Development of global soil erosion research at the watershed scale: a bibliometric analysis of the past decade.

At the watershed scale, soil erosion is a cascading system that includes detachment-transport-deposition processes while sediment yield is the net balance of detachment and deposition at the watershed outlet. Due to the temporal-spatial variations of rainfall and landscapes, the relationships between soil erosion and sediment yield are complex and non-linear. Soil erosion processes and sediment yield at the watershed scale have attracted widespread attention; however, few systematic studies have been performed. In this study, a bibliometric analysis and visualization are used to understand the global research status of soil erosion and sediment yield at the watershed scale and provide a reference for researchers to establish future research directions. The USA and China were the most active contributors and had the most publications and active institutions, while Jean Poesen, D.E. Walling, and Xingmin Mu were the top three lead authors in this field. A keyword evolution analysis showed that determining the relationship between soil erosion and the watershed landscape and identifying the sediment source and off-site environmental and ecological effects caused by soil erosion have attracted considerable research attention. Additionally, significant progress has been made in the study of "connectivity," and future research should integrate connectivity and soil erosion models to explain the soil erosion, sediment transport, and deposition processes at the watershed scale.

Feasibility study of a human papillomavirus E6 and E7 oncoprotein test for the diagnosis of cervical precancer and cancer.

Objective To evaluate the clinical value of human papillomavirus (HPV) E6 and E7 oncoprotein (HPV E6/E7) detection in the early screening of cervical cancer. Methods This prospective study evaluated all patients with suspected cervical intraepithelial neoplasia (CIN) as identified by the presence of at least one positive indicator from a ThinPrep cytologic test (TCT) and/or a Hybrid Capture 2 (HC2) HPV DNA test. The levels of E6/E7 oncoproteins were determined using Western blot analysis. The diagnostic value of the HPV E6/E7 protein assay was compared with the clinical diagnosis from TCT, HC2 and the gold standard of cervical biopsy histology. Results A total of 450 patients were enrolled in the study and based on histological findings, 102 patients were diagnosed with CIN1 (22.7%), 241 with CIN2 (53.6%), 96 with CIN3 (21.3%) and 11 with squamous cell carcinoma (2.4%). For a diagnosis of CIN2+, although the sensitivity of the HPV E6/E7 assay was lower than HC2 (65.5% versus 96.6%, respectively), the specificity was higher (38.2% versus 5.9%, respectively). The sensitivity of the HPV E6/E7 assay was higher than TCT (65.5% versus 36.2%, respectively). Conclusion Measuring HPV E6/E7 oncoprotein levels is a potential new biomarker for HPV type 16.

[Investigation on the impact of imported cases on filariasis elimination program in Shandong Province].

OBJECTIVE: To study the impact of imported filariasis cases on the elimination program in different areas of Shandong Province. METHODS: Dezhou was selected as former low endemic area and Yicheng as former high endemic area. Blood examination was carried out for both mobile population and local people for microfilariae(Mf). Mosquitoes were caught in field and dissected to count the ratio of those having laid eggs and the natural filarial infection rate. Mosquitoes reared at different temperatures were fed with Mf-positive blood and dissected after certain time period to observe the development of the larvae. The vectorial capacity and case transmission quantity were calculated and compared with those from different areas. RESULTS: The Mf positive rate of inflow population was 3.18% in average. No case was detected from 9,411 local residents after blood exam in Dezhou while 2 out of 692 local residents were found Mf positive in Yicheng. Mosquitoes natural infection rate was 3.81% but no third stage larva was found. The shortest time period needed for the larva to develop into an infective stage was 16 days in Dezhou and 11 days in Yicheng. The time period from blood meal to egg-laying on average was 4.95 days in Dezhou and 4.33 days in Yicheng. The ratio of vectorial capacity and case transmission quantity was 1:4.41 and 1:5.82 respectively in Dezhou and Yicheng. CONCLUSION: Filarial transmission seems unlikely in Dezhou for its low vectorial capacity and low transmission quantity resulted from low and evidently fluctuating temperature in the north. A low level filarial transmission may be possible in former high-endemic area such as Yicheng if there are as many imported cases as in Dezhou.