1.
Bioorg Med Chem
; 11(16): 3413-21, 2003 Aug 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-12878136
RESUMO
An array of 4-(aryl or indolyl)pyrrolo[3,4-c]carbazole-1,3-diones (open analogues of indolocarbazole alkaloids), 10-(aryl or indolyl)pyrrolo[3,4-b]carbazole-1,3-diones, and different derivatives have been prepared using a Diels-Alder plus Fischer indolization approach and tested as cytotoxic agents. Some representative compounds display interesting cytotoxic profiles.