Detalhe da pesquisa
1.
Lactate supports cell-autonomous ECM production to sustain metastatic behavior in prostate cancer.
EMBO Rep
; 2024 Jun 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38907027
2.
A functional SNP regulates E-cadherin expression by dynamically remodeling the 3D structure of a promoter-associated non-coding RNA transcript.
Nucleic Acids Res
; 50(19): 11331-11343, 2022 10 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-36243981
3.
Deciphering the complexity of human non-coding promoter-proximal transcriptome.
Bioinformatics
; 35(15): 2529-2534, 2019 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30535182
4.
Tumour-infiltrating Gr-1+ myeloid cells antagonize senescence in cancer.
Nature
; 515(7525): 134-7, 2014 Nov 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-25156255
5.
Mitochondrial dysfunction induced by a SH2 domain-targeting STAT3 inhibitor leads to metabolic synthetic lethality in cancer cells.
Proc Natl Acad Sci U S A
; 114(25): E4924-E4933, 2017 06 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-28584133
6.
Structural Biology of STAT3 and Its Implications for Anticancer Therapies Development.
Int J Mol Sci
; 19(6)2018 May 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-29843450
7.
Natural antisense transcripts drive a regulatory cascade controlling c-MYC transcription.
RNA Biol
; 14(12): 1742-1755, 2017 12 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28805496
8.
Short loop-targeting oligoribonucleotides antagonize Lin28 and enable pre-let-7 processing and suppression of cell growth in let-7-deficient cancer cells.
Nucleic Acids Res
; 43(2): e9, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25378324
9.
Aphanin, a triterpenoid from Amoora rohituka inhibits K-Ras mutant activity and STAT3 in pancreatic carcinoma cells.
Tumour Biol
; 37(9): 12455-12464, 2016 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-27333990
10.
Molecular Determinants for Unphosphorylated STAT3 Dimerization Determined by Integrative Modeling.
Biochemistry
; 54(35): 5489-501, 2015 Sep 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-26283080
11.
Promoter-specific transcriptional interference and c-myc gene silencing by siRNAs in human cells.
EMBO J
; 28(12): 1708-19, 2009 Jun 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-19461583
12.
Preclinical Models of Neuroendocrine Prostate Cancer.
Curr Protoc
; 3(5): e742, 2023 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-37166213
13.
Proteomics of immune cells from liver tumors reveals immunotherapy targets.
Cell Genom
; 3(6): 100331, 2023 Jun 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37388918
14.
An open-label phase 2 study of twice-weekly bortezomib and intermittent pegylated liposomal doxorubicin in patients with ovarian cancer failing platinum-containing regimens.
Int J Gynecol Cancer
; 22(5): 792-800, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22635029
15.
Synthesis of Aminoethyl-Substituted Piperidine Derivatives as σ1 Receptor Ligands with Antiproliferative Properties.
ChemMedChem
; 17(7): e202100735, 2022 04 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35077612
16.
Pharmacological inhibition of Lin28 promotes ketogenesis and restores lipid homeostasis in models of non-alcoholic fatty liver disease.
Nat Commun
; 13(1): 7940, 2022 12 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-36572670
17.
Lactate Rewires Lipid Metabolism and Sustains a Metabolic-Epigenetic Axis in Prostate Cancer.
Cancer Res
; 82(7): 1267-1282, 2022 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35135811
18.
Pharmacodynamic and Pharmacokinetic Properties of Full Phosphorothioate Small Interfering RNAs for Gene Silencing In Vivo.
Nucleic Acid Ther
; 31(3): 237-244, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32311310
19.
Efficacy of Novel Bromodomain and Extraterminal Inhibitors in Combination with Chemotherapy for Castration-Resistant Prostate Cancer.
Eur Urol Oncol
; 4(3): 437-446, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31402217
20.
Mitochondrial Plasticity Promotes Resistance to Sorafenib and Vulnerability to STAT3 Inhibition in Human Hepatocellular Carcinoma.
Cancers (Basel)
; 13(23)2021 Nov 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-34885140