Detalhe da pesquisa
1.
Correction of amyotrophic lateral sclerosis related phenotypes in induced pluripotent stem cell-derived motor neurons carrying a hexanucleotide expansion mutation in C9orf72 by CRISPR/Cas9 genome editing using homology-directed repair.
Hum Mol Genet
; 29(13): 2200-2217, 2020 08 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32504093
2.
Interaction between a Novel Oligopeptide Fragment of the Human Neurotrophin Receptor TrkB Ectodomain D5 and the C-Terminal Fragment of Tetanus Neurotoxin.
Molecules
; 26(13)2021 Jun 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-34208805
3.
An ALS-linked mutation in TDP-43 disrupts normal protein interactions in the motor neuron response to oxidative stress.
Neurobiol Dis
; 144: 105050, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32800996
4.
The State of the Art and Challenges of In Vitro Methods for Human Hazard Assessment of Nanomaterials in the Context of Safe-by-Design.
Nanomaterials (Basel)
; 13(3)2023 Jan 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-36770432
5.
C9orf72-ALS human iPSC microglia are pro-inflammatory and toxic to co-cultured motor neurons via MMP9.
Nat Commun
; 14(1): 5898, 2023 09 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-37736756
6.
Human iPSC co-culture model to investigate the interaction between microglia and motor neurons.
Sci Rep
; 12(1): 12606, 2022 07 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35871163
7.
Impairment of Mitochondrial Calcium Buffering Links Mutations in C9ORF72 and TARDBP in iPS-Derived Motor Neurons from Patients with ALS/FTD.
Stem Cell Reports
; 14(5): 892-908, 2020 05 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32330447
8.
Truncated stathmin-2 is a marker of TDP-43 pathology in frontotemporal dementia.
J Clin Invest
; 130(11): 6080-6092, 2020 11 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32790644
9.
Intra-hippocampal D-cycloserine rescues decreased social memory, spatial learning reversal, and synaptophysin levels in aged rats.
Psychopharmacology (Berl)
; 235(5): 1463-1477, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29492616
10.
Trk receptors need neutral sphingomyelinase activity to promote cell viability.
FEBS Lett
; 588(1): 167-74, 2014 Jan 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-24316227
11.
Tetanus Toxin Hc Fragment Induces the Formation of Ceramide Platforms and Protects Neuronal Cells against Oxidative Stress.
PLoS One
; 8(6): e68055, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23826362
12.
Effect of the C-terminal domain of the heavy chain of tetanus toxin on dyskinesia caused by levodopa in 6-hydroxydopamine-lesioned rats.
Pharmacol Biochem Behav
; 145: 33-44, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27090294