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1.
Medicine (Baltimore) ; 98(20): e15687, 2019 May.
Artigo em Inglês | MEDLINE | ID: mdl-31096507

RESUMO

RATIONALE: Acupuncture is a significant feature of traditional Chinese medicine, which can dredge the channels, harmonize qi and blood, replenish deficiency and relieve excess, strengthen the body and remove pathogens to treat urinary incontinence after hysterectomy, and improve the quality of life, which is simple, convenient, inexpensive, and practical. PATIENT CONCERNS: After a total hysterectomy, the catheter was retained every day, causing urinary incontinence and elderly urine wetness for 30 days. DIAGNOSES: Postoperative urinary incontinence for 1 month; type 2 diabetes for 4 years. Hypertension for 2 years. INTERVENTIONS: From the first month after operation, acupuncture on bilateral, Ciliao (BL32), Zhongliao (BL33), and Xialiao (BL34). OUTCOMES: The patient experienced bladder fullness on the 2nd day. On the 3rd day, the patient could arose from bed and urinated on her own. On the 4th day, she could urinate freely. The time and frequency of urination were normal. LESSONS: acupuncture is safe and effective mode for the treatment of urinary incontinence issues after total hysterectomy. It greatly improves the quality of life and daily wellbeing.


Assuntos
Terapia por Acupuntura/métodos , Histerectomia/efeitos adversos , Incontinência Urinária/etiologia , Incontinência Urinária/terapia , Idoso , Diabetes Mellitus Tipo 2/complicações , Feminino , Humanos , Hipertensão/complicações , Qualidade de Vida
2.
Artigo em Inglês | MEDLINE | ID: mdl-31534466

RESUMO

Moxibustion has been widely accepted as an alternative therapy for major depressive disease (MDD). However, the efficacy of moxibustion treatment on MDD is highly variable because of its irregular operation. This study was designed to investigate how therapeutic duration and extent influence the anti-depression effect of moxibustion and the underlying mechanism involved. Rats with lipopolysaccharide-induced depression-like behavior were treated by moxibustion treatment. The anti-depression effect was determined by forced swimming test and open field test. Tryptophan (Trp) transport and its metabolism to serotonin (5-HT) and kynurenine (Kyn) were evaluated to explore the anti-depression mechanism. The results showed that moxibustion treatment could alleviate the depression-like behavior in rats. Trp transport and 5-HT generation were significantly increased, and the Trp-Kyn pathway was moderately inhibited by moxibustion. Prolonged therapy could be beneficial to the anti-depression effect by promoting the brain uptake of Trp and shifting the Trp metabolism to 5-HT. An enhanced therapeutic extent could increase 5-HT generation. In conclusion, this study determined that the anti-depression effect of moxibustion involves improved Trp transport and metabolism. The therapeutic duration benefits antidepressant effects, but the complex influence of the therapeutic extent on moxibustion efficacy requires further studies.

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