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1.
Technol Soc ; 71: 102080, 2022 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-35991080

RESUMO

Personal computers, tablets, and smartphones may support older adults' engagement when people are required to stay home and opportunities to engage in meaningful activities are reduced during the COVID-19 period. This study aims to screen older adults' technology-use characteristics across social, leisure, and education domains during the COVID-19 pandemic from a crosscultural viewpoint. The sample included 576 participants aged 60 and older from France (n = 62), Spain (n = 110), and Israel (n = 404). Participants completed the technology-use survey, which consists of questions about their facilities, technology usability, need for adaptations to support technology use, and changes in technology use since COVID-19. Significant differences were found between countries in facilities, χ2 (2) = 25.16, p < .001, and usability, χ2 (2) = 64.14, p < .001, across the three domains. Furthermore, 34% of technological usability was predicted by country and facilities, F (4, 568) = 72.39, p < .001. Participants noted a willingness to use technology if it was adapted for social (61%-73%), leisure (51%-71%), or educational (67%-76%) activities and that they devoted substantially more time to technology across domains (>58%) due to COVID-19. These findings highlight culture and facilities as factors that play an imperative role in supporting and enhancing the usability of technology among older adults.

2.
J Cell Biochem ; 92(1): 42-52, 2004 May 01.
Artigo em Inglês | MEDLINE | ID: mdl-15095402

RESUMO

Eurythermal fish have evolved compensatory responses to the cyclical seasonal changes of the environment. The complex adaptive mechanisms include the transduction of the physical parameters variations into molecular signals. Studies in carp have indicated that prolactin and growth hormone expression is associated with acclimatization, suggesting that the pituitary gland is a relevant physiological node in the generation of the homeostatic rearrangement that occurs in this adaptive process. Here, we report the cloning and characterization of a full-length carp prolactin receptor cDNA, which codes for the long form of the protein resembling that found in mammalian prolactin receptors. We identified up to three receptor transcript isoforms in different tissues of the teleost and assessed cell- and temporal-specific transcription and protein expression in carp undergoing seasonal acclimatization. The distinctive pattern of expression that carp prolactin receptor (cPRLr) depicts upon seasonal acclimatization supports the hypothesis that prolactin and its receptor are clearly involved in the new homeostatic stage that the eurythermal fish needs to survive during the cyclical changes of its habitat.


Assuntos
Aclimatação/genética , Carpas/genética , Regulação da Expressão Gênica , Receptores da Prolactina/genética , Sequência de Aminoácidos , Animais , Sequência de Bases , Encéfalo/metabolismo , Carpas/metabolismo , Clonagem Molecular , Brânquias/metabolismo , Mucosa Intestinal/metabolismo , Rim/citologia , Rim/metabolismo , Fígado/metabolismo , Masculino , Dados de Sequência Molecular , Hipófise/citologia , Hipófise/metabolismo , RNA Mensageiro/análise , Receptores da Prolactina/biossíntese , Estações do Ano
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