Detalhe da pesquisa
1.
Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.
J Biol Chem
; 299(3): 102888, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36634849
2.
Therapeutic Trial of anle138b in Mouse Models of Genetic Prion Disease.
J Virol
; 97(2): e0167222, 2023 02 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-36651748
3.
Prion protein lowering is a disease-modifying therapy across prion disease stages, strains and endpoints.
Nucleic Acids Res
; 48(19): 10615-10631, 2020 11 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32776089
4.
Disruption of Fnip1 reveals a metabolic checkpoint controlling B lymphocyte development.
Immunity
; 36(5): 769-81, 2012 May 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-22608497
5.
How an Infection of Sheep Revealed Prion Mechanisms in Alzheimer's Disease and Other Neurodegenerative Disorders.
Int J Mol Sci
; 22(9)2021 May 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34064393
6.
Evidence for sortilin modulating regional accumulation of human tau prions in transgenic mice.
Proc Natl Acad Sci U S A
; 114(51): E11029-E11036, 2017 12 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-29203673
7.
High resolution time-course mapping of early transcriptomic, molecular and cellular phenotypes in Huntington's disease CAG knock-in mice across multiple genetic backgrounds.
Hum Mol Genet
; 26(5): 913-922, 2017 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28334820
8.
Removing endogenous tau does not prevent tau propagation yet reduces its neurotoxicity.
EMBO J
; 34(24): 3028-41, 2015 Dec 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-26538322
9.
Brain Perivascular Macrophages Initiate the Neurovascular Dysfunction of Alzheimer Aß Peptides.
Circ Res
; 121(3): 258-269, 2017 Jul 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-28515043
10.
Tau reduction in the presence of amyloid-ß prevents tau pathology and neuronal death in vivo.
Brain
; 141(7): 2194-2212, 2018 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29733334
11.
Reduction of ciliary length through pharmacologic or genetic inhibition of CDK5 attenuates polycystic kidney disease in a model of nephronophthisis.
Hum Mol Genet
; 25(11): 2245-2255, 2016 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27053712
12.
Enhanced Tau Aggregation in the Presence of Amyloid ß.
Am J Pathol
; 187(7): 1601-1612, 2017 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-28500862
13.
Tau Antibody Targeting Pathological Species Blocks Neuronal Uptake and Interneuron Propagation of Tau in Vitro.
Am J Pathol
; 187(6): 1399-1412, 2017 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-28408124
14.
Seed-competent high-molecular-weight tau species accumulates in the cerebrospinal fluid of Alzheimer's disease mouse model and human patients.
Ann Neurol
; 80(3): 355-67, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27351289
15.
Spread of tau down neural circuits precedes synapse and neuronal loss in the rTgTauEC mouse model of early Alzheimer's disease.
Synapse
; 71(6)2017 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28196395
16.
Human tau increases amyloid ß plaque size but not amyloid ß-mediated synapse loss in a novel mouse model of Alzheimer's disease.
Eur J Neurosci
; 44(12): 3056-3066, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27748574
17.
Caspase activation precedes and leads to tangles.
Nature
; 464(7292): 1201-4, 2010 Apr 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-20357768
18.
Familial dysautonomia model reveals Ikbkap deletion causes apoptosis of Pax3+ progenitors and peripheral neurons.
Proc Natl Acad Sci U S A
; 110(46): 18698-703, 2013 Nov 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-24173031
19.
Innate immunity receptor CD36 promotes cerebral amyloid angiopathy.
Proc Natl Acad Sci U S A
; 110(8): 3089-94, 2013 Feb 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-23382216
20.
Disrupted SOX10 function causes spongiform neurodegeneration in gray tremor mice.
Mamm Genome
; 26(1-2): 80-93, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25399070