Detalhe da pesquisa
1.
CFI-402257, a TTK inhibitor, effectively suppresses hepatocellular carcinoma.
Proc Natl Acad Sci U S A
; 119(32): e2119514119, 2022 08 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35914158
2.
Inhibition of CAF-1 histone chaperone complex triggers cytosolic DNA and dsRNA sensing pathways and induces intrinsic immunity of hepatocellular carcinoma.
Hepatology
; 2023 Dec 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38051950
3.
Polo-like kinase 4 inhibitor CFI-400945 suppresses liver cancer through cell cycle perturbation and eliciting antitumor immunity.
Hepatology
; 77(3): 729-744, 2023 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35302667
4.
Using mouse liver cancer models based on somatic genome editing to predict immune checkpoint inhibitor responses.
J Hepatol
; 78(2): 376-389, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36455783
5.
Adaptive and Constitutive Activations of Malic Enzymes Confer Liver Cancer Multilayered Protection Against Reactive Oxygen Species.
Hepatology
; 74(2): 776-796, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33619771
6.
HELLS Regulates Chromatin Remodeling and Epigenetic Silencing of Multiple Tumor Suppressor Genes in Human Hepatocellular Carcinoma.
Hepatology
; 69(5): 2013-2030, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30516846
7.
Induction of Oxidative Stress Through Inhibition of Thioredoxin Reductase 1 Is an Effective Therapeutic Approach for Hepatocellular Carcinoma.
Hepatology
; 69(4): 1768-1786, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30561826
8.
Hypoxia and the Metastatic Niche.
Adv Exp Med Biol
; 1136: 97-112, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31201719
9.
Ferroptosis Suppressor Protein 1 Inhibition Promotes Tumor Ferroptosis and Anti-tumor Immune Responses in Liver Cancer.
Cell Mol Gastroenterol Hepatol
; 16(1): 133-159, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36893885
10.
Hypoxia-inducible factor orchestrates adenosine metabolism to promote liver cancer development.
Sci Adv
; 9(18): eade5111, 2023 05 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37146141
11.
Genome-Wide CRISPR/Cas9 Library Screening Revealed Dietary Restriction of Glutamine in Combination with Inhibition of Pyruvate Metabolism as Effective Liver Cancer Treatment.
Adv Sci (Weinh)
; 9(34): e2202104, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36310121
12.
Genome-wide CRISPR-Cas9 knockout library screening identified PTPMT1 in cardiolipin synthesis is crucial to survival in hypoxia in liver cancer.
Cell Rep
; 34(4): 108676, 2021 01 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-33503428
13.
Hepatitis transactivator protein X promotes extracellular matrix modification through HIF/LOX pathway in liver cancer.
Oncogenesis
; 7(5): 44, 2018 May 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-29799025
14.
Folate cycle enzyme MTHFD1L confers metabolic advantages in hepatocellular carcinoma.
J Clin Invest
; 127(5): 1856-1872, 2017 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28394261