
1.
Unlocking adult T-cell leukemia/lymphoma's epigenetic secrets: delving into the mechanism and impact of EZH1/2 inhibition.
Immunol Cell Biol
; 102(5): 298-301, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38606590
2.
Jak2V617F and Dnmt3a loss cooperate to induce myelofibrosis through activated enhancer-driven inflammation.
Blood
; 132(26): 2707-2721, 2018 12 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-30366920
3.
Ubiquitous expression of the Pik3caH1047R mutation promotes hypoglycemia, hypoinsulinemia, and organomegaly.
FASEB J
; 29(4): 1426-34, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25550458
4.
Targeting cell cycle and apoptosis to overcome chemotherapy resistance in acute myeloid leukemia.
Leukemia
; 37(1): 143-153, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36400926
5.
Cre recombinase expression cooperates with homozygous FLT3 internal tandem duplication knockin mouse model to induce acute myeloid leukemia.
Leukemia
; 37(4): 741-750, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36739348
6.
Oncogenic drivers dictate immune control of acute myeloid leukemia.
Nat Commun
; 14(1): 2155, 2023 04 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37059710
7.
HRas and Myc synergistically induce cell cycle progression and apoptosis of murine cardiomyocytes.
Front Cardiovasc Med
; 9: 948281, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36337898
8.
A knockout combination for MPN stem cells.
J Exp Med
; 218(2)2021 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33185683
9.
MPN: The Molecular Drivers of Disease Initiation, Progression and Transformation and their Effect on Treatment.
Cells
; 9(8)2020 08 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32823933
10.
Reactivation of Myc transcription in the mouse heart unlocks its proliferative capacity.
Nat Commun
; 11(1): 1827, 2020 04 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32286286
11.
Hematopoietic stem and progenitor cell-restricted Cdx2 expression induces transformation to myelodysplasia and acute leukemia.
Nat Commun
; 11(1): 3021, 2020 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32541670
12.
Distinct effects of ruxolitinib and interferon-alpha on murine JAK2V617F myeloproliferative neoplasm hematopoietic stem cell populations.
Leukemia
; 34(4): 1075-1089, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31732720
13.
Changes in long-range rDNA-genomic interactions associate with altered RNA polymerase II gene programs during malignant transformation.
Commun Biol
; 2: 39, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30701204
14.
Paving the way to improve therapy for Myeloproliferative Neoplasms.
Nat Commun
; 13(1): 5025, 2022 08 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-36028499
15.
Determination of the physiological and pathological roles of E2F3 in adult tissues.
Sci Rep
; 7(1): 9932, 2017 08 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-28855541
16.
Genomic characterisation of Eµ-Myc mouse lymphomas identifies Bcor as a Myc co-operative tumour-suppressor gene.
Nat Commun
; 8: 14581, 2017 03 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28262675
17.
Combination Therapy Targeting Ribosome Biogenesis and mRNA Translation Synergistically Extends Survival in MYC-Driven Lymphoma.
Cancer Discov
; 6(1): 59-70, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26490423
18.
Dysregulation of the basal RNA polymerase transcription apparatus in cancer.
Nat Rev Cancer
; 13(5): 299-314, 2013 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-23612459
19.
AKT signalling is required for ribosomal RNA synthesis and progression of Eµ-Myc B-cell lymphoma in vivo.
FEBS J
; 280(21): 5307-16, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-23331925
20.
The mTORC1 inhibitor everolimus prevents and treats Eµ-Myc lymphoma by restoring oncogene-induced senescence.
Cancer Discov
; 3(1): 82-95, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23242809