Detalhe da pesquisa
1.
Astrocytic Insulin Signaling Couples Brain Glucose Uptake with Nutrient Availability.
Cell
; 166(4): 867-880, 2016 Aug 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27518562
2.
Regulation of UCP1 and Mitochondrial Metabolism in Brown Adipose Tissue by Reversible Succinylation.
Mol Cell
; 74(4): 844-857.e7, 2019 05 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-31000437
3.
Loss of insulin signaling in astrocytes exacerbates Alzheimer-like phenotypes in a 5xFAD mouse model.
Proc Natl Acad Sci U S A
; 120(21): e2220684120, 2023 05 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-37186836
4.
Knockout of the intellectual disability-linked gene Hs6st2 in mice decreases heparan sulfate 6-O-sulfation, impairs dendritic spines of hippocampal neurons, and affects memory.
Glycobiology
; 34(2)2024 Mar 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38015989
5.
Transcriptome and secretome profiling of sensory neurons reveals sex differences in pathways relevant to insulin sensing and insulin secretion.
FASEB J
; 37(10): e23185, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37695721
6.
Distinct signaling by insulin and IGF-1 receptors and their extra- and intracellular domains.
Proc Natl Acad Sci U S A
; 118(17)2021 04 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-33879610
7.
Arrestin domain-containing 3 (Arrdc3) modulates insulin action and glucose metabolism in liver.
Proc Natl Acad Sci U S A
; 117(12): 6733-6740, 2020 03 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-32156724
8.
Obesity-related vascular dysfunction persists after weight loss and is associated with decreased vascular glucagon-like peptide receptor in female rats.
Am J Physiol Heart Circ Physiol
; 323(2): H301-H311, 2022 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35749717
9.
Insulin signaling in the hippocampus and amygdala regulates metabolism and neurobehavior.
Proc Natl Acad Sci U S A
; 116(13): 6379-6384, 2019 03 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-30765523
10.
Viral insulin-like peptides activate human insulin and IGF-1 receptor signaling: A paradigm shift for host-microbe interactions.
Proc Natl Acad Sci U S A
; 115(10): 2461-2466, 2018 03 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29467286
11.
Resveratrol Promotes Angiogenesis in a FoxO1-Dependent Manner in Hind Limb Ischemia in Mice.
Molecules
; 26(24)2021 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34946610
12.
Endothelial insulin receptors differentially control insulin signaling kinetics in peripheral tissues and brain of mice.
Proc Natl Acad Sci U S A
; 114(40): E8478-E8487, 2017 10 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28923931
13.
RIT1 GTPase Regulates Sox2 Transcriptional Activity and Hippocampal Neurogenesis.
J Biol Chem
; 292(6): 2054-2064, 2017 02 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28007959
14.
Insulin resistance in brain alters dopamine turnover and causes behavioral disorders.
Proc Natl Acad Sci U S A
; 112(11): 3463-8, 2015 Mar 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-25733901
15.
Construction of a Robust Radiative Cooling Emitter for Efficient Food Storage and Transportation.
ACS Appl Mater Interfaces
; 2024 Apr 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38684025
16.
Rit GTPase signaling promotes immature hippocampal neuronal survival.
J Neurosci
; 32(29): 9887-97, 2012 Jul 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-22815504
17.
Rit-mediated stress resistance involves a p38-mitogen- and stress-activated protein kinase 1 (MSK1)-dependent cAMP response element-binding protein (CREB) activation cascade.
J Biol Chem
; 287(47): 39859-68, 2012 Nov 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-23038261
18.
Unique ligand and kinase-independent roles of the insulin receptor in regulation of cell cycle, senescence and apoptosis.
Nat Commun
; 14(1): 57, 2023 01 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36599833
19.
Leucine-973 is a crucial residue differentiating insulin and IGF-1 receptor signaling.
J Clin Invest
; 133(4)2023 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36548088
20.
RIT1 regulation of CNS lipids RIT1 deficiency Alters cerebral lipid metabolism and reduces white matter tract oligodendrocytes and conduction velocities.
Heliyon
; 9(10): e20384, 2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-37780758