Detalhe da pesquisa
1.
Chemical disarming of isoniazid resistance in Mycobacterium tuberculosis.
Proc Natl Acad Sci U S A
; 116(21): 10510-10517, 2019 05 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31061116
2.
Viral mimetic priming enhances α-synuclein-induced degeneration: Implications for Parkinson's disease.
Brain Behav Immun
; 80: 525-535, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31029796
3.
Pyridine-Fused 2-Pyridones via Povarov and A3 Reactions: Rapid Generation of Highly Functionalized Tricyclic Heterocycles Capable of Amyloid Fibril Binding.
J Org Chem
; 84(7): 3887-3903, 2019 04 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30862161
4.
Individuals with higher metabolic rates have lower levels of reactive oxygen species in vivo.
Biol Lett
; 11(9): 20150538, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26382073
5.
Synthesis of an azido-tagged low affinity ratiometric calcium sensor.
Tetrahedron
; 71(51): 9571-9578, 2015 Dec 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-26709317
6.
Expanding the palette of phenanthridinium cations.
Chemistry
; 20(13): 3742-51, 2014 Mar 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-24677631
7.
Targeted protein degradation in CNS disorders: a promising route to novel therapeutics?
Front Mol Neurosci
; 17: 1370509, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38685916
8.
Selective uncoupling of individual mitochondria within a cell using a mitochondria-targeted photoactivated protonophore.
J Am Chem Soc
; 134(2): 758-61, 2012 Jan 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-22239373
9.
Insights on Targeting Small Molecules to the Mitochondrial Matrix and the Preparation of MitoB and MitoP as Exomarkers of Mitochondrial Hydrogen Peroxide.
Methods Mol Biol
; 2275: 87-117, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34118033
10.
The Small Molecule Alpha-Synuclein Aggregator, FN075, Enhances Alpha-Synuclein Pathology in Subclinical AAV Rat Models.
Biomolecules
; 11(11)2021 11 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34827685
11.
Translation of Diverse Aramid- and 1,3-Dicarbonyl-peptides by Wild Type Ribosomes in Vitro.
ACS Cent Sci
; 5(7): 1289-1294, 2019 Jul 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-31403077
12.
Synthesis of Densely Functionalized N-Alkenyl 2-Pyridones via Benzyne-Induced Ring Opening of Thiazolino-Fused 2-Pyridones.
Org Lett
; 21(17): 6946-6950, 2019 09 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31419146
13.
Methyl sulfonamide substituents improve the pharmacokinetic properties of bicyclic 2-pyridone based Chlamydia trachomatis inhibitors.
Medchemcomm
; 10(11): 1966-1987, 2019 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32206238
14.
Increased Brain Exposure of an Alpha-Synuclein Fibrillization Modulator by Utilization of an Activated Ester Prodrug Strategy.
ACS Chem Neurosci
; 9(11): 2542-2547, 2018 11 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-29901990
15.
Structure-Based Design of Inhibitors Targeting PrfA, the Master Virulence Regulator of Listeria monocytogenes.
J Med Chem
; 61(9): 4165-4175, 2018 05 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29667825
16.
Using the MitoB method to assess levels of reactive oxygen species in ecological studies of oxidative stress.
Sci Rep
; 7: 41228, 2017 01 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-28117373
17.
MitoNeoD: A Mitochondria-Targeted Superoxide Probe.
Cell Chem Biol
; 24(10): 1285-1298.e12, 2017 Oct 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-28890317
18.
Regio- and Stereoselective Alkylation of Pyridine-N-oxides: Synthesis of Substituted Piperidines and Pyridines.
Org Lett
; 18(24): 6228-6231, 2016 12 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-27978656
19.
Targeting mitochondria with small molecules: the preparation of MitoB and MitoP as exomarkers of mitochondrial hydrogen peroxide.
Methods Mol Biol
; 1265: 25-50, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25634265